| 1 | Mon Nov 3 | vs TBD | W101-50 | 1-0 | 1.000 | - | ESPN+ | Gentry Center · Nashville, TN |
| 2 | Sat Nov 8 | atBelmont | L79-87 | 1-1 | .500 | - | ESPN+ | Curb Event Center Arena · Nashville, TN |
| 3 | Tue Nov 11 | vsTBD | W114-76 | 2-1 | .667 | - | ESPN+ | Gentry Center · Nashville, TN |
| 4 | Sun Nov 16 | atWestern KY | L82-95 | 2-2 | .500 | - | ESPN+ | E. A. Diddle Arena · Bowling Green, KY |
| 5 | Thu Nov 20 | at20Tennessee | L60-89 | 2-3 | .400 | - | SECN+ | Thompson-Boling Arena · Knoxville, TN |
| 6 | Tue Nov 25 | atUNC Asheville | W75-73 | 3-3 | .500 | - | ESPN+ | Kimmel Arena · Asheville, NC |
| 7 | Sat Nov 29 | vsTBD | W98-77 | 4-3 | .571 | - | | McKenzie Arena · Chattanooga, TN |
| 8 | Sun Nov 30 | atChattanooga | W70-64 | 5-3 | .625 | - | ESPN+ | McKenzie Arena · Chattanooga, TN |
| 9 | Wed Dec 3 | atAlabama A&M | L53-80 | 5-4 | .556 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 10 | Sat Dec 13 | atUNLV | W63-60 | 6-4 | .600 | - | | Thomas & Mack Center · Las Vegas, NV |
| 11 | Thu Dec 18 | vsUT Martin | W78-71 | 7-4 | .636 | - | ESPN+ | Gentry Center · Nashville, TN |
| 12 | Sat Dec 20 | vsSE Missouri St | L82-91 | 7-5 | .583 | - | ESPN+ | Gentry Center · Nashville, TN |
| 13 | Tue Dec 30 | atTennessee Tech | W88-76 | 8-5 | .615 | - | ESPN+ | Hooper Eblen Center · Cookeville, TN |
| 14 | Sat Jan 3 | atLittle Rock | W84-79 | 9-5 | .643 | - | ESPN+ | Jack Stephens Center · Little Rock, AR |
| 15 | Thu Jan 8 | atW Illinois | W90-68 | 10-5 | .667 | - | ESPN+ | LeRoy A. Ufkes Court at Western Hall · Macomb, IL |
| 16 | Sat Jan 10 | atE Illinois | L70-74 | 10-6 | .625 | - | ESPN+ | Lantz Arena · Charleston, IL |
| 17 | Thu Jan 15 | vsMorehead St | W105-100 (OT) | 11-6 | .647 | - | ESPN+ | Gentry Center · Nashville, TN |
| 18 | Sat Jan 17 | vsSo Indiana | W73-67 | 12-6 | .667 | - | ESPN+ | Gentry Center · Nashville, TN |
| 19 | Thu Jan 22 | atSIUE | L66-74 | 12-7 | .632 | - | ESPNU | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 20 | Sat Jan 24 | atLindenwood | W96-86 | 13-7 | .650 | - | ESPN+ | placeholder · sf, ca |
| 21 | Thu Jan 29 | vsLittle Rock | W70-63 | 14-7 | .667 | - | ESPN+ | Gentry Center · Nashville, TN |
| 22 | Mon Feb 2 | vsTennessee Tech | L85-90 | 14-8 | .636 | - | ESPN+ | Gentry Center · Nashville, TN |
| 23 | Thu Feb 5 | vsE Illinois | W77-68 | 15-8 | .652 | - | ESPN+ | Gentry Center · Nashville, TN |
| 24 | Sat Feb 7 | vsW Illinois | W83-56 | 16-8 | .667 | - | ESPN+ | Gentry Center · Nashville, TN |
| 25 | Thu Feb 12 | atSo Indiana | W73-71 | 17-8 | .680 | - | ESPN+ | Screaming Eagles Arena · Evansville, IN |
| 26 | Sat Feb 14 | atMorehead St | L86-94 | 17-9 | .654 | - | ESPN+ | Ellis T. Johnson Arena · Morehead, KY |
| 27 | Thu Feb 19 | vsLindenwood | W89-80 | 18-9 | .667 | - | ESPN+ | Gentry Center · Nashville, TN |
| 28 | Sat Feb 21 | vsSIUE | W80-53 | 19-9 | .679 | - | ESPNU | Gentry Center · Nashville, TN |
| 29 | Thu Feb 26 | atSE Missouri St | W79-71 | 20-9 | .690 | - | ESPN+ | Show Me Center · Cape Girardeau, MO |
| 30 | Sat Feb 28 | atUT Martin | W67-42 | 21-9 | .700 | - | ESPNU | Kathleen and Tom Elam Center · Martin, TN |
