| 1 | Sat Oct 16 | vs Jets | W4-3 | 1-0-0 | 2 PTS | SAP Center · San Jose, CA |
| 2 | Tue Oct 19 | atCanadiens | W5-0 | 2-0-0 | 4 PTS | Bell Centre · Montreal, QC |
| 3 | Thu Oct 21 | atSenators | W2-1 | 3-0-0 | 6 PTS | Canadian Tire Centre · Ottawa, ON |
| 4 | Fri Oct 22 | atMaple Leafs | W5-3 | 4-0-0 | 8 PTS | Scotiabank Arena · Toronto, ON |
| 5 | Sun Oct 24 | atBruins | L3-4 | 4-1-0 | 8 PTS | TD Garden · Boston, MA |
| 6 | Tue Oct 26 | atPredators | L1-3 | 4-2-0 | 8 PTS | Bridgestone Arena · Nashville, TN |
| 7 | Thu Oct 28 | vsCanadiens | L0-4 | 4-3-0 | 8 PTS | SAP Center · San Jose, CA |
| 8 | Sat Oct 30 | vsJets | W2-1 (OT) | 5-3-0 | 10 PTS | SAP Center · San Jose, CA |
| 9 | Tue Nov 2 | vsSabres | W5-3 | 6-3-0 | 12 PTS | SAP Center · San Jose, CA |
| 10 | Thu Nov 4 | vsBlues | L3-5 | 6-4-0 | 12 PTS | SAP Center · San Jose, CA |
| 11 | Sat Nov 6 | vsDevils | L2-3 (SO) | 6-4-1 | 13 PTS | SAP Center · San Jose, CA |
| 12 | Tue Nov 9 | atFlames | W4-1 | 7-4-1 | 15 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 13 | Thu Nov 11 | atJets | L1-4 | 7-5-1 | 15 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 14 | Sat Nov 13 | atAvalanche | L2-6 | 7-6-1 | 15 PTS | Ball Arena · Denver, CO |
| 15 | Tue Nov 16 | atWild | W4-1 | 8-6-1 | 17 PTS | Xcel Energy Center · St. Paul, MN |
| 16 | Thu Nov 18 | atBlues | L1-4 | 8-7-1 | 17 PTS | Enterprise Center · St. Louis, MO |
| 17 | Sat Nov 20 | vsCapitals | L0-4 | 8-8-1 | 17 PTS | SAP Center · San Jose, CA |
| 18 | Mon Nov 22 | vsHurricanes | W2-1 (OT) | 9-8-1 | 19 PTS | SAP Center · San Jose, CA |
| 19 | Wed Nov 24 | vsSenators | W6-3 | 10-8-1 | 21 PTS | SAP Center · San Jose, CA |
| 20 | Fri Nov 26 | vsMaple Leafs | L1-4 | 10-9-1 | 21 PTS | SAP Center · San Jose, CA |
| 21 | Sun Nov 28 | atBlackhawks | W2-0 | 11-9-1 | 23 PTS | United Center · Chicago, IL |
| 22 | Tue Nov 30 | atDevils | W5-2 | 12-9-1 | 25 PTS | Prudential Center · Newark, NJ |
| 23 | Thu Dec 2 | atIslanders | W2-1 (OT) | 13-9-1 | 27 PTS | UBS Arena · Elmont, NY |
| 24 | Fri Dec 3 | atRangers | L0-1 | 13-10-1 | 27 PTS | Madison Square Garden · Manhattan, NY |
| 25 | Sun Dec 5 | atJackets | L4-6 | 13-11-1 | 27 PTS | Nationwide Arena · Columbus, OH |
| 26 | Tue Dec 7 | vsFlames | W5-3 | 14-11-1 | 29 PTS | SAP Center · San Jose, CA |
| 27 | Thu Dec 9 | vsWild | L2-5 | 14-12-1 | 29 PTS | SAP Center · San Jose, CA |
| 28 | Sat Dec 11 | vsStars | W2-1 | 15-12-1 | 31 PTS | SAP Center · San Jose, CA |
