| 1 | Thu Mar 26 | vs Twins | W2-1 | 1-0 | 1.000 | Camden Yards · Baltimore, MD |
| 2 | Sat Mar 28 | vs Twins | L1-4 | 1-1 | .500 | Camden Yards · Baltimore, MD |
| 3 | Sun Mar 29 | vs Twins | W8-6 | 2-1 | .667 | Camden Yards · Baltimore, MD |
| 4 | Mon Mar 30 | vs Rangers | L2-5 | 2-2 | .500 | Camden Yards · Baltimore, MD |
| 5 | Tue Mar 31 | vs Rangers | L5-8 | 2-3 | .400 | Camden Yards · Baltimore, MD |
| 6 | Wed Apr 1 | vs Rangers | W8-3 | 3-3 | .500 | Camden Yards · Baltimore, MD |
| 7 | Fri Apr 3 | at Pirates | L4-5 | 3-4 | .429 | PNC Park · Pittsburgh, PA |
| 8 | Sat Apr 4 | at Pirates | L2-3 | 3-5 | .375 | PNC Park · Pittsburgh, PA |
| 9 | Sun Apr 5 | at Pirates | L2-8 | 3-6 | .333 | PNC Park · Pittsburgh, PA |
| 10 | Mon Apr 6 | at White Sox | W2-1 | 4-6 | .400 | Guaranteed Rate Field · Chicago, IL |
| 11 | Tue Apr 7 | at White Sox | W4-2 | 5-6 | .455 | Guaranteed Rate Field · Chicago, IL |
| 12 | Wed Apr 8 | at White Sox | W5-3 | 6-6 | .500 | Guaranteed Rate Field · Chicago, IL |
| 13 | Fri Apr 10 | vs Giants | L3-6 | 6-7 | .462 | Camden Yards · Baltimore, MD |
| 14 | Sat Apr 11 | vs Giants | W6-2 | 7-7 | .500 | Camden Yards · Baltimore, MD |
| 15 | Sun Apr 12 | vs Giants | W6-2 | 8-7 | .533 | Camden Yards · Baltimore, MD |
| 16 | Mon Apr 13 | vs D-backs | W9-7 | 9-7 | .563 | Camden Yards · Baltimore, MD |
| 17 | Tue Apr 14 | vs D-backs | L3-4 | 9-8 | .529 | Camden Yards · Baltimore, MD |
| 18 | Wed Apr 15 | vs D-backs | L5-8 (10) | 9-9 | .500 | Camden Yards · Baltimore, MD |
| 19 | Thu Apr 16 | at Guardians | L2-4 | 9-10 | .474 | Progressive Field · Cleveland, OH |
| 20 | Fri Apr 17 | at Guardians | W6-4 | 10-10 | .500 | Progressive Field · Cleveland, OH |
| 21 | Sat Apr 18 | at Guardians | L2-4 | 10-11 | .476 | Progressive Field · Cleveland, OH |
| 22 | Sun Apr 19 | at Guardians | L4-8 | 10-12 | .455 | Progressive Field · Cleveland, OH |
| 23 | Mon Apr 20 | at Royals | W7-5 (12) | 11-12 | .478 | Kauffman Stadium · Kansas City, MO |
| 24 | Tue Apr 21 | at Royals | L5-6 | 11-13 | .458 | Kauffman Stadium · Kansas City, MO |
| 25 | Wed Apr 22 | at Royals | W8-6 | 12-13 | .480 | Kauffman Stadium · Kansas City, MO |
| 26 | Fri Apr 24 | vs Red Sox | W10-3 | 13-13 | .500 | Camden Yards · Baltimore, MD |
| 27 | Sat Apr 25 | vs Red Sox | L1-17 | 13-14 | .481 | Camden Yards · Baltimore, MD |
| 28 | Sun Apr 26 | vs Red Sox | L3-5 | 13-15 | .464 | Camden Yards · Baltimore, MD |
| 29 | Tue Apr 28 | vs Astros | W5-3 | 14-15 | .483 | Camden Yards · Baltimore, MD |
| 30 | Thu Apr 30 | vs Astros | W10-3 | 15-15 | .500 | Camden Yards · Baltimore, MD |
| 31 | Thu Apr 30 | vs Astros | L5-11 | 15-16 | .484 | Camden Yards · Baltimore, MD |
| 32 | Fri May 1 | at Yankees | L2-7 | 15-17 | .469 | Yankee Stadium · The Bronx, NY |
| 33 | Sat May 2 | at Yankees | L4-9 | 15-18 | .455 | Yankee Stadium · The Bronx, NY |
