| 1 | Thu Oct 10 | vs Blues | L4-5 (OT) | 0-0-1 | 1 PTS | SAP Center · San Jose, CA |
| 2 | Sat Oct 12 | vs Ducks | L0-2 | 0-1-1 | 1 PTS | SAP Center · San Jose, CA |
| 3 | Tue Oct 15 | at Stars | L2-3 (SO) | 0-1-2 | 2 PTS | American Airlines Center · Dallas, TX |
| 4 | Thu Oct 17 | at Blackhawks | L2-4 | 0-2-2 | 2 PTS | United Center · Chicago, IL |
| 5 | Fri Oct 18 | at Jets | L3-8 | 0-3-2 | 2 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 6 | Sun Oct 20 | vs Avalanche | L1-4 | 0-4-2 | 2 PTS | SAP Center · San Jose, CA |
| 7 | Tue Oct 22 | atDucks | L1-3 | 0-5-2 | 2 PTS | Honda Center · Anaheim, CA |
| 8 | Thu Oct 24 | at Kings | L2-3 | 0-6-2 | 2 PTS | Crypto.com Arena · Los Angeles, CA |
| 9 | Sat Oct 26 | at Knights | L3-7 | 0-7-2 | 2 PTS | T-Mobile Arena · Las Vegas, NV |
| 10 | Mon Oct 28 | at Utah HC | W5-4 (OT) | 1-7-2 | 4 PTS | Delta Center · Salt Lake City, UT |
| 11 | Tue Oct 29 | vsKings | W4-2 | 2-7-2 | 6 PTS | SAP Center · San Jose, CA |
| 12 | Thu Oct 31 | vsBlackhawks | W3-2 | 3-7-2 | 8 PTS | SAP Center · San Jose, CA |
| 13 | Sat Nov 2 | vs Canucks | L2-3 | 3-8-2 | 8 PTS | SAP Center · San Jose, CA |
| 14 | Tue Nov 5 | vs Jackets | W2-1 (OT) | 4-8-2 | 10 PTS | SAP Center · San Jose, CA |
| 15 | Thu Nov 7 | vs Wild | L2-5 | 4-9-2 | 10 PTS | SAP Center · San Jose, CA |
| 16 | Sun Nov 10 | at Devils | W1-0 | 5-9-2 | 12 PTS | Prudential Center · Newark, NJ |
| 17 | Mon Nov 11 | at Flyers | L3-4 (SO) | 5-9-3 | 13 PTS | Wells Fargo Center · Philadelphia, PA |
| 18 | Thu Nov 14 | at Rangers | L2-3 | 5-10-3 | 13 PTS | Madison Square Garden · Manhattan, NY |
| 19 | Sat Nov 16 | at Penguins | L3-4 (SO) | 5-10-4 | 14 PTS | PPG Paints Arena · Pittsburgh, PA |
| 20 | Mon Nov 18 | vs Red Wings | W5-4 (OT) | 6-10-4 | 16 PTS | SAP Center · San Jose, CA |
| 21 | Wed Nov 20 | atStars | L2-5 | 6-11-4 | 16 PTS | American Airlines Center · Dallas, TX |
| 22 | Thu Nov 21 | atBlues | L2-3 (SO) | 6-11-5 | 17 PTS | Enterprise Center · St. Louis, MO |
| 23 | Sat Nov 23 | vs Sabres | L2-4 | 6-12-5 | 17 PTS | SAP Center · San Jose, CA |
| 24 | Mon Nov 25 | vsKings | W7-2 | 7-12-5 | 19 PTS | SAP Center · San Jose, CA |
| 25 | Wed Nov 27 | vs Senators | L3-4 | 7-13-5 | 19 PTS | SAP Center · San Jose, CA |
| 26 | Fri Nov 29 | vs Kraken | W8-5 | 8-13-5 | 21 PTS | SAP Center · San Jose, CA |
| 27 | Sat Nov 30 | atKraken | W4-2 | 9-13-5 | 23 PTS | Climate Pledge Arena · Seattle, WA |
| 28 | Tue Dec 3 | at Capitals | W2-1 (OT) | 10-13-5 | 25 PTS | Capital One Arena · Washington, D.C. |
| 29 | Thu Dec 5 | at Lightning | L1-8 | 10-14-5 | 25 PTS | AMALIE Arena · Tampa, FL |
| 30 | Sat Dec 7 | at Panthers | L1-3 | 10-15-5 | 25 PTS | Amerant Bank Arena · Sunrise, FL |
| 31 | Tue Dec 10 | at Hurricanes | L2-3 | 10-16-5 | 25 PTS | PNC Arena · Raleigh, NC |
| 32 | Thu Dec 12 | atBlues | W4-3 | 11-16-5 | 27 PTS | Enterprise Center · St. Louis, MO |
| 33 | Sat Dec 14 | vsUtah HC | L3-4 | 11-17-5 | 27 PTS | SAP Center · San Jose, CA |
| 34 | Tue Dec 17 | vsJets | L3-4 | 11-18-5 | 27 PTS | SAP Center · San Jose, CA |
| 35 | Thu Dec 19 | vsAvalanche | L2-4 | 11-19-5 | 27 PTS | SAP Center · San Jose, CA |
