| 1 | Mon Nov 3 | at Duquesne | 7:00 PM | 13-19 | .406 | - | ESPN+ | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 2 | Sat Nov 8 | atBinghamton | 2:00 PM | 15-17 | .469 | - | ESPN+ | Events Center (Binghamton) · Binghamton, NY |
| 3 | Mon Nov 10 | vsDelaware St | TBD | 16-14 | .533 | - | ESPN+ | Gallagher Center · Niagara Falls, NY |
| 4 | Mon Nov 17 | atLe Moyne | 7:00 PM | 9-23 | .281 | - | | Ted Grant Court · Syracuse, NY |
| 5 | Fri Nov 21 | at#6Duke | 7:00 PM | 35-4 | .897 | - | ACC Network | Cameron Indoor Stadium · Durham, NC |
| 6 | Sat Nov 22 | atHoward | TBD | 12-20 | .375 | - | | Burr Gymnasium · Washington, D.C. |
| 7 | Sat Nov 29 | vsDetroit Mercy | 1:00 PM | 8-24 | .250 | - | ESPN+ | Gallagher Center · Niagara Falls, NY |
| 8 | Fri Dec 5 | atSiena | TBD | 14-18 | .438 | - | | MVP Arena · Albany, NY |
| 9 | Sun Dec 7 | atSaint Peter's | 2:00 PM | 12-16 | .429 | - | | Yanitelli Center · Jersey City, NJ |
| 10 | Sat Dec 13 | atMorgan St | TBD | 14-18 | .438 | - | | Hill Field House · Baltimore, MD |
| 11 | Mon Dec 15 | atVCU | TBD | 28-7 | .800 | - | | Stuart C. Siegel Center · Richmond, VA |
| 12 | Sat Dec 20 | vsTBD | TBD | 0-0 | .000 | - | | Gallagher Center · Niagara Falls, NY |
| 13 | Fri Jan 2 | vsSacred Heart | TBD | 15-18 | .455 | - | | Gallagher Center · Niagara Falls, NY |
| 14 | Sun Jan 4 | vsFairfield | TBD | 12-20 | .375 | - | | Gallagher Center · Niagara Falls, NY |
| 15 | Fri Jan 9 | atIona | TBD | 17-17 | .500 | - | | Hynes Athletics Center · New Rochelle, NY |
| 16 | Sun Jan 11 | atManhattan | TBD | 17-14 | .548 | - | | Draddy Gymnasium · Riverdale, NY |
| 17 | Wed Jan 14 | atCanisius | TBD | 3-28 | .097 | - | | Koessler Athletic Center · Buffalo, NY |
| 18 | Mon Jan 19 | vsMount St Mary | TBD | 23-13 | .639 | - | | Gallagher Center · Niagara Falls, NY |
| 19 | Thu Jan 22 | atFairfield | TBD | 12-20 | .375 | - | | Leo D. Mahoney Arena · Fairfield, CT |
| 20 | Sat Jan 24 | atSacred Heart | 12:00 PM | 15-18 | .455 | - | | William H. Pitt Center · Fairfield, CT |
| 21 | Fri Jan 30 | vsSiena | TBD | 14-18 | .438 | - | | Gallagher Center · Niagara Falls, NY |
| 22 | Sun Feb 1 | vsMarist | 2:00 PM | 20-10 | .667 | - | | Gallagher Center · Niagara Falls, NY |
| 23 | Tue Feb 3 | vsCanisius | TBD | 3-28 | .097 | - | | Gallagher Center · Niagara Falls, NY |
| 24 | Sat Feb 7 | atQuinnipiac | 2:00 PM | 20-13 | .606 | - | | M&T Bank Arena · Hamden, CT |
| 25 | Fri Feb 13 | vsManhattan | TBD | 17-14 | .548 | - | | Gallagher Center · Niagara Falls, NY |
| 26 | Sun Feb 15 | vsIona | TBD | 17-17 | .500 | - | | Gallagher Center · Niagara Falls, NY |
| 27 | Fri Feb 20 | atMount St Mary | 7:00 PM | 23-13 | .639 | - | | Knott Arena · Emmitsburg, MD |
| 28 | Sun Feb 22 | atRider | TBD | 14-19 | .424 | - | | Alumni Gymnasium (Rider) · Lawrenceville, NJ |
| 29 | Fri Feb 27 | vsQuinnipiac | TBD | 20-13 | .606 | - | | Gallagher Center · Niagara Falls, NY |
| 30 | Sun Mar 1 | vsMerrimack | TBD | 18-15 | .545 | - | | Gallagher Center · Niagara Falls, NY |
