| 1 | Tue Nov 5 | at CA Baptist | L70-93 | 0-1 | .000 | - | | CBU Events Center · Riverside, CA |
| 2 | Wed Nov 6 | at UCSB | L62-83 | 0-2 | .000 | - | | The Thunderdome · Santa Barbara, CA |
| 3 | Tue Nov 12 | at Tulane | L79-88 | 0-3 | .000 | - | | Devlin Fieldhouse · New Orleans, LA |
| 4 | Sat Nov 16 | at SMU | L63-80 | 0-4 | .000 | - | | Moody Coliseum · Dallas, TX |
| 5 | Mon Nov 18 | at Texas St | L58-73 | 0-5 | .000 | - | | Strahan Arena at the University Events Center · San Marcos, TX |
| 6 | Fri Nov 22 | vs TBD | W72-53 | 1-5 | .167 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 7 | Tue Nov 26 | at UNLV | L57-80 | 1-6 | .143 | - | | Thomas & Mack Center · Las Vegas, NV |
| 8 | Sun Dec 1 | at Air Force | L52-76 | 1-7 | .125 | - | | Clune Arena · Colorado Springs, CO |
| 9 | Tue Dec 3 | at Denver | L58-67 | 1-8 | .111 | - | | Hamilton Gymnasium · Denver, CO |
| 10 | Mon Dec 16 | vsTBD | W113-67 | 2-8 | .200 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 11 | Thu Dec 19 | at Portland | W73-63 | 3-8 | .273 | - | | Chiles Center · Portland, OR |
| 12 | Sat Dec 21 | at #11Memphis | L49-77 | 3-9 | .250 | - | | FedExForum · Memphis, TN |
| 13 | Mon Dec 30 | at #6Baylor | L57-83 | 3-10 | .231 | - | | Ferrell Center · Waco, TX |
| 14 | Sat Jan 4 | vs Alabama St | W70-67 | 4-10 | .286 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 15 | Mon Jan 6 | vs Alabama A&M | L57-66 | 4-11 | .267 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 16 | Sat Jan 11 | at Alcorn St | W76-65 | 5-11 | .313 | - | | Davey L. Whitney Complex · Lorman, MS |
| 17 | Mon Jan 13 | at Southern | L50-56 | 5-12 | .294 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 18 | Sat Jan 18 | vs Texas So | L66-77 | 5-13 | .278 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 19 | Mon Jan 20 | vs Prairie View | L60-74 | 5-14 | .263 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 20 | Sat Jan 25 | vs Grambling | W71-53 | 6-14 | .300 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 21 | Sat Feb 1 | at Miss Valley St | W85-65 | 7-14 | .333 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 22 | Mon Feb 3 | at AR-Pine Bluff | W49-45 | 8-14 | .364 | - | | H. O. Clemmons Arena · Pine Bluff, AR |
| 23 | Sat Feb 8 | vsAlcorn St | W86-57 | 9-14 | .391 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 24 | Mon Feb 10 | vsSouthern | W67-51 | 10-14 | .417 | - | ESPNU | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 25 | Sat Feb 15 | atTexas So | L74-77 | 10-15 | .400 | - | | H&PE Arena · Houston, TX |
| 26 | Mon Feb 17 | atPrairie View | L61-70 | 10-16 | .385 | - | ESPNU | William Nicks Building · Prairie View, TX |
| 27 | Sat Feb 22 | atGrambling | L61-63 | 10-17 | .370 | - | | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 28 | Sat Feb 29 | vsMiss Valley St | W87-70 | 11-17 | .393 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 29 | Mon Mar 2 | vsAR-Pine Bluff | W76-56 | 12-17 | .414 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 30 | Thu Mar 5 | atAlabama St | W71-59 | 13-17 | .433 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 31 | Sat Mar 7 | atAlabama A&M | W54-51 | 14-17 | .452 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 32 | Tue Mar 10 | vsAlcorn St | W69-52 | 15-17 | .469 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
