| 1 | Mon Nov 3 | vs TBD | W125-49 | 1-0 | 1.000 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 2 | Fri Nov 7 | vsCA Baptist | L61-69 | 1-1 | .500 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 3 | Mon Nov 10 | vsTBD | W130-63 | 2-1 | .667 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 4 | Sat Nov 15 | vsWeber St | W79-70 | 3-1 | .750 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 5 | Wed Nov 19 | atUtah Valley | L72-79 | 3-2 | .600 | - | ESPN+ | UCCU Center · Orem, UT |
| 6 | Sat Nov 22 | vsNorthern Iowa | L69-70 (OT) | 3-3 | .500 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 7 | Tue Nov 25 | vsNew Mexico St | L45-57 | 3-4 | .429 | - | | Bren Events Center · Irvine, CA |
| 8 | Wed Nov 26 | vsS Dakota St | W64-52 | 4-4 | .500 | - | | Bren Events Center · Irvine, CA |
| 9 | Sun Nov 30 | atSan Jose St | W72-63 | 5-4 | .556 | - | | Provident Credit Union Event Center · San Jose, CA |
| 10 | Thu Dec 4 | vsUC Riverside | W73-60 | 6-4 | .600 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 11 | Sat Dec 6 | vsCSU Northridge | W85-71 | 7-4 | .636 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 12 | Fri Dec 19 | vsBelmont | L58-84 | 7-5 | .583 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 13 | Sun Dec 21 | atN Dakota St | W74-73 | 8-5 | .615 | - | YouTube | Don Haskins Center · El Paso, TX |
| 14 | Mon Dec 22 | atNorfolk St | W89-70 | 9-5 | .643 | - | | Don Haskins Center · El Paso, TX |
| 15 | Thu Jan 1 | atBakersfield | W81-77 | 10-5 | .667 | - | ESPN+ | Icardo Center · Bakersfield, CA |
| 16 | Sat Jan 3 | atFullerton | W86-64 | 11-5 | .688 | - | ESPN+ | Titan Gym · Fullerton, CA |
| 17 | Thu Jan 8 | vsLong Beach St | W74-64 | 12-5 | .706 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 18 | Sat Jan 10 | atHawai'i | L66-67 | 12-6 | .667 | - | ESPN+ | Stan Sheriff Center · Honolulu, HI |
| 19 | Sat Jan 17 | atUC Davis | L72-75 | 12-7 | .632 | - | ESPN+ | University Credit Union Center · Davis, CA |
| 20 | Thu Jan 22 | atUC Riverside | W80-66 | 13-7 | .650 | - | ESPN+ | SRC Arena · Riverside, CA |
| 21 | Sat Jan 24 | atUC San Diego | W61-59 | 14-7 | .667 | - | ESPN+ | University Credit Union Center · Davis, CA |
| 22 | Thu Jan 29 | vsHawai'i | W87-76 (OT) | 15-7 | .682 | - | ESPNU | Bren Events Center · Irvine, CA |
| 23 | Thu Feb 5 | vsBakersfield | W78-62 | 16-7 | .696 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 24 | Sat Feb 7 | atUCSB | L79-84 | 16-8 | .667 | - | ESPNU | The Thunderdome · Santa Barbara, CA |
| 25 | Thu Feb 12 | atCal Poly | L73-79 | 16-9 | .640 | - | ESPN+ | Robert A. Mott Athletics Center · San Luis Obispo, CA |
| 26 | Sat Feb 14 | vsFullerton | W86-65 | 17-9 | .654 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 27 | Thu Feb 19 | atLong Beach St | W69-58 | 18-9 | .667 | - | ESPN+ | Walter Pyramid · Long Beach, CA |
| 28 | Sat Feb 21 | vsUC San Diego | L69-71 | 18-10 | .643 | - | ESPN+ | Bren Events Center · Irvine, CA |
| 29 | Thu Feb 26 | atCSU Northridge | W68-67 | 19-10 | .655 | - | ESPN+ | Premier America Credit Union Arena · Northridge, CA |
| 30 | Sat Feb 28 | vsUCSB | W64-60 | 20-10 | .667 | - | ESPN2 | Bren Events Center · Irvine, CA |
