| 1 | Sat Aug 31 | at Ball State | W34-24 | 1-0 | 1.000 | Scheumann Stadium · Muncie, IN |
| 2 | Sat Sep 7 | vsE Illinois | W52-0 | 2-0 | 1.000 | Memorial Stadium · Bloomington, IN |
| 3 | Sat Sep 14 | vs#6Ohio State | L10-51 | 2-1 | .667 | Memorial Stadium · Bloomington, IN |
| 4 | Sat Sep 21 | vsUConn | W38-3 | 3-1 | .750 | Memorial Stadium · Bloomington, IN |
| 5 | Sat Sep 28 | at#25Michigan St | L31-40 | 3-2 | .600 | Spartan Stadium · East Lansing, MI |
| 6 | Sat Oct 12 | vsRutgers | W35-0 | 4-2 | .667 | Memorial Stadium · Bloomington, IN |
| 7 | Sat Oct 19 | atMaryland | W34-28 | 5-2 | .714 | SECU Stadium · College Park, MD |
| 8 | Sat Oct 26 | atNebraska | W38-31 | 6-2 | .750 | Memorial Stadium · Lincoln, NE |
| 9 | Sat Nov 2 | vsNorthwestern | W34-3 | 7-2 | .778 | Memorial Stadium · Bloomington, IN |
| 10 | Sat Nov 16 | at#9Penn State | L27-34 | 7-3 | .700 | Beaver Stadium · University Park, PA |
| 11 | Sat Nov 23 | vs#13Michigan | L14-39 | 7-4 | .636 | Memorial Stadium · Bloomington, IN |
| 12 | Sat Nov 30 | atPurdue | W44-41 (2OT) | 8-4 | .667 | Ross-Ade Stadium · West Lafayette, IN |
| BOWLS | Thu Jan 2 | atTennessee | L22-23 | 8-5 | .615 | Neyland Stadium · Knoxville, TN |
