| 1 | Sun Feb 22 | at Seattle | L0-2 | 0-0-1 | 0 PTS | Lumen Field · Seattle, WA |
| 2 | Sat Feb 28 | vsPortland | W2-0 | 1-0-1 | 3 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 3 | Sat Mar 7 | vsLA Galaxy | W4-1 | 2-0-1 | 6 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 4 | Sat Mar 14 | atNYCFC | L1-3 | 2-0-2 | 6 PTS | Yankee Stadium · New York City, NY |
| 5 | Sat Mar 21 | atKansas City | W4-1 | 3-0-2 | 9 PTS | Children's Mercy Park · Kansas City, KS |
| 6 | Sat Apr 4 | atToronto | L2-3 | 3-0-3 | 9 PTS | BMO Field · Toronto, ON |
| 7 | Sat Apr 11 | vsHouston | W6-2 | 4-0-3 | 12 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 8 | Sat Apr 18 | vsMiami | L2-3 | 4-0-4 | 12 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 9 | Wed Apr 22 | atLAFC | D0-0 | 4-1-4 | 13 PTS | BMO Stadium · Los Angeles, CA |
| 10 | Sat Apr 25 | atVancouver | L1-3 | 4-1-5 | 13 PTS | BC Place · Vancouver, BC |
| 11 | Sat May 2 | atHouston | L0-1 | 4-1-6 | 13 PTS | Shell Energy Stadium · Houston, TX |
| 12 | Sat May 9 | vsSt. Louis | L0-1 | 4-1-7 | 13 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 13 | Wed May 13 | atMinnesota | W1-0 | 5-1-7 | 16 PTS | Allianz Field · Saint Paul, MN |
| 14 | Sat May 16 | atSalt Lake | L1-2 | 5-1-8 | 16 PTS | America First Field · Sandy, UT |
| 15 | Sat May 23 | vsDallas | L1-2 | 5-1-9 | 16 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 17 | Wed Jul 22 | vsSan Diego | W1-0 | 6-1-9 | 19 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 18 | Sat Jul 25 | atSt. Louis | L0-1 | 6-1-10 | 19 PTS | Energizer Park · St. Louis, MO |
| 19 | Sat Aug 1 | vsAustin | W1-0 | 6-1-10 | 19 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 20 | Sat Aug 15 | vsKansas City | W2-0 | 6-1-10 | 19 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 21 | Wed Aug 19 | vsLAFC | W1-0 | 6-1-10 | 19 PTS | Dick's Sporting Goods Park · Commerce City, CO |
| 22 | Sat Aug 22 | atSan Diego | L0-3 | 6-1-10 | 19 PTS | Snapdragon Stadium · San Diego, CA |
| 23 | Sat Aug 29 | vsSalt Lake | W1-0 | 6-1-10 | 19 PTS | Dick's Sporting Goods Park · Commerce City, CO |
