| 1 | Mon Nov 6 | vs Merrimack | W67-55 | 1-0 | 1.000 | - | | Patrick Gymnasium · Burlington, VT |
| 2 | Sat Nov 11 | vsTBD | W92-41 | 2-0 | 1.000 | - | | Patrick Gymnasium · Burlington, VT |
| 3 | Thu Nov 16 | vsCharleston | W73-64 | 3-0 | 1.000 | - | ESPNU | The HTC Center · Conway, SC |
| 4 | Fri Nov 17 | atSaint Louis | W78-68 | 4-0 | 1.000 | - | ESPN2 | The HTC Center · Conway, SC |
| 5 | Sun Nov 19 | atLiberty | L61-71 | 4-1 | .800 | - | ESPN2 | The HTC Center · Conway, SC |
| 6 | Wed Nov 22 | vsTBD | W106-57 | 5-1 | .833 | - | | Patrick Gymnasium · Burlington, VT |
| 7 | Sat Nov 25 | atBradley | L70-79 | 5-2 | .714 | - | | Carver Arena · Peoria, IL |
| 8 | Wed Nov 29 | vsDartmouth | W64-53 | 6-2 | .750 | - | | Patrick Gymnasium · Burlington, VT |
| 9 | Sat Dec 2 | vsYale | W66-65 | 7-2 | .778 | - | | Patrick Gymnasium · Burlington, VT |
| 10 | Wed Dec 6 | atNortheastern | W73-71 | 8-2 | .800 | - | | Matthews Arena · Boston, MA |
| 11 | Sat Dec 9 | vsColgate | L71-77 | 8-3 | .727 | - | | Patrick Gymnasium · Burlington, VT |
| 12 | Sat Dec 16 | atVirginia Tech | L51-73 | 8-4 | .667 | - | ACC Network | Cassell Coliseum · Blacksburg, VA |
| 13 | Wed Dec 20 | atToledo | W86-60 | 9-4 | .692 | - | | Savage Arena · Toledo, OH |
| 14 | Fri Dec 22 | atMiami OH | L69-70 | 9-5 | .643 | - | | Millett Hall · Oxford, OH |
| 15 | Tue Jan 2 | atBrown | W71-70 | 10-5 | .667 | - | | Pizzitola Sports Center · Providence, RI |
| 16 | Sat Jan 6 | vsMaine | W65-58 | 11-5 | .688 | - | | Patrick Gymnasium · Burlington, VT |
| 17 | Thu Jan 11 | vsUMBC | W77-72 | 12-5 | .706 | - | ESPNU | Patrick Gymnasium · Burlington, VT |
| 18 | Sat Jan 13 | vsNJIT | W76-55 | 13-5 | .722 | - | | Patrick Gymnasium · Burlington, VT |
| 19 | Thu Jan 18 | atBinghamton | W82-62 | 14-5 | .737 | - | | Events Center (Binghamton) · Binghamton, NY |
| 20 | Thu Jan 25 | atUMass Lowell | W72-65 (OT) | 15-5 | .750 | - | | Costello Athletic Center · Lowell, MA |
| 21 | Sat Jan 27 | atBryant | W67-57 | 16-5 | .762 | - | | Chace Athletic Center · Smithfield, RI |
| 22 | Thu Feb 1 | vsAlbany | W81-59 | 17-5 | .773 | - | | Patrick Gymnasium · Burlington, VT |
| 23 | Sat Feb 3 | vsBinghamton | W62-49 | 18-5 | .783 | - | | Patrick Gymnasium · Burlington, VT |
| 24 | Thu Feb 8 | atNJIT | L61-63 | 18-6 | .750 | - | | NJIT Wellness and Events Center · Newark, NJ |
| 25 | Sat Feb 10 | atUMBC | W72-70 | 19-6 | .760 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 26 | Thu Feb 15 | vsNew Hampshire | W70-54 | 20-6 | .769 | - | | Patrick Gymnasium · Burlington, VT |
| 27 | Sat Feb 17 | atMaine | W68-57 | 21-6 | .778 | - | | Cross Insurance Center · Bangor, ME |
| 28 | Thu Feb 22 | atAlbany | W94-80 | 22-6 | .786 | - | | SEFCU Arena · Albany, NY |
| 29 | Sat Feb 24 | vsBryant | W65-48 | 23-6 | .793 | - | | Patrick Gymnasium · Burlington, VT |
| 30 | Sat Mar 2 | vsUMass Lowell | W74-62 | 24-6 | .800 | - | | Patrick Gymnasium · Burlington, VT |
| 31 | Tue Mar 5 | atNew Hampshire | W68-64 | 25-6 | .806 | - | | Lundholm Gymnasium · Durham, NH |
| 32 | Sat Mar 9 | vsAlbany | W75-72 | 26-6 | .813 | - | | Patrick Gymnasium · Burlington, VT |
| 33 | Tue Mar 12 | vsNew Hampshire | W66-59 | 27-6 | .818 | - | ESPN2 | Patrick Gymnasium · Burlington, VT |
| 34 | Sat Mar 16 | vsUMass Lowell | W66-61 | 28-6 | .824 | - | ESPN2 | Patrick Gymnasium · Burlington, VT |
| 35 | Fri Mar 22 | at4Duke | L47-64 | 28-7 | .800 | #13 | CBS | Cameron Indoor Stadium · Durham, NC |
