| 1 | Mon Nov 6 | at Memphis | L77-94 | 0-1 | .000 | - | | FedExForum · Memphis, TN |
| 2 | Wed Nov 8 | at San Diego | L61-87 | 0-2 | .000 | - | | Jenny Craig Pavilion · San Diego, CA |
| 3 | Fri Nov 10 | at CA Baptist | L66-80 | 0-3 | .000 | - | | CBU Events Center · Riverside, CA |
| 4 | Tue Nov 14 | at LMU | L66-88 | 0-4 | .000 | - | | Gersten Pavilion · Los Angeles, CA |
| 5 | Thu Nov 16 | at Tulsa | L52-72 | 0-5 | .000 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 6 | Sun Nov 19 | at Missouri | W73-72 | 1-5 | .167 | - | | Mizzou Arena · Columbia, MO |
| 7 | Sat Nov 25 | at Georgetown | L81-88 | 1-6 | .143 | - | FS2 | Capital One Arena · Washington, D.C. |
| 8 | Tue Nov 28 | at Arkansas St | W75-71 | 2-6 | .250 | - | | First National Bank Arena · Jonesboro, AR |
| 9 | Sat Dec 9 | at #3Houston | L55-89 | 2-7 | .222 | - | | Fertitta Center · Houston, TX |
| 10 | Sat Dec 16 | at Howard | W81-74 | 3-7 | .300 | - | ESPNU | Burr Gymnasium · Washington, D.C. |
| 11 | Sun Dec 17 | vs NC A&T | W68-60 | 4-7 | .364 | - | ESPNU | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 12 | Wed Dec 20 | at #15Gonzaga | L76-100 | 4-8 | .333 | - | | McCarthey Athletic Center · Spokane, WA |
| 13 | Fri Dec 29 | at Northwestern | L63-74 | 4-9 | .308 | - | | Welsh-Ryan Arena · Evanston, IL |
| 14 | Sat Jan 6 | vs Alcorn St | W88-80 | 5-9 | .357 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 15 | Thu Jan 11 | at Alabama St | W73-63 | 6-9 | .400 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 16 | Sat Jan 13 | at Alabama A&M | W75-67 | 7-9 | .438 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 17 | Sat Jan 20 | vs Prairie View | L62-71 | 7-10 | .412 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 18 | Mon Jan 22 | vs Texas So | W73-64 | 8-10 | .444 | - | ESPNU | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 19 | Sat Jan 27 | at Bethune | L71-82 | 8-11 | .421 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 20 | Mon Jan 29 | at FAMU | L86-88 | 8-12 | .400 | - | | Al Lawson Center · Tallahassee, FL |
| 21 | Sat Feb 3 | vs Grambling | L62-70 | 8-13 | .381 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 22 | Mon Feb 5 | vs Southern | L63-72 | 8-14 | .364 | - | ESPN2 | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 23 | Sat Feb 10 | at Miss Valley St | W77-69 | 9-14 | .391 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 24 | Mon Feb 12 | at AR-Pine Bluff | W76-63 | 10-14 | .417 | - | | H. O. Clemmons Arena · Pine Bluff, AR |
| 25 | Sat Feb 17 | vsFAMU | W77-55 | 11-14 | .440 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 26 | Mon Feb 19 | vsBethune | W61-60 | 12-14 | .462 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 27 | Sat Feb 24 | atAlcorn St | L73-87 (OT) | 12-15 | .444 | - | | Davey L. Whitney Complex · Lorman, MS |
| 28 | Sat Mar 2 | atTexas So | L70-80 | 12-16 | .429 | - | | H&PE Arena · Houston, TX |
| 29 | Mon Mar 4 | atPrairie View | W79-74 | 13-16 | .448 | - | | William Nicks Building · Prairie View, TX |
| 30 | Thu Mar 7 | vsAR-Pine Bluff | W89-84 | 14-16 | .467 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 31 | Sat Mar 9 | vsMiss Valley St | W68-67 | 15-16 | .484 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 32 | Thu Mar 14 | atTexas So | L62-73 | 15-17 | .469 | - | | H&PE Arena · Houston, TX |
