| 1 | Tue Nov 9 | vs Belmont | W92-80 | 1-0 | 1.000 | - | | Convocation Center (OH) · Athens, OH |
| 2 | Sat Nov 13 | at Cleveland St | W67-56 | 2-0 | 1.000 | - | | Wolstein Center · Cleveland, OH |
| 3 | Mon Nov 15 | vs Robert Morris | W85-71 | 3-0 | 1.000 | - | | Convocation Center (OH) · Athens, OH |
| 4 | Fri Nov 19 | at Kentucky | L59-77 | 3-1 | .750 | - | SEC Network | Rupp Arena · Lexington, KY |
| 5 | Mon Nov 22 | vs Mount St Mary | W73-59 | 4-1 | .800 | - | | Convocation Center (OH) · Athens, OH |
| 6 | Fri Nov 26 | vs TBD | W88-68 | 5-1 | .833 | - | | Convocation Center (OH) · Athens, OH |
| 7 | Wed Dec 1 | at LSU | L51-66 | 5-2 | .714 | - | | Pete Maravich Assembly Center · Baton Rouge, LA |
| 8 | Sat Dec 4 | vs St Francis PA | W78-75 | 6-2 | .750 | - | | Convocation Center (OH) · Athens, OH |
| 9 | Sat Dec 11 | at Stetson | W55-45 | 7-2 | .778 | - | | Edmunds Center · Deland, FL |
| 10 | Wed Dec 15 | vs Marshall | W75-65 | 8-2 | .800 | - | | Convocation Center (OH) · Athens, OH |
| 11 | Tue Dec 21 | vs SC Upstate | W85-70 | 9-2 | .818 | - | | Convocation Center (OH) · Athens, OH |
| 12 | Tue Dec 28 | vs E Michigan | PPD | 25-10 | .714 | - | | Convocation Center (OH) · Athens, OH |
| 13 | Sat Jan 1 | at W Michigan | W59-47 | 10-2 | .833 | - | | University Arena (MI) · Kalamazoo, MI |
| 14 | Tue Jan 4 | at Akron | W69-63 | 11-2 | .846 | - | CBS | James A. Rhodes Arena · Akron, OH |
| 15 | Fri Jan 7 | vs Kent State | W80-72 | 12-2 | .857 | - | CBS | Convocation Center (OH) · Athens, OH |
| 16 | Tue Jan 11 | vs Bowling Green | W85-78 | 13-2 | .867 | - | | Convocation Center (OH) · Athens, OH |
| 17 | Sat Jan 15 | at C Michigan | PPD | 25-10 | .714 | - | | McGuirk Arena · Mount Pleasant, MI |
| 18 | Tue Jan 18 | at Miami OH | W86-63 | 14-2 | .875 | - | | Millett Hall · Oxford, OH |
| 19 | Fri Jan 21 | vs Toledo | L69-87 | 14-3 | .824 | - | CBS | Convocation Center (OH) · Athens, OH |
| 20 | Tue Jan 25 | vs N Illinois | W74-62 | 15-3 | .833 | - | | Convocation Center (OH) · Athens, OH |
| 21 | Fri Jan 28 | at Buffalo | W74-53 | 16-3 | .842 | - | ESPNU | Alumni Arena · Buffalo, NY |
| 22 | Tue Feb 1 | vs Ball State | W87-63 | 17-3 | .850 | - | | Convocation Center (OH) · Athens, OH |
| 23 | Thu Feb 3 | vsE Michigan | W81-68 | 18-3 | .857 | - | | Convocation Center (OH) · Athens, OH |
| 24 | Sat Feb 5 | vsW Michigan | W77-64 | 19-3 | .864 | - | | Convocation Center (OH) · Athens, OH |
| 25 | Tue Feb 8 | atToledo | L62-77 | 19-4 | .826 | - | | Savage Arena · Toledo, OH |
| 26 | Thu Feb 10 | atC Michigan | W81-72 | 20-4 | .833 | - | | McGuirk Arena · Mount Pleasant, MI |
| 27 | Sat Feb 12 | atE Michigan | W74-56 | 21-4 | .840 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 28 | Tue Feb 15 | vsMiami OH | W91-78 | 22-4 | .846 | - | | Convocation Center (OH) · Athens, OH |
| 29 | Fri Feb 18 | atKent State | L52-75 | 22-5 | .815 | - | CBS | M.A.C. Center · Kent, OH |
| 30 | Tue Feb 22 | vsC Michigan | W76-50 | 23-5 | .821 | - | | Convocation Center (OH) · Athens, OH |
| 31 | Fri Feb 25 | vsAkron | L83-91 | 23-6 | .793 | - | | Convocation Center (OH) · Athens, OH |
| 32 | Tue Mar 1 | atBowling Green | L77-80 | 23-7 | .767 | - | | Stroh Center · Bowling Green, OH |
| 33 | Fri Mar 4 | atN Illinois | L57-58 | 23-8 | .742 | - | | NIU Convocation Center · Dekalb, IL |
| 34 | Thu Mar 10 | vsBall State | W77-67 | 24-8 | .750 | - | | Convocation Center (OH) · Athens, OH |
| 35 | Fri Mar 11 | atKent State | L61-67 | 24-9 | .727 | - | CBS | M.A.C. Center · Kent, OH |
| 36 | Sat Mar 19 | at Rice | W65-64 | 25-9 | .735 | - | | Tudor Fieldhouse · Houston, TX |
| 37 | Mon Mar 21 | at Abilene Chrstn | L86-91 | 25-10 | .714 | - | | Moody Coliseum (Abilene) · Abilene, TX |
