| 1 | Sat Feb 21 | at San Jose | L0-3 | 0-0-1 | 0 PTS | PayPal Park · San Jose, CA |
| 2 | Sat Feb 28 | vsColumbus | D2-2 | 0-1-1 | 1 PTS | Children's Mercy Park · Kansas City, KS |
| 3 | Sat Mar 7 | vsSan Diego | L0-1 | 0-1-2 | 1 PTS | Children's Mercy Park · Kansas City, KS |
| 4 | Sat Mar 14 | atLA Galaxy | W2-1 | 1-1-2 | 4 PTS | Dignity Health Sports Park · Carson, CA |
| 5 | Sat Mar 21 | vsColorado | L1-4 | 1-1-3 | 4 PTS | Children's Mercy Park · Kansas City, KS |
| 6 | Sat Apr 4 | atSalt Lake | L1-3 | 1-1-4 | 4 PTS | America First Field · Sandy, UT |
| 7 | Sat Apr 11 | vsSan Jose | L1-3 | 1-1-5 | 4 PTS | Children's Mercy Park · Kansas City, KS |
| 8 | Fri Apr 17 | atVancouver | L0-3 | 1-1-6 | 4 PTS | BC Place · Vancouver, BC |
| 10 | Sat Apr 25 | atChicago | L0-5 | 1-1-7 | 4 PTS | Soldier Field · Chicago, IL |
| 11 | Sat May 2 | vsSeattle | D1-1 | 1-2-7 | 5 PTS | Children's Mercy Park · Kansas City, KS |
| 12 | Sat May 9 | atPortland | L0-6 | 1-2-8 | 5 PTS | Providence Park · Portland, OR |
| 13 | Wed May 13 | vsLA Galaxy | W3-1 | 2-2-8 | 8 PTS | Children's Mercy Park · Kansas City, KS |
| 14 | Sat May 16 | atAustin | W2-1 | 3-2-8 | 11 PTS | Q2 Stadium · Austin, TX |
| 15 | Sat May 23 | vsNew York | L1-2 | 3-2-9 | 11 PTS | Children's Mercy Park · Kansas City, KS |
| 16 | Thu Jul 16 | atSt. Louis | L2-3 | 3-2-10 | 11 PTS | Energizer Park · St. Louis, MO |
| 17 | Wed Jul 22 | vsMinnesota | W2-1 | 4-2-10 | 14 PTS | Children's Mercy Park · Kansas City, KS |
| 18 | Sat Jul 25 | atLAFC | L0-4 | 4-2-11 | 14 PTS | BMO Stadium · Los Angeles, CA |
| 19 | Sat Aug 1 | vsHouston | L0-2 | 4-2-12 | 14 PTS | Children's Mercy Park · Kansas City, KS |
| 20 | Sat Aug 15 | atColorado | L0-2 | 4-2-13 | 14 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 21 | Wed Aug 19 | vsSt. Louis | D1-1 | 4-3-13 | 15 PTS | Children's Mercy Park · Kansas City, KS |
| 22 | Sun Aug 23 | atAtlanta | L1-2 | 4-3-14 | 15 PTS | Mercedes-Benz Stadium · Atlanta, GA |
| 23 | Sat Aug 29 | vsVancouver | L0-3 | 4-3-15 | 15 PTS | Children's Mercy Park · Kansas City, KS |
| 24 | Sat Sep 5 | atDallas | L3-4 | 4-3-16 | 15 PTS | Toyota Stadium · Frisco, TX |
| 26 | Sat Sep 12 | vsLAFC | W3-1 | 5-3-16 | 18 PTS | Children's Mercy Park · Kansas City, KS |
| 27 | Sat Sep 19 | vsPhiladelphia | L3-4 | 5-3-16 | 18 PTS | Children's Mercy Park · Kansas City, KS |
| 28 | Sat Sep 26 | atHouston | W2-0 | 5-3-16 | 18 PTS | Shell Energy Stadium · Houston, TX |
| 25 | Thu Oct 1 | atSeattle | L1-2 | 4-3-16 | 15 PTS | Lumen Field · Seattle, WA |
| 29 | Sat Oct 10 | vsPortland | D3-3 | 5-3-16 | 18 PTS | Children's Mercy Park · Kansas City, KS |
| 30 | Wed Oct 14 | atNashville | L0-4 | 5-3-16 | 18 PTS | GEODIS Park · Nashville, TN |
