| 1 | Sat Feb 21 | vs Miami | W3-0 | 1-0-0 | 3 PTS | BMO Stadium · Los Angeles, CA |
| 2 | Sat Feb 28 | atHouston | W2-0 | 2-0-0 | 6 PTS | Shell Energy Stadium · Houston, TX |
| 3 | Sat Mar 7 | vsDallas | W1-0 | 3-0-0 | 9 PTS | BMO Stadium · Los Angeles, CA |
| 4 | Sat Mar 14 | vsSt. Louis | W2-0 | 4-0-0 | 12 PTS | BMO Stadium · Los Angeles, CA |
| 5 | Sat Mar 21 | atAustin | D0-0 | 4-1-0 | 13 PTS | Q2 Stadium · Austin, TX |
| 6 | Sat Apr 4 | vsOrlando | W6-0 | 5-1-0 | 16 PTS | BMO Stadium · Los Angeles, CA |
| 7 | Sat Apr 11 | atPortland | L1-2 | 5-1-1 | 16 PTS | Providence Park · Portland, OR |
| 8 | Sun Apr 19 | vsSan Jose | L1-4 | 5-1-2 | 16 PTS | BMO Stadium · Los Angeles, CA |
| 9 | Wed Apr 22 | vsColorado | D0-0 | 5-2-2 | 17 PTS | BMO Stadium · Los Angeles, CA |
| 10 | Sat Apr 25 | atMinnesota | W1-0 | 6-2-2 | 20 PTS | Allianz Field · Saint Paul, MN |
| 11 | Sat May 2 | atSan Diego | D2-2 | 6-3-2 | 21 PTS | Snapdragon Stadium · San Diego, CA |
| 12 | Sun May 10 | vsHouston | L1-4 | 6-3-3 | 21 PTS | BMO Stadium · Los Angeles, CA |
| 13 | Wed May 13 | atSt. Louis | L1-2 | 6-3-4 | 21 PTS | Energizer Park · St. Louis, MO |
| 14 | Sun May 17 | atNashville | L2-3 | 6-3-5 | 21 PTS | GEODIS Park · Nashville, TN |
| 15 | Sun May 24 | vsSeattle | W1-0 | 7-3-5 | 24 PTS | BMO Stadium · Los Angeles, CA |
| 16 | Fri Jul 17 | atLA Galaxy | W3-0 | 8-3-5 | 27 PTS | Dignity Health Sports Park · Carson, CA |
| 17 | Wed Jul 22 | vsSalt Lake | W3-1 | 9-3-5 | 30 PTS | BMO Stadium · Los Angeles, CA |
| 18 | Sat Jul 25 | vsKansas City | W4-0 | 10-3-5 | 33 PTS | BMO Stadium · Los Angeles, CA |
| 19 | Sat Aug 1 | atVancouver | D1-1 | 10-4-5 | 34 PTS | BC Place · Vancouver, BC |
| 20 | Sat Aug 15 | vsSan Diego | L0-1 | 10-4-6 | 34 PTS | BMO Stadium · Los Angeles, CA |
| 21 | Wed Aug 19 | atColorado | L0-1 | 10-4-7 | 34 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 22 | Sat Aug 22 | vsPortland | D1-1 | 10-5-7 | 35 PTS | BMO Stadium · Los Angeles, CA |
| 23 | Sat Aug 29 | atD.C. United | D0-0 | 10-6-7 | 36 PTS | Audi Field · Washington, D.C. |
| 24 | Sat Sep 5 | atSalt Lake | D2-2 | 10-7-7 | 37 PTS | America First Field · Sandy, UT |
| 25 | Wed Sep 9 | vsNew York | W2-0 | 11-7-7 | 40 PTS | BMO Stadium · Los Angeles, CA |
| 26 | Sat Sep 12 | atKansas City | L1-3 | 11-7-8 | 40 PTS | Children's Mercy Park · Kansas City, KS |
| 27 | Sat Sep 19 | atSan Jose | D2-2 | 11-7-8 | 40 PTS | Levi's® Stadium · Santa Clara, CA |
| 28 | Sat Sep 26 | atDallas | L0-1 | 11-7-8 | 40 PTS | Toyota Stadium · Frisco, TX |
| 29 | Sat Oct 10 | vsVancouver | D1-1 | 11-7-8 | 40 PTS | BMO Stadium · Los Angeles, CA |