| 34 | Sun May 3 | at Yankees | L3-11 | 15-19 | .441 | Yankee Stadium · The Bronx, NY |
| 35 | Mon May 4 | at Yankees | L1-12 | 15-20 | .429 | Yankee Stadium · The Bronx, NY |
| 36 | Tue May 5 | at Marlins | W9-7 | 16-20 | .444 | LoanDepot Park · Miami, FL |
| 37 | Wed May 6 | at Marlins | W7-4 | 17-20 | .459 | LoanDepot Park · Miami, FL |
| 38 | Thu May 7 | at Marlins | L3-4 | 17-21 | .447 | LoanDepot Park · Miami, FL |
| 39 | Fri May 8 | vs Athletics | L3-4 | 17-22 | .436 | Camden Yards · Baltimore, MD |
| 40 | Sat May 9 | vs Athletics | L2-6 | 17-23 | .425 | Camden Yards · Baltimore, MD |
| 41 | Sun May 10 | vs Athletics | W2-1 | 18-23 | .439 | Camden Yards · Baltimore, MD |
| 42 | Mon May 11 | vs Yankees | W3-2 | 19-23 | .452 | Camden Yards · Baltimore, MD |
| 43 | Tue May 12 | vs Yankees | L2-6 | 19-24 | .442 | Camden Yards · Baltimore, MD |
| 44 | Wed May 13 | vs Yankees | W7-0 | 20-24 | .455 | Camden Yards · Baltimore, MD |
| 45 | Fri May 15 | at Nationals | L2-3 | 20-25 | .444 | Nationals Park · Washington, D.C. |
| 46 | Sat May 16 | at Nationals | L3-13 | 20-26 | .435 | Nationals Park · Washington, D.C. |
| 47 | Sun May 17 | at Nationals | W7-3 | 21-26 | .447 | Nationals Park · Washington, D.C. |
| 48 | Mon May 18 | at Rays | L6-16 | 21-27 | .438 | Tropicana Field · St. Petersburg, FL |
| 49 | Tue May 19 | at Rays | L1-4 | 21-28 | .429 | Tropicana Field · St. Petersburg, FL |
| 50 | Wed May 20 | at Rays | L3-5 | 21-29 | .420 | Tropicana Field · St. Petersburg, FL |
| 51 | Fri May 22 | vs Tigers | W7-4 | 22-29 | .431 | Camden Yards · Baltimore, MD |
| 52 | Sun May 24 | vs Tigers | W5-3 | 23-29 | .442 | Camden Yards · Baltimore, MD |
| 53 | Sun May 24 | vs Tigers | L1-4 | 23-30 | .434 | Camden Yards · Baltimore, MD |
| 54 | Mon May 25 | vs Rays | W9-7 (13) | 24-30 | .444 | Camden Yards · Baltimore, MD |
| 55 | Tue May 26 | vs Rays | W6-1 | 25-30 | .455 | Camden Yards · Baltimore, MD |
| 56 | Wed May 27 | vs Rays | W11-2 | 26-30 | .464 | Camden Yards · Baltimore, MD |
| 57 | Thu May 28 | vs Blue Jays | L1-2 | 26-31 | .456 | Camden Yards · Baltimore, MD |
| 58 | Fri May 29 | vs Blue Jays | L5-6 | 26-32 | .448 | Camden Yards · Baltimore, MD |
| 59 | Sat May 30 | vs Blue Jays | W6-5 | 27-32 | .458 | Camden Yards · Baltimore, MD |
| 60 | Sun May 31 | vs Blue Jays | W9-5 | 28-32 | .467 | Camden Yards · Baltimore, MD |
| 61 | Tue Jun 2 | at Red Sox | W4-2 | 29-32 | .475 | Fenway Park · Boston, MA |
| 62 | Wed Jun 3 | at Red Sox | L1-8 | 29-33 | .468 | Fenway Park · Boston, MA |
| 63 | Thu Jun 4 | at Red Sox | W8-2 | 30-33 | .476 | Fenway Park · Boston, MA |
| 64 | Fri Jun 5 | at Blue Jays | W13-3 | 31-33 | .484 | Rogers Centre · Toronto, ON |
| 65 | Sat Jun 6 | at Blue Jays | L4-6 | 31-34 | .477 | Rogers Centre · Toronto, ON |
