| 1 | Tue Nov 7 | vs Stony Brook | W90-74 | 1-0 | 1.000 | - | FS1 | Carnesecca Arena · Queens, NY |
| 2 | Mon Nov 13 | vs Michigan | L73-89 | 1-1 | .500 | - | FS1 | Carnesecca Arena · Queens, NY |
| 3 | Thu Nov 16 | at North Texas | W53-52 | 2-1 | .667 | - | ESPNU | The Super Pit · Denton, TX |
| 4 | Fri Nov 17 | at Dayton | L81-88 | 2-2 | .500 | - | ESPN2 | UD Arena · Dayton, OH |
| 5 | Sun Nov 19 | at Utah | W91-82 | 3-2 | .600 | - | ESPN | Jon M. Huntsman Center · Salt Lake City, UT |
| 6 | Sat Nov 25 | vs Holy Cross | W91-45 | 4-2 | .667 | - | FS2 | Carnesecca Arena · Queens, NY |
| 7 | Fri Dec 1 | at West Virginia | W79-73 | 5-2 | .714 | - | ESPN2 | WVU Coliseum · Morgantown, WV |
| 8 | Wed Dec 6 | vs Sacred Heart | W85-50 | 6-2 | .750 | - | CBS | Carnesecca Arena · Queens, NY |
| 9 | Sun Dec 10 | at Boston College | L80-86 | 6-3 | .667 | - | ESPNU | Silvio O. Conte Forum · Chestnut Hill, MA |
| 10 | Sat Dec 16 | vs Fordham | W77-55 | 7-3 | .700 | - | FS1 | Carnesecca Arena · Queens, NY |
| 11 | Wed Dec 20 | vs Xavier | W81-66 | 8-3 | .727 | - | FS1 | Carnesecca Arena · Queens, NY |
| 12 | Sat Dec 23 | at #5UConn | L65-69 | 8-4 | .667 | - | FOX | Gampel Pavilion · Storrs, CT |
| 13 | Sat Dec 30 | vs Hofstra | W84-79 | 9-4 | .692 | - | FS1 | Carnesecca Arena · Queens, NY |
| 14 | Tue Jan 2 | vs Butler | W86-70 | 10-4 | .714 | - | FS1 | Carnesecca Arena · Queens, NY |
| 15 | Sat Jan 6 | at Villanova | W81-71 | 11-4 | .733 | - | FOX | Finneran Pavilion · Villanova, PA |
| 16 | Wed Jan 10 | vs Providence | W75-73 | 12-4 | .750 | - | FS1 | Carnesecca Arena · Queens, NY |
| 17 | Sat Jan 13 | at #22Creighton | L65-66 | 12-5 | .706 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 18 | Tue Jan 16 | at Seton Hall | L65-80 | 12-6 | .667 | - | FS1 | Prudential Center · Newark, NJ |
| 19 | Sat Jan 20 | vs #17Marquette | L72-73 | 12-7 | .632 | - | FOX | Carnesecca Arena · Queens, NY |
| 20 | Wed Jan 24 | vsVillanova | W70-50 | 13-7 | .650 | - | FS1 | Carnesecca Arena · Queens, NY |
| 21 | Wed Jan 31 | atXavier | L77-88 | 13-8 | .619 | - | FS1 | Cintas Center · Cincinnati, OH |
| 22 | Sat Feb 3 | vs#1UConn | L64-77 | 13-9 | .591 | - | FOX | Carnesecca Arena · Queens, NY |
| 23 | Tue Feb 6 | vs DePaul | W85-57 | 14-9 | .609 | - | FS1 | Carnesecca Arena · Queens, NY |
| 24 | Sat Feb 10 | at#7Marquette | L75-86 | 14-10 | .583 | - | FS1 | Fiserv Forum · Milwaukee, WI |
| 25 | Tue Feb 13 | atProvidence | L72-75 | 14-11 | .560 | - | CBS | Amica Mutual Pavilion · Providence, RI |
| 26 | Sun Feb 18 | vsSeton Hall | L62-68 | 14-12 | .538 | - | FS1 | Carnesecca Arena · Queens, NY |
| 27 | Wed Feb 21 | at Georgetown | W90-85 | 15-12 | .556 | - | FS1 | Capital One Arena · Washington, D.C. |
| 28 | Sun Feb 25 | vs#15Creighton | W80-66 | 16-12 | .571 | - | CBS | Carnesecca Arena · Queens, NY |
| 29 | Wed Feb 28 | atButler | W82-59 | 17-12 | .586 | - | CBS | Hinkle Fieldhouse · Indianapolis, IN |
| 30 | Tue Mar 5 | atDePaul | W104-77 | 18-12 | .600 | - | FS1 | Wintrust Arena · Chicago, IL |
| 31 | Sat Mar 9 | vsGeorgetown | W86-78 | 19-12 | .613 | - | FOX | Carnesecca Arena · Queens, NY |
| 32 | Thu Mar 14 | atSeton Hall | W91-72 | 20-12 | .625 | - | FS1 | Prudential Center · Newark, NJ |
| 33 | Fri Mar 15 | at#2UConn | L90-95 | 20-13 | .606 | - | FOX | Gampel Pavilion · Storrs, CT |
