| 1 | Wed Dec 9 | at La Salle | PPD | 8-7 | .533 | - | | Tom Gola Arena · Philadelphia, PA |
| 2 | Fri Dec 11 | vsNortheastern | W94-79 | 1-0 | 1.000 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 3 | Sun Dec 13 | atNortheastern | L75-78 | 1-1 | .500 | - | | Matthews Arena · Boston, MA |
| 4 | Wed Dec 16 | atLa Salle | W85-66 | 2-1 | .667 | - | | Tom Gola Arena · Philadelphia, PA |
| 5 | Mon Dec 21 | vsBryant | L88-93 | 2-2 | .500 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 6 | Wed Dec 30 | vsGeorge Mason | L92-93 (2OT) | 2-3 | .400 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 7 | Sat Jan 2 | atSaint Louis | PPD | 8-7 | .533 | - | NBCSN | Chaifetz Arena · St. Louis, MO |
| 9 | Sat Jan 9 | vsLa Salle | W83-67 | 3-3 | .500 | - | NBCSN | William D. Mullins Memorial Center · Amherst, MA |
| 10 | Wed Jan 13 | vsRhode Island | W80-78 (OT) | 4-3 | .571 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 11 | Sun Jan 17 | atFordham | W65-46 | 5-3 | .625 | - | NBCSN | Rose Hill Gymnasium · Bronx, NY |
| 13 | Sun Jan 24 | vsDavidson | L60-69 | 5-4 | .556 | - | CBS | William D. Mullins Memorial Center · Amherst, MA |
| 15 | Wed Feb 3 | vsFordham | W60-54 | 6-4 | .600 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 16 | Sat Feb 6 | atRhode Island | W75-63 | 7-4 | .636 | - | ESPN2 | Ryan Center · Kingston, RI |
| 18 | Tue Feb 23 | atRichmond | L65-79 | 7-5 | .583 | - | | Robins Center · Richmond, VA |
| 19 | Sun Feb 28 | atSaint Louis | PPD | 8-7 | .533 | - | | Chaifetz Arena · St. Louis, MO |
| 20 | Mon Mar 1 | atSaint Louis | L57-78 | 7-6 | .538 | - | | Chaifetz Arena · St. Louis, MO |
| 21 | Thu Mar 4 | vsSaint Joseph's | W100-66 | 8-6 | .571 | - | NBCSN | William D. Mullins Memorial Center · Amherst, MA |
| 22 | Fri Mar 5 | atSaint Louis | L72-86 | 8-7 | .533 | - | NBCSN | Chaifetz Arena · St. Louis, MO |