| 29 | Tue Dec 14 | vsKraken | L1-3 | 15-13-1 | 31 PTS | SAP Center · San Jose, CA |
| 30 | Thu Dec 16 | vsCanucks | L2-5 | 15-14-1 | 31 PTS | SAP Center · San Jose, CA |
| 31 | Tue Dec 28 | vsCoyotes | W8-7 (SO) | 16-14-1 | 33 PTS | SAP Center · San Jose, CA |
| 32 | Thu Dec 30 | vsFlyers | W3-2 (OT) | 17-14-1 | 35 PTS | SAP Center · San Jose, CA |
| 33 | Sun Jan 2 | atPenguins | L5-8 | 17-15-1 | 35 PTS | PPG Paints Arena · Pittsburgh, PA |
| 34 | Tue Jan 4 | atRed Wings | L2-6 | 17-16-1 | 35 PTS | Little Caesars Arena · Detroit, MI |
| 35 | Thu Jan 6 | atSabres | W3-2 | 18-16-1 | 37 PTS | KeyBank Center · Buffalo, NY |
| 36 | Sat Jan 8 | atFlyers | W3-2 (OT) | 19-16-1 | 39 PTS | Wells Fargo Center · Philadelphia, PA |
| 37 | Tue Jan 11 | vsRed Wings | W3-2 (OT) | 20-16-1 | 41 PTS | SAP Center · San Jose, CA |
| 38 | Thu Jan 13 | vsRangers | L0-3 | 20-17-1 | 41 PTS | SAP Center · San Jose, CA |
| 39 | Sat Jan 15 | vsPenguins | L1-2 (OT) | 20-17-2 | 42 PTS | SAP Center · San Jose, CA |
| 40 | Mon Jan 17 | vsKings | W6-2 | 21-17-2 | 44 PTS | SAP Center · San Jose, CA |
| 41 | Thu Jan 20 | atKraken | L2-3 | 21-18-2 | 44 PTS | Climate Pledge Arena · Seattle, WA |
| 42 | Sat Jan 22 | vsLightning | L1-7 | 21-19-2 | 44 PTS | SAP Center · San Jose, CA |
| 43 | Wed Jan 26 | atCapitals | W4-1 | 22-19-2 | 46 PTS | Capital One Arena · Washington, D.C. |
| 44 | Sat Jan 29 | atPanthers | L4-5 (OT) | 22-19-3 | 47 PTS | Amerant Bank Arena · Sunrise, FL |
| 45 | Sun Jan 30 | atHurricanes | L1-2 | 22-20-3 | 47 PTS | PNC Arena · Raleigh, NC |
| 46 | Tue Feb 1 | atLightning | L2-3 (OT) | 22-20-4 | 48 PTS | AMALIE Arena · Tampa, FL |
| 47 | Mon Feb 14 | vsOilers | L0-3 | 22-21-4 | 48 PTS | SAP Center · San Jose, CA |
| 48 | Thu Feb 17 | vsCanucks | L4-5 (OT) | 22-21-5 | 49 PTS | SAP Center · San Jose, CA |
| 49 | Sun Feb 20 | vsKnights | L1-4 | 22-22-5 | 49 PTS | SAP Center · San Jose, CA |
| 50 | Tue Feb 22 | atDucks | L3-4 (SO) | 22-22-6 | 50 PTS | Honda Center · Anaheim, CA |
| 51 | Thu Feb 24 | vsIslanders | W4-3 (SO) | 23-22-6 | 52 PTS | SAP Center · San Jose, CA |
| 52 | Sat Feb 26 | vsBruins | L1-3 | 23-23-6 | 52 PTS | SAP Center · San Jose, CA |
| 53 | Sun Feb 27 | vsKraken | W3-1 | 24-23-6 | 54 PTS | SAP Center · San Jose, CA |
| 54 | Tue Mar 1 | atKnights | L1-3 | 24-24-6 | 54 PTS | T-Mobile Arena · Las Vegas, NV |
| 55 | Sat Mar 5 | vsPredators | L0-8 | 24-25-6 | 54 PTS | SAP Center · San Jose, CA |
