| 1 | Sat Nov 9 | vs Wright St | L81-88 | +2 | 0-1 | .000 | - | | Millett Hall · Oxford, OH |
| 2 | Wed Nov 13 | atPurdue FW | W84-80 | -2½ | 1-1 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 3 | Sat Nov 16 | vsAlabama A&M | W79-63 | -21½ | 2-1 | .667 | - | | Millett Hall · Oxford, OH |
| 4 | Wed Nov 20 | vsTBD | W80-45 | - | 3-1 | .750 | - | | Millett Hall · Oxford, OH |
| 5 | Mon Nov 25 | atDrake | W67-59 | +4½ | 4-1 | .800 | - | | The Knapp Center · Des Moines, IA |
| 6 | Tue Nov 26 | atSouth Alabama | L71-82 | -1½ | 4-2 | .667 | - | | Mitchell Center · Mobile, AL |
| 7 | Wed Nov 27 | vsWright St | L66-71 | -2½ | 4-3 | .571 | - | | Millett Hall · Oxford, OH |
| 8 | Tue Dec 3 | vsN Kentucky | L54-76 | -4 | 4-4 | .500 | - | | Millett Hall · Oxford, OH |
| 9 | Sat Dec 7 | atEvansville | L87-101 | +4 | 4-5 | .444 | - | | Ford Center · Evansville, IN |
| 10 | Sun Dec 15 | vsMiss Valley St | W79-67 | -25 | 5-5 | .500 | - | | Millett Hall · Oxford, OH |
| 11 | Wed Dec 18 | at3Louisville | L46-70 | +22½ | 5-6 | .455 | - | ACC Network | KFC Yum! Center · Louisville, KY |
| 12 | Sat Dec 21 | vsBradley | W71-55 | +2 | 6-6 | .500 | - | | Millett Hall · Oxford, OH |
| 13 | Mon Dec 30 | vsTBD | W119-52 | - | 7-6 | .538 | - | | Millett Hall · Oxford, OH |
| 14 | Sat Jan 4 | atC Michigan | L82-93 | +3½ | 7-7 | .500 | - | | McGuirk Arena · Mount Pleasant, MI |
| 15 | Tue Jan 7 | atBowling Green | L76-78 | +8 | 7-8 | .467 | - | | Stroh Center · Bowling Green, OH |
| 16 | Fri Jan 10 | vsBuffalo | L78-83 | +1½ | 7-9 | .438 | - | CBS Sports Network | Millett Hall · Oxford, OH |
| 17 | Tue Jan 14 | vsKent State | W77-74 | +4½ | 8-9 | .471 | - | | Millett Hall · Oxford, OH |
| 18 | Sat Jan 18 | atBall State | L62-71 | +8½ | 8-10 | .444 | - | | Worthen Arena · Muncie, IN |
| 19 | Tue Jan 21 | vsAkron | L60-81 | +5 | 8-11 | .421 | - | | Millett Hall · Oxford, OH |
| 20 | Sat Jan 25 | vsE Michigan | W73-68 | -4 | 9-11 | .450 | - | | Millett Hall · Oxford, OH |
| 21 | Tue Jan 28 | vsC Michigan | PPD | -1 | 0-0 | .000 | - | | Millett Hall · Oxford, OH |
| 22 | Sat Feb 1 | atN Illinois | L55-70 | +4 | 9-12 | .429 | - | CBS Sports Network | NIU Convocation Center · Dekalb, IL |
| 23 | Tue Feb 4 | vsW Michigan | L60-64 | -5 | 9-13 | .409 | - | | Millett Hall · Oxford, OH |
| 24 | Sat Feb 8 | atOhio | L46-77 | +5½ | 9-14 | .391 | - | | Convocation Center (OH) · Athens, OH |
| 25 | Tue Feb 11 | atToledo | L57-65 | +9 | 9-15 | .375 | - | | Savage Arena · Toledo, OH |
| 26 | Sat Feb 15 | vsN Illinois | W65-60 | +3½ | 10-15 | .400 | - | | Millett Hall · Oxford, OH |
| 27 | Sat Feb 22 | atAkron | L65-75 | +12½ | 10-16 | .385 | - | | James A. Rhodes Arena · Akron, OH |
| 28 | Tue Feb 25 | atKent State | L61-74 | +9½ | 10-17 | .370 | - | | M.A.C. Center · Kent, OH |
| 29 | Thu Feb 27 | vsC Michigan | W76-57 | +1½ | 11-17 | .393 | - | | Millett Hall · Oxford, OH |
| 30 | Sat Feb 29 | vsBowling Green | W73-55 | +2½ | 12-17 | .414 | - | | Millett Hall · Oxford, OH |
| 31 | Tue Mar 3 | atBuffalo | L69-75 | +9 | 12-18 | .400 | - | | Alumni Arena · Buffalo, NY |
| 32 | Fri Mar 6 | vsOhio | L65-67 | -1 | 12-19 | .387 | - | | Millett Hall · Oxford, OH |
| 33 | Mon Mar 9 | atBuffalo | W85-79 | +9 | 13-19 | .406 | - | | Alumni Arena · Buffalo, NY |
