| 1 | Thu Oct 10 | at Predators | W4-3 | 1-0-0 | 2 PTS | Bridgestone Arena · Nashville, TN |
| 2 | Sat Oct 12 | vs Islanders | W3-0 | 2-0-0 | 4 PTS | American Airlines Center · Dallas, TX |
| 3 | Sun Oct 13 | vs Kraken | W2-0 | 3-0-0 | 6 PTS | American Airlines Center · Dallas, TX |
| 4 | Tue Oct 15 | vs Sharks | W3-2 (SO) | 4-0-0 | 8 PTS | American Airlines Center · Dallas, TX |
| 5 | Thu Oct 17 | at Capitals | L2-3 | 4-1-0 | 8 PTS | Capital One Arena · Washington, D.C. |
| 6 | Sat Oct 19 | vs Oilers | W4-1 | 5-1-0 | 10 PTS | American Airlines Center · Dallas, TX |
| 7 | Tue Oct 22 | at Sabres | L2-4 | 5-2-0 | 10 PTS | KeyBank Center · Buffalo, NY |
| 8 | Thu Oct 24 | at Bruins | W5-2 | 6-2-0 | 12 PTS | TD Garden · Boston, MA |
| 9 | Sat Oct 26 | vs Blackhawks | W4-2 | 7-2-0 | 14 PTS | American Airlines Center · Dallas, TX |
| 10 | Fri Nov 1 | vs Panthers | L4-6 | 7-3-0 | 14 PTS | American Airlines Center · Dallas, TX |
| 11 | Sat Nov 2 | atPanthers | L2-4 | 7-4-0 | 14 PTS | Amerant Bank Arena · Sunrise, FL |
| 12 | Thu Nov 7 | vsBlackhawks | W3-1 | 8-4-0 | 16 PTS | American Airlines Center · Dallas, TX |
| 13 | Sat Nov 9 | at Jets | L1-4 | 8-5-0 | 16 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 14 | Mon Nov 11 | at Penguins | W7-1 | 9-5-0 | 18 PTS | PPG Paints Arena · Pittsburgh, PA |
| 15 | Thu Nov 14 | vsBruins | W7-2 | 10-5-0 | 20 PTS | American Airlines Center · Dallas, TX |
| 16 | Sat Nov 16 | at Wild | W2-1 | 11-5-0 | 22 PTS | Xcel Energy Center · St. Paul, MN |
| 17 | Mon Nov 18 | vs Ducks | L2-4 | 11-6-0 | 22 PTS | American Airlines Center · Dallas, TX |
| 18 | Wed Nov 20 | vsSharks | W5-2 | 12-6-0 | 24 PTS | American Airlines Center · Dallas, TX |
| 19 | Sat Nov 23 | at Lightning | W4-2 | 13-6-0 | 26 PTS | AMALIE Arena · Tampa, FL |
| 20 | Mon Nov 25 | at Hurricanes | L4-6 | 13-7-0 | 26 PTS | PNC Arena · Raleigh, NC |
| 21 | Wed Nov 27 | atBlackhawks | L2-6 | 13-8-0 | 26 PTS | United Center · Chicago, IL |
| 22 | Fri Nov 29 | vs Avalanche | W5-3 | 14-8-0 | 28 PTS | American Airlines Center · Dallas, TX |
| 23 | Sun Dec 1 | vsJets | W3-1 | 15-8-0 | 30 PTS | American Airlines Center · Dallas, TX |
| 24 | Mon Dec 2 | at Utah HC | W2-1 | 16-8-0 | 32 PTS | Delta Center · Salt Lake City, UT |
| 25 | Wed Dec 4 | at Kings | L2-3 | 16-9-0 | 32 PTS | Crypto.com Arena · Los Angeles, CA |
| 26 | Fri Dec 6 | at Knights | L2-3 | 16-10-0 | 32 PTS | T-Mobile Arena · Las Vegas, NV |
| 27 | Sun Dec 8 | vs Flames | W6-2 | 17-10-0 | 34 PTS | American Airlines Center · Dallas, TX |
| 28 | Thu Dec 12 | vsPredators | L1-4 | 17-11-0 | 34 PTS | American Airlines Center · Dallas, TX |
