| 1 | Mon Nov 6 | at Oklahoma | L59-89 | 0-1 | .000 | - | | Lloyd Noble Center · Norman, OK |
| 2 | Sat Nov 11 | vsUL Monroe | L64-74 | 0-2 | .000 | - | | McGuirk Arena · Mount Pleasant, MI |
| 3 | Mon Nov 13 | atFlorida St | L67-94 | 0-3 | .000 | - | | Donald L. Tucker Center · Tallahassee, FL |
| 4 | Wed Nov 15 | atSouth Florida | W68-63 | 1-3 | .250 | - | | Yuengling Center · Tampa, FL |
| 5 | Mon Nov 20 | vsSiena | W70-56 | 2-3 | .400 | - | | McGuirk Arena · Mount Pleasant, MI |
| 6 | Tue Nov 21 | atStetson | L61-71 | 2-4 | .333 | - | | Edmunds Center · Deland, FL |
| 7 | Wed Nov 29 | atOhio State | L61-88 | 2-5 | .286 | - | BTN | Value City Arena · Columbus, OH |
| 8 | Wed Dec 6 | vsValparaiso | W71-67 | 3-5 | .375 | - | | McGuirk Arena · Mount Pleasant, MI |
| 9 | Sat Dec 9 | at10Creighton | L64-109 | 3-6 | .333 | - | FS2 | CHI Health Center Omaha · Omaha, NE |
| 10 | Tue Dec 19 | vsTBD | W90-66 | 4-6 | .400 | - | | McGuirk Arena · Mount Pleasant, MI |
| 11 | Thu Dec 21 | vsDetroit Mercy | W75-63 | 5-6 | .455 | - | | McGuirk Arena · Mount Pleasant, MI |
| 12 | Sat Dec 30 | atLoyola Chicago | L35-73 | 5-7 | .417 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 13 | Tue Jan 2 | vsBuffalo | L64-76 | 5-8 | .385 | - | | McGuirk Arena · Mount Pleasant, MI |
| 14 | Sat Jan 6 | atBall State | W71-65 | 6-8 | .429 | - | | Worthen Arena · Muncie, IN |
| 15 | Tue Jan 9 | atE Michigan | W80-64 | 7-8 | .467 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 16 | Sat Jan 13 | vsKent State | W77-62 | 8-8 | .500 | - | | McGuirk Arena · Mount Pleasant, MI |
| 17 | Tue Jan 16 | atOhio | L61-73 | 8-9 | .471 | - | | Convocation Center (OH) · Athens, OH |
| 18 | Fri Jan 19 | vsToledo | W65-62 | 9-9 | .500 | - | CBSSN | McGuirk Arena · Mount Pleasant, MI |
| 19 | Tue Jan 23 | vsMiami OH | W71-55 | 10-9 | .526 | - | | McGuirk Arena · Mount Pleasant, MI |
| 20 | Sat Jan 27 | atW Michigan | W62-55 | 11-9 | .550 | - | | University Arena (MI) · Kalamazoo, MI |
| 21 | Tue Jan 30 | vsN Illinois | W84-77 (2OT) | 12-9 | .571 | - | | McGuirk Arena · Mount Pleasant, MI |
| 22 | Sat Feb 3 | atBowling Green | W77-76 (2OT) | 13-9 | .591 | - | | Stroh Center · Bowling Green, OH |
| 23 | Tue Feb 6 | atAkron | L47-68 | 13-10 | .565 | - | | James A. Rhodes Arena · Akron, OH |
| 24 | Sat Feb 10 | atOld Dominion | W58-57 | 14-10 | .583 | - | | Chartway Arena · Norfolk, VA |
| 25 | Sat Feb 17 | vsW Michigan | W69-42 | 15-10 | .600 | - | | McGuirk Arena · Mount Pleasant, MI |
| 26 | Tue Feb 20 | vsBowling Green | W62-60 (OT) | 16-10 | .615 | - | | McGuirk Arena · Mount Pleasant, MI |
| 27 | Sat Feb 24 | atMiami OH | L60-88 | 16-11 | .593 | - | | Millett Hall · Oxford, OH |
| 28 | Tue Feb 27 | vsBall State | L71-79 | 16-12 | .571 | - | | McGuirk Arena · Mount Pleasant, MI |
| 29 | Sat Mar 2 | atKent State | L73-79 (OT) | 16-13 | .552 | - | | M.A.C. Center · Kent, OH |
| 30 | Tue Mar 5 | atN Illinois | W69-63 | 17-13 | .567 | - | | NIU Convocation Center · Dekalb, IL |
| 31 | Fri Mar 8 | vsE Michigan | W65-62 (OT) | 18-13 | .581 | - | | McGuirk Arena · Mount Pleasant, MI |
| 32 | Thu Mar 14 | vsBowling Green | L56-66 | 18-14 | .563 | - | | McGuirk Arena · Mount Pleasant, MI |
