| 1 | Tue Nov 4 | at 10Texas Tech | L60-98 | 0-1 | .000 | - | ESPN+ | United Supermarkets Arena · Lubbock, TX |
| 2 | Thu Nov 6 | vsTBD | W116-51 | 1-1 | .500 | - | ESPN+ | placeholder · sf, ca |
| 3 | Mon Nov 10 | atSaint Louis | L66-109 | 1-2 | .333 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 4 | Fri Nov 14 | atCharleston So | W83-77 | 2-2 | .500 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 5 | Sun Nov 16 | atAlabama A&M | L65-74 | 2-3 | .400 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 6 | Thu Nov 20 | atIndiana | L53-73 | 2-4 | .333 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 7 | Mon Nov 24 | vsKansas City | W80-67 | 3-4 | .429 | - | ESPN+ | placeholder · sf, ca |
| 8 | Tue Dec 2 | atN Illinois | W99-64 | 4-4 | .500 | - | ESPN+ | NIU Convocation Center · Dekalb, IL |
| 9 | Sat Dec 6 | atE Illinois | W82-74 | 5-4 | .556 | - | ESPN+ | Lantz Arena · Charleston, IL |
| 10 | Tue Dec 9 | vsTBD | W110-44 | 6-4 | .600 | - | ESPN+ | placeholder · sf, ca |
| 11 | Thu Dec 18 | vsW Illinois | W92-76 | 7-4 | .636 | - | ESPN+ | placeholder · sf, ca |
| 12 | Sat Dec 20 | vsTBD | W109-52 | 8-4 | .667 | - | ESPN+ | placeholder · sf, ca |
| 13 | Tue Dec 23 | atMissouri St | L65-70 | 8-5 | .615 | - | ESPN+ | Great Southern Bank Arena · Springfield, MO |
| 14 | Thu Jan 1 | vsMorehead St | W77-64 | 9-5 | .643 | - | ESPN+ | placeholder · sf, ca |
| 15 | Sat Jan 3 | vsSo Indiana | W83-80 | 10-5 | .667 | - | ESPN+ | placeholder · sf, ca |
| 16 | Tue Jan 6 | atSIUE | L62-66 | 10-6 | .625 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 17 | Sat Jan 10 | vsLittle Rock | L74-82 | 10-7 | .588 | - | ESPN+ | placeholder · sf, ca |
| 18 | Thu Jan 15 | atSE Missouri St | W88-76 | 11-7 | .611 | - | ESPNU | Show Me Center · Cape Girardeau, MO |
| 19 | Sat Jan 17 | atUT Martin | L55-69 | 11-8 | .579 | - | ESPN+ | Kathleen and Tom Elam Center · Martin, TN |
| 20 | Thu Jan 22 | vsTennessee Tech | W89-68 | 12-8 | .600 | - | ESPN+ | placeholder · sf, ca |
| 21 | Sat Jan 24 | vsTennessee St | L86-96 | 12-9 | .571 | - | ESPN+ | placeholder · sf, ca |
| 22 | Thu Jan 29 | atSo Indiana | W73-60 | 13-9 | .591 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 23 | Sat Jan 31 | atMorehead St | W79-78 | 14-9 | .609 | - | ESPN+ | Ellis T. Johnson Arena · Morehead, KY |
| 24 | Tue Feb 3 | vsSIUE | L72-78 | 14-10 | .583 | - | ESPN+ | placeholder · sf, ca |
| 25 | Thu Feb 5 | atLittle Rock | W79-74 | 15-10 | .600 | - | ESPN+ | Jack Stephens Center · Little Rock, AR |
| 26 | Thu Feb 12 | vsUT Martin | W75-74 | 16-10 | .615 | - | ESPN+ | placeholder · sf, ca |
| 27 | Sat Feb 14 | vsSE Missouri St | L61-73 | 16-11 | .593 | - | ESPN+ | placeholder · sf, ca |
| 28 | Thu Feb 19 | atTennessee St | L80-89 | 16-12 | .571 | - | ESPN+ | Gentry Center · Nashville, TN |
| 29 | Sat Feb 21 | atTennessee Tech | L57-72 | 16-13 | .552 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 30 | Thu Feb 26 | vsE Illinois | L67-71 | 16-14 | .533 | - | ESPN+ | placeholder · sf, ca |
| 31 | Sat Feb 28 | atW Illinois | W91-69 | 17-14 | .548 | - | ESPN+ | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
