| 1 | Tue Nov 7 | at #8Creighton | L54-105 | 0-1 | .000 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 2 | Thu Nov 9 | atNebraska | L54-81 | 0-2 | .000 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 3 | Tue Nov 14 | atFlorida | L68-89 | 0-3 | .000 | - | | O'Connell Center · Gainesville, FL |
| 4 | Mon Nov 20 | vsOregon | L54-67 | 0-4 | .000 | - | | Al Lawson Center · Tallahassee, FL |
| 5 | Wed Nov 29 | vsTBD | L85-92 (2OT) | 0-5 | .000 | - | | Al Lawson Center · Tallahassee, FL |
| 6 | Wed Dec 6 | atPresbyterian | W65-60 | 1-5 | .167 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 7 | Sat Dec 9 | vsTBD | W108-78 | 2-5 | .286 | - | | Al Lawson Center · Tallahassee, FL |
| 8 | Sat Dec 16 | atIowa | L52-88 | 2-6 | .250 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 9 | Sun Dec 17 | atIowa State | L58-96 | 2-7 | .222 | - | | James H. Hilton Coliseum · Ames, IA |
| 10 | Thu Dec 21 | atUCF | L56-69 | 2-8 | .200 | - | | Addition Financial Arena · Orlando, FL |
| 11 | Sat Dec 30 | atSouth Carolina | L62-94 | 2-9 | .182 | - | | Colonial Life Arena · Columbia, SC |
| 12 | Sat Jan 6 | atBethune | L86-98 | 2-10 | .167 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 13 | Sat Jan 13 | vsSouthern | L65-74 | 2-11 | .154 | - | | Al Lawson Center · Tallahassee, FL |
| 14 | Mon Jan 15 | vsGrambling | L52-65 | 2-12 | .143 | - | | Al Lawson Center · Tallahassee, FL |
| 15 | Sat Jan 20 | atAR-Pine Bluff | L97-99 | 2-13 | .133 | - | | H. O. Clemmons Arena · Pine Bluff, AR |
| 16 | Mon Jan 22 | atMiss Valley St | W81-70 | 3-13 | .188 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 17 | Sat Jan 27 | vsAlcorn St | L67-76 | 3-14 | .176 | - | | Al Lawson Center · Tallahassee, FL |
| 18 | Mon Jan 29 | vsJackson St | W88-86 | 4-14 | .222 | - | | Al Lawson Center · Tallahassee, FL |
| 19 | Sat Feb 3 | atAlabama A&M | L61-73 | 4-15 | .211 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 20 | Mon Feb 5 | atAlabama St | L53-62 | 4-16 | .200 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 21 | Sat Feb 10 | vsTexas So | L75-78 (OT) | 4-17 | .190 | - | | Al Lawson Center · Tallahassee, FL |
| 22 | Mon Feb 12 | vsPrairie View | L58-61 | 4-18 | .182 | - | ESPNU | Al Lawson Center · Tallahassee, FL |
| 23 | Sat Feb 17 | atJackson St | L55-77 | 4-19 | .174 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 24 | Mon Feb 19 | atAlcorn St | L68-79 | 4-20 | .167 | - | | Davey L. Whitney Complex · Lorman, MS |
| 25 | Sat Feb 24 | vsAlabama St | W73-65 | 5-20 | .200 | - | | Al Lawson Center · Tallahassee, FL |
| 26 | Mon Feb 26 | vsAlabama A&M | W76-58 | 6-20 | .231 | - | | Al Lawson Center · Tallahassee, FL |
| 27 | Sat Mar 2 | atGrambling | L68-75 | 6-21 | .222 | - | | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 28 | Mon Mar 4 | atSouthern | L44-58 | 6-22 | .214 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 29 | Sat Mar 9 | vsBethune | L66-67 (OT) | 6-23 | .207 | - | | Al Lawson Center · Tallahassee, FL |