| 66 | Sun Jun 7 | at Blue Jays | L4-6 | 31-35 | .470 | Rogers Centre · Toronto, ON |
| 67 | Mon Jun 8 | vs Mariners | L3-6 | 31-36 | .463 | Camden Yards · Baltimore, MD |
| 68 | Tue Jun 9 | vs Mariners | L5-6 (10) | 31-37 | .456 | Camden Yards · Baltimore, MD |
| 69 | Wed Jun 10 | vs Mariners | W7-2 | 32-37 | .464 | Camden Yards · Baltimore, MD |
| 70 | Thu Jun 11 | vs Mariners | W7-5 | 33-37 | .471 | Camden Yards · Baltimore, MD |
| 71 | Fri Jun 12 | vs Padres | W7-3 | 34-37 | .479 | Camden Yards · Baltimore, MD |
| 72 | Sat Jun 13 | vs Padres | L3-9 | 34-38 | .472 | Camden Yards · Baltimore, MD |
| 73 | Sun Jun 14 | vs Padres | L2-5 | 34-39 | .466 | Camden Yards · Baltimore, MD |
| 74 | Tue Jun 16 | at Mariners | L1-3 | 34-40 | .459 | T-Mobile Park · Seattle, WA |
| 75 | Wed Jun 17 | at Mariners | W5-3 | 35-40 | .467 | T-Mobile Park · Seattle, WA |
| 76 | Thu Jun 18 | at Mariners | L0-3 | 35-41 | .461 | T-Mobile Park · Seattle, WA |
| 77 | Fri Jun 19 | at Dodgers | L5-6 | 35-42 | .455 | Dodger Stadium · Los Angeles, CA |
| 78 | Sat Jun 20 | at Dodgers | W3-2 | 36-42 | .462 | Dodger Stadium · Los Angeles, CA |
| 79 | Sun Jun 21 | at Dodgers | W12-1 | 37-42 | .468 | Dodger Stadium · Los Angeles, CA |
| 80 | Mon Jun 22 | at Angels | W6-1 | 38-42 | .475 | Angel Stadium · Anaheim, CA |
| 81 | Tue Jun 23 | at Angels | L1-5 | 38-43 | .469 | Angel Stadium · Anaheim, CA |
| 82 | Wed Jun 24 | at Angels | L6-7 (10) | 38-44 | .463 | Angel Stadium · Anaheim, CA |
| 83 | Fri Jun 26 | vs Nationals | W3-1 | 39-44 | .470 | Camden Yards · Baltimore, MD |
| 84 | Sat Jun 27 | vs Nationals | L3-4 (10) | 39-45 | .464 | Camden Yards · Baltimore, MD |
| 85 | Sun Jun 28 | vs Nationals | L4-6 | 39-46 | .459 | Camden Yards · Baltimore, MD |
| 86 | Mon Jun 29 | vs White Sox | L2-8 | 39-47 | .453 | Camden Yards · Baltimore, MD |
| 87 | Tue Jun 30 | vs White Sox | L3-9 | 39-48 | .448 | Camden Yards · Baltimore, MD |
| 88 | Wed Jul 1 | vs White Sox | W6-1 | 40-48 | .455 | Camden Yards · Baltimore, MD |
| 89 | Fri Jul 3 | at Reds | W3-0 | 41-48 | .461 | Great American Ball Park · Cincinnati, OH |
| 90 | Sat Jul 4 | at Reds | W8-5 | 42-48 | .467 | Great American Ball Park · Cincinnati, OH |
| 91 | Sun Jul 5 | at Reds | L2-3 | 42-49 | .462 | Great American Ball Park · Cincinnati, OH |
| 92 | Tue Jul 7 | vs Cubs | L2-5 | 42-50 | .457 | Camden Yards · Baltimore, MD |
| 93 | Wed Jul 8 | vs Cubs | L7-9 | 42-51 | .452 | Camden Yards · Baltimore, MD |
| 94 | Thu Jul 9 | vs Cubs | W3-2 | 43-51 | .457 | Camden Yards · Baltimore, MD |
| 95 | Fri Jul 10 | vs Royals | W5-3 | 44-51 | .463 | Camden Yards · Baltimore, MD |
| 96 | Sat Jul 11 | vs Royals | W6-1 | 45-51 | .469 | Camden Yards · Baltimore, MD |
| 97 | Sun Jul 12 | vs Royals | W8-2 | 46-51 | .474 | Camden Yards · Baltimore, MD |