| 36 | Sat Dec 21 | at Oilers | L2-3 (OT) | 11-19-6 | 28 PTS | Rogers Place · Edmonton, AB |
| 37 | Mon Dec 23 | atCanucks | L3-4 | 11-20-6 | 28 PTS | Rogers Arena · Vancouver, British Columbia |
| 38 | Fri Dec 27 | vsKnights | L3-6 | 11-21-6 | 28 PTS | SAP Center · San Jose, CA |
| 39 | Sat Dec 28 | vs Flames | L1-3 | 11-22-6 | 28 PTS | SAP Center · San Jose, CA |
| 40 | Tue Dec 31 | vsFlyers | L0-4 | 11-23-6 | 28 PTS | SAP Center · San Jose, CA |
| 41 | Thu Jan 2 | vsLightning | W2-1 | 12-23-6 | 30 PTS | SAP Center · San Jose, CA |
| 42 | Sat Jan 4 | vsDevils | W3-2 | 13-23-6 | 32 PTS | SAP Center · San Jose, CA |
| 43 | Tue Jan 7 | vsKnights | L2-4 | 13-24-6 | 32 PTS | SAP Center · San Jose, CA |
| 44 | Fri Jan 10 | atUtah HC | L1-2 | 13-25-6 | 32 PTS | Delta Center · Salt Lake City, UT |
| 45 | Sat Jan 11 | vsWild | L1-3 | 13-26-6 | 32 PTS | SAP Center · San Jose, CA |
| 46 | Tue Jan 14 | atRed Wings | W6-3 | 14-26-6 | 34 PTS | Little Caesars Arena · Detroit, MI |
| 47 | Thu Jan 16 | atJackets | L1-4 | 14-27-6 | 34 PTS | Nationwide Arena · Columbus, OH |
| 48 | Sat Jan 18 | at Islanders | L1-4 | 14-28-6 | 34 PTS | UBS Arena · Elmont, NY |
| 49 | Mon Jan 20 | at Bruins | L3-6 | 14-29-6 | 34 PTS | TD Garden · Boston, MA |
| 50 | Tue Jan 21 | at Predators | L5-7 | 14-30-6 | 34 PTS | Bridgestone Arena · Nashville, TN |
| 51 | Thu Jan 23 | vsPredators | L5-6 | 14-31-6 | 34 PTS | SAP Center · San Jose, CA |
| 52 | Sat Jan 25 | vsPanthers | L2-7 | 14-32-6 | 34 PTS | SAP Center · San Jose, CA |
| 53 | Mon Jan 27 | vsPenguins | W2-1 | 15-32-6 | 36 PTS | SAP Center · San Jose, CA |
| 54 | Thu Jan 30 | atKraken | L2-6 | 15-33-6 | 36 PTS | Climate Pledge Arena · Seattle, WA |
| 55 | Tue Feb 4 | vs Canadiens | L3-4 | 15-34-6 | 36 PTS | SAP Center · San Jose, CA |
| 56 | Thu Feb 6 | vsCanucks | L1-2 (OT) | 15-34-7 | 37 PTS | SAP Center · San Jose, CA |
| 57 | Sat Feb 8 | vsStars | L3-8 | 15-35-7 | 37 PTS | SAP Center · San Jose, CA |
| 58 | Sun Feb 23 | atFlames | L2-3 | 15-36-7 | 37 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 59 | Mon Feb 24 | atJets | L1-2 (OT) | 15-36-8 | 38 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 60 | Thu Feb 27 | atCanadiens | L3-4 (OT) | 15-36-9 | 39 PTS | Bell Centre · Montreal, QC |
| 61 | Sat Mar 1 | atSenators | L3-5 | 15-37-9 | 39 PTS | Canadian Tire Centre · Ottawa, ON |
| 62 | Mon Mar 3 | at Maple Leafs | W3-2 (SO) | 16-37-9 | 41 PTS | Scotiabank Arena · Toronto, ON |
| 63 | Tue Mar 4 | atSabres | W6-2 | 17-37-9 | 43 PTS | KeyBank Center · Buffalo, NY |
| 64 | Thu Mar 6 | atAvalanche | L3-7 | 17-38-9 | 43 PTS | Ball Arena · Denver, CO |
| 65 | Sat Mar 8 | vsIslanders | L2-4 | 17-39-9 | 43 PTS | SAP Center · San Jose, CA |
| 66 | Tue Mar 11 | vsPredators | L2-3 | 17-40-9 | 43 PTS | SAP Center · San Jose, CA |
| 67 | Thu Mar 13 | vsBlackhawks | W4-2 | 18-40-9 | 45 PTS | SAP Center · San Jose, CA |
| 68 | Sat Mar 15 | vsCapitals | L1-5 | 18-41-9 | 45 PTS | SAP Center · San Jose, CA |
| 69 | Thu Mar 20 | vsHurricanes | L1-3 | 18-42-9 | 45 PTS | SAP Center · San Jose, CA |
| 70 | Sat Mar 22 | vsBruins | W3-1 | 19-42-9 | 47 PTS | SAP Center · San Jose, CA |