| 29 | Sat Dec 14 | vs Blues | W2-1 (OT) | 18-11-0 | 36 PTS | American Airlines Center · Dallas, TX |
| 30 | Mon Dec 16 | vsCapitals | W3-1 | 19-11-0 | 38 PTS | American Airlines Center · Dallas, TX |
| 31 | Wed Dec 18 | vs Maple Leafs | L3-5 | 19-12-0 | 38 PTS | American Airlines Center · Dallas, TX |
| 32 | Fri Dec 20 | vs Rangers | L1-3 | 19-13-0 | 38 PTS | American Airlines Center · Dallas, TX |
| 33 | Mon Dec 23 | atUtah HC | W3-2 | 20-13-0 | 40 PTS | Delta Center · Salt Lake City, UT |
| 34 | Fri Dec 27 | vsWild | L2-3 (OT) | 20-13-1 | 41 PTS | American Airlines Center · Dallas, TX |
| 35 | Sun Dec 29 | atBlackhawks | W5-1 | 21-13-1 | 43 PTS | United Center · Chicago, IL |
| 36 | Tue Dec 31 | vsSabres | W4-2 | 22-13-1 | 45 PTS | American Airlines Center · Dallas, TX |
| 37 | Thu Jan 2 | vs Senators | W4-2 | 23-13-1 | 47 PTS | American Airlines Center · Dallas, TX |
| 38 | Sat Jan 4 | vsUtah HC | W3-2 (OT) | 24-13-1 | 49 PTS | American Airlines Center · Dallas, TX |
| 39 | Tue Jan 7 | atRangers | W5-4 (OT) | 25-13-1 | 51 PTS | Madison Square Garden · Manhattan, NY |
| 40 | Thu Jan 9 | at Flyers | W4-1 | 26-13-1 | 53 PTS | Wells Fargo Center · Philadelphia, PA |
| 41 | Sat Jan 11 | at Canadiens | W2-1 (SO) | 27-13-1 | 55 PTS | Bell Centre · Montreal, QC |
| 42 | Sun Jan 12 | atSenators | L2-3 | 27-14-1 | 55 PTS | Canadian Tire Centre · Ottawa, ON |
| 43 | Tue Jan 14 | atMaple Leafs | W4-1 | 28-14-1 | 57 PTS | Scotiabank Arena · Toronto, ON |
| 44 | Thu Jan 16 | vsCanadiens | L1-3 | 28-15-1 | 57 PTS | American Airlines Center · Dallas, TX |
| 45 | Sat Jan 18 | atAvalanche | L3-6 | 28-16-1 | 57 PTS | Ball Arena · Denver, CO |
| 46 | Sun Jan 19 | vs Red Wings | W4-1 | 29-16-1 | 59 PTS | American Airlines Center · Dallas, TX |
| 47 | Tue Jan 21 | vsHurricanes | L1-2 | 29-17-1 | 59 PTS | American Airlines Center · Dallas, TX |
| 48 | Fri Jan 24 | vsKnights | W4-3 | 30-17-1 | 61 PTS | American Airlines Center · Dallas, TX |
| 49 | Sat Jan 25 | atBlues | W2-0 | 31-17-1 | 63 PTS | Enterprise Center · St. Louis, MO |
| 50 | Tue Jan 28 | atKnights | W4-3 (OT) | 32-17-1 | 65 PTS | T-Mobile Arena · Las Vegas, NV |
| 51 | Fri Jan 31 | vs Canucks | W5-3 | 33-17-1 | 67 PTS | American Airlines Center · Dallas, TX |
| 52 | Sun Feb 2 | vs Jackets | W5-3 | 34-17-1 | 69 PTS | American Airlines Center · Dallas, TX |
| 53 | Tue Feb 4 | atDucks | L1-2 | 34-18-1 | 69 PTS | Honda Center · Anaheim, CA |
| 54 | Fri Feb 7 | atKings | L4-5 (SO) | 34-18-2 | 70 PTS | Crypto.com Arena · Los Angeles, CA |
| 55 | Sat Feb 8 | atSharks | W8-3 | 35-18-2 | 72 PTS | SAP Center · San Jose, CA |
Devils