| 1 | Mon Nov 6 | vs TBD | W73-56 | 1-0 | 1.000 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 2 | Thu Nov 9 | at Elon | L76-79 | 1-1 | .500 | - | | Schar Center · Elon, NC |
| 3 | Mon Nov 13 | at Butler | L47-81 | 1-2 | .333 | - | CBS | Hinkle Fieldhouse · Indianapolis, IN |
| 4 | Fri Nov 17 | vs Davidson | W70-68 | 2-2 | .500 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 5 | Wed Nov 22 | at Cleveland St | L70-72 | 2-3 | .400 | - | | Wolstein Center · Cleveland, OH |
| 6 | Fri Nov 24 | vs Alabama A&M | W82-71 | 3-3 | .500 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 7 | Wed Nov 29 | at Appalachian St | L61-72 | 3-4 | .429 | - | | Holmes Convocation Center · Boone, NC |
| 8 | Sun Dec 3 | at J'Ville St | W61-59 | 4-4 | .500 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 9 | Sun Dec 10 | vs Tennessee Tech | W73-72 | 5-4 | .556 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 10 | Fri Dec 15 | vsTBD | W105-43 | 6-4 | .600 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 11 | Wed Dec 20 | vs Kansas City | W70-57 | 7-4 | .636 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 12 | Fri Dec 22 | at Utah State | L65-80 | 7-5 | .583 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 13 | Fri Dec 29 | at E Carolina | W86-70 | 8-5 | .615 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 14 | Wed Jan 3 | vs Mercer | W80-69 | 9-5 | .643 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 15 | Sat Jan 6 | at UNC Greensboro | L54-70 | 9-6 | .600 | - | | Greensboro Coliseum · Greensboro, NC |
| 16 | Wed Jan 10 | vs W Carolina | L66-80 | 9-7 | .563 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 17 | Sat Jan 13 | at Furman | L73-82 | 9-8 | .529 | - | | Timmons Arena · Greenville, SC |
| 18 | Wed Jan 17 | at Wofford | L73-75 | 9-9 | .500 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 19 | Sun Jan 21 | vs Chattanooga | L74-81 | 9-10 | .474 | - | ESPN2 | Freedom Hall Civic Center · Johnson City, TN |
| 20 | Wed Jan 24 | at VMI | W74-73 | 10-10 | .500 | - | | Cameron Hall · Lexington, VA |
| 21 | Sat Jan 27 | vs Samford | L72-75 | 10-11 | .476 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 22 | Wed Jan 31 | atMercer | W54-49 | 11-11 | .500 | - | | Hawkins Arena · Macon, GA |
| 23 | Sat Feb 3 | vs The Citadel | W62-60 | 12-11 | .522 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 24 | Wed Feb 7 | vsWofford | W57-50 | 13-11 | .542 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 25 | Sat Feb 10 | vsFurman | L63-65 | 13-12 | .520 | - | CBS | Freedom Hall Civic Center · Johnson City, TN |
| 26 | Wed Feb 14 | atChattanooga | L71-84 | 13-13 | .500 | - | | McKenzie Arena · Chattanooga, TN |
| 27 | Sat Feb 17 | atW Carolina | L65-70 | 13-14 | .481 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 28 | Wed Feb 21 | vsVMI | W82-69 | 14-14 | .500 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 29 | Sat Feb 24 | atSamford | L71-87 | 14-15 | .483 | - | | Pete Hanna Center · Homewood, AL |
| 30 | Wed Feb 28 | atThe Citadel | W81-63 | 15-15 | .500 | - | | McAlister Field House · Charleston, SC |
| 31 | Sat Mar 2 | vsUNC Greensboro | W66-65 | 16-15 | .516 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 32 | Fri Mar 8 | vsVMI | W98-66 | 17-15 | .531 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 33 | Sat Mar 9 | atUNC Greensboro | W73-62 | 18-15 | .545 | - | | Greensboro Coliseum · Greensboro, NC |
| 34 | Sun Mar 10 | atChattanooga | W85-84 (OT) | 19-15 | .559 | - | ESPNU | McKenzie Arena · Chattanooga, TN |
| 35 | Mon Mar 11 | atSamford | L69-76 | 19-16 | .543 | - | ESPN2 | Pete Hanna Center · Homewood, AL |