| 56 | Sun Mar 6 | atDucks | L2-3 (OT) | 24-25-7 | 55 PTS | Honda Center · Anaheim, CA |
| 57 | Thu Mar 10 | atKings | W4-3 (OT) | 25-25-7 | 57 PTS | Crypto.com Arena · Los Angeles, CA |
| 58 | Sat Mar 12 | vsKings | W5-0 | 26-25-7 | 59 PTS | SAP Center · San Jose, CA |
| 59 | Tue Mar 15 | vsPanthers | L2-3 (OT) | 26-25-8 | 60 PTS | SAP Center · San Jose, CA |
| 60 | Thu Mar 17 | atKings | L0-3 | 26-26-8 | 60 PTS | Crypto.com Arena · Los Angeles, CA |
| 61 | Fri Mar 18 | vsAvalanche | L3-5 | 26-27-8 | 60 PTS | SAP Center · San Jose, CA |
| 62 | Sun Mar 20 | vsCoyotes | W4-2 | 27-27-8 | 62 PTS | SAP Center · San Jose, CA |
| 63 | Tue Mar 22 | atFlames | W4-3 | 28-27-8 | 64 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 64 | Thu Mar 24 | atOilers | L2-5 | 28-28-8 | 64 PTS | Rogers Place · Edmonton, AB |
| 65 | Sat Mar 26 | vsDucks | W4-1 | 29-28-8 | 66 PTS | SAP Center · San Jose, CA |
| 66 | Wed Mar 30 | atCoyotes | L2-5 | 29-29-8 | 66 PTS | Mullett Arena · Tempe, AZ |
| 67 | Thu Mar 31 | atAvalanche | L2-4 | 29-30-8 | 66 PTS | Ball Arena · Denver, CO |
| 68 | Sat Apr 2 | vsStars | L4-5 | 29-31-8 | 66 PTS | SAP Center · San Jose, CA |
| 69 | Tue Apr 5 | vsOilers | L1-2 (OT) | 29-31-9 | 67 PTS | SAP Center · San Jose, CA |
| 70 | Thu Apr 7 | vsFlames | L2-4 | 29-32-9 | 67 PTS | SAP Center · San Jose, CA |
| 71 | Sat Apr 9 | atCanucks | L2-4 | 29-33-9 | 67 PTS | Rogers Arena · Vancouver, British Columbia |
| 72 | Tue Apr 12 | atPredators | L0-1 (OT) | 29-33-10 | 68 PTS | Bridgestone Arena · Nashville, TN |
| 73 | Thu Apr 14 | atBlackhawks | L4-5 (SO) | 29-33-11 | 69 PTS | United Center · Chicago, IL |
| 74 | Sat Apr 16 | atStars | L1-2 | 29-34-11 | 69 PTS | American Airlines Center · Dallas, TX |
| 75 | Sun Apr 17 | atWild | L4-5 (OT) | 29-34-12 | 70 PTS | Xcel Energy Center · St. Paul, MN |
| 76 | Tue Apr 19 | vsJackets | W3-2 | 30-34-12 | 72 PTS | SAP Center · San Jose, CA |
| 77 | Thu Apr 21 | vsBlues | L1-3 | 30-35-12 | 72 PTS | SAP Center · San Jose, CA |
| 78 | Sat Apr 23 | vsBlackhawks | W4-1 | 31-35-12 | 74 PTS | SAP Center · San Jose, CA |
| 79 | Sun Apr 24 | atKnights | W5-4 (SO) | 32-35-12 | 76 PTS | T-Mobile Arena · Las Vegas, NV |
| 80 | Tue Apr 26 | vsDucks | L2-5 | 32-36-12 | 76 PTS | SAP Center · San Jose, CA |
| 81 | Thu Apr 28 | atOilers | L4-5 (OT) | 32-36-13 | 77 PTS | Rogers Place · Edmonton, AB |
| 82 | Fri Apr 29 | atKraken | L0-3 | 32-37-13 | 77 PTS | Climate Pledge Arena · Seattle, WA |
