| 1 | Mon Nov 4 | vs TBD | W91-68 | 1-0 | 1.000 | - | | Swinney Recreation Center · Kansas City, MO |
| 2 | Fri Nov 8 | vsTBD | W124-36 | 2-0 | 1.000 | - | | Swinney Recreation Center · Kansas City, MO |
| 3 | Mon Nov 11 | at #7Iowa State | L56-82 | 2-1 | .667 | - | ESPN+ | James H. Hilton Coliseum · Ames, IA |
| 4 | Sat Nov 16 | at #14Creighton | L56-79 | 2-2 | .500 | - | FS2 | CHI Health Center Omaha · Omaha, NE |
| 5 | Mon Nov 18 | vsTBD | W119-19 | 3-2 | .600 | - | | Swinney Recreation Center · Kansas City, MO |
| 6 | Fri Nov 22 | at American | L60-64 | 3-3 | .500 | - | | Bender Arena · Washington, D.C. |
| 7 | Sat Nov 23 | vs Albany | L65-67 | 3-4 | .429 | - | | Swinney Recreation Center · Kansas City, MO |
| 8 | Sun Nov 24 | atTBD | W88-55 | 4-4 | .500 | - | | Ruben Rodriguez Coliseum |
| 9 | Sat Nov 30 | at SE Missouri St | L59-80 | 4-5 | .444 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 10 | Wed Dec 4 | vs Idaho | L77-82 | 4-6 | .400 | - | | Swinney Recreation Center · Kansas City, MO |
| 11 | Sat Dec 7 | at Montana St | L62-74 | 4-7 | .364 | - | ESPN+ | Worthington Arena · Bozeman, MT |
| 12 | Tue Dec 10 | at Portland | W69-64 | 5-7 | .417 | - | ESPN+ | Chiles Center · Portland, OR |
| 13 | Sat Dec 14 | vs Bowling Green | W85-77 | 6-7 | .462 | - | | Swinney Recreation Center · Kansas City, MO |
| 14 | Tue Dec 17 | at Wichita St | W74-64 | 7-7 | .500 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 15 | Sat Dec 21 | vs ETSU | W73-66 | 8-7 | .533 | - | | Swinney Recreation Center · Kansas City, MO |
| 16 | Thu Jan 2 | vs South Dakota | W68-54 | 9-7 | .563 | - | | Swinney Recreation Center · Kansas City, MO |
| 17 | Sat Jan 4 | vs Oral Roberts | W90-67 | 10-7 | .588 | - | | Swinney Recreation Center · Kansas City, MO |
| 18 | Wed Jan 8 | at Omaha | L58-77 | 10-8 | .556 | - | CBS | Baxter Arena · Omaha, NE |
| 19 | Thu Jan 16 | at N Dakota St | L64-71 | 10-9 | .526 | - | | Scheels Center · Fargo, ND |
| 20 | Sat Jan 18 | at North Dakota | L72-76 | 10-10 | .500 | - | | Betty Engelstad Sioux Center · Grand Forks, ND |
| 21 | Thu Jan 23 | vs S Dakota St | L64-65 | 10-11 | .476 | - | | Swinney Recreation Center · Kansas City, MO |
| 22 | Sat Jan 25 | vs St Thomas (MN) | L65-68 | 10-12 | .455 | - | | Swinney Recreation Center · Kansas City, MO |
| 23 | Thu Jan 30 | at Denver | L68-69 | 10-13 | .435 | - | | Hamilton Gymnasium · Denver, CO |
| 24 | Sat Feb 1 | atOral Roberts | L67-73 | 10-14 | .417 | - | | Mabee Center · Tulsa, OK |
| 25 | Thu Feb 6 | vsN Dakota St | L72-78 | 10-15 | .400 | - | | Swinney Recreation Center · Kansas City, MO |
| 26 | Sat Feb 8 | vsNorth Dakota | W80-69 | 11-15 | .423 | - | | Swinney Recreation Center · Kansas City, MO |
| 27 | Thu Feb 13 | atSouth Dakota | L72-79 | 11-16 | .407 | - | | Sanford Coyote Sports Center · Vermillion, SD |
| 28 | Wed Feb 19 | vsOmaha | L66-78 | 11-17 | .393 | - | | Swinney Recreation Center · Kansas City, MO |
