| 1 | Wed Nov 6 | vs TBD | W79-50 | 1-0 | 1.000 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 2 | Sat Nov 9 | at UT Martin | W92-75 | 2-0 | 1.000 | - | | Kathleen and Tom Elam Center · Martin, TN |
| 3 | Thu Nov 14 | vs Winthrop | W61-58 | 3-0 | 1.000 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 4 | Tue Nov 19 | at Kansas | L63-75 | 3-1 | .750 | - | | Allen Fieldhouse · Lawrence, KS |
| 5 | Sat Nov 23 | vs Delaware St | W98-66 | 4-1 | .800 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 6 | Sun Nov 24 | vs Southern Utah | W70-58 | 5-1 | .833 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 7 | Tue Nov 26 | vs Appalachian St | W78-69 | 6-1 | .857 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 8 | Sat Nov 30 | at Little Rock | W67-63 | 7-1 | .875 | - | | Jack Stephens Center · Little Rock, AR |
| 9 | Wed Dec 4 | at The Citadel | W96-84 | 8-1 | .889 | - | | McAlister Field House · Charleston, SC |
| 10 | Sat Dec 7 | at N Dakota St | L68-78 | 8-2 | .800 | - | | Scheels Center · Fargo, ND |
| 11 | Sun Dec 15 | vsTBD | W97-41 | 9-2 | .818 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 12 | Wed Dec 18 | at LSU | W74-63 | 10-2 | .833 | - | SEC Network | Pete Maravich Assembly Center · Baton Rouge, LA |
| 13 | Sat Dec 21 | vs Cleveland St | W80-55 | 11-2 | .846 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 14 | Sun Dec 29 | vsTBD | W117-48 | 12-2 | .857 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 15 | Wed Jan 1 | vs Wofford | W49-48 | 13-2 | .867 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 16 | Sat Jan 4 | at Furman | L56-65 | 13-3 | .813 | - | | Timmons Arena · Greenville, SC |
| 17 | Wed Jan 8 | at UNC Greensboro | W64-57 | 14-3 | .824 | - | | Greensboro Coliseum · Greensboro, NC |
| 18 | Sat Jan 11 | vs VMI | W61-55 | 15-3 | .833 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 19 | Wed Jan 15 | vs Samford | W88-63 | 16-3 | .842 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 20 | Sat Jan 18 | at W Carolina | W85-66 | 17-3 | .850 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 21 | Sat Jan 25 | vs Chattanooga | W75-64 | 18-3 | .857 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 22 | Wed Jan 29 | vs Mercer | L55-71 | 18-4 | .818 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 23 | Sat Feb 1 | vsUNC Greensboro | W82-65 | 19-4 | .826 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 24 | Wed Feb 5 | atChattanooga | W80-64 | 20-4 | .833 | - | | McKenzie Arena · Chattanooga, TN |
| 25 | Sat Feb 8 | atMercer | W73-60 | 21-4 | .840 | - | | Hawkins Arena · Macon, GA |
| 26 | Wed Feb 12 | vsThe Citadel | W91-67 | 22-4 | .846 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 27 | Sat Feb 15 | atVMI | W72-67 | 23-4 | .852 | - | | Cameron Hall · Lexington, VA |
| 28 | Wed Feb 19 | vsFurman | W75-66 | 24-4 | .857 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 29 | Sat Feb 22 | atSamford | W80-74 | 25-4 | .862 | - | | Pete Hanna Center · Homewood, AL |
| 30 | Wed Feb 26 | atWofford | W60-54 | 26-4 | .867 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 31 | Sat Feb 29 | vsW Carolina | W68-67 | 27-4 | .871 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 32 | Sat Mar 7 | vsVMI | W70-57 | 28-4 | .875 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 33 | Sun Mar 8 | vsW Carolina | W97-75 | 29-4 | .879 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 34 | Mon Mar 9 | vsWofford | W72-58 | 30-4 | .882 | - | ESPN | Freedom Hall Civic Center · Johnson City, TN |
