| 1 | Sat Aug 16 | vs Newcastle | D0-0 | 0-1-0 | 1 PTS | Villa Park · Birmingham, England |
| 2 | Sat Aug 23 | atBrentford | L0-1 | 0-1-1 | 1 PTS | Gtech Community Stadium · Brentford, England |
| 3 | Sun Aug 31 | vsC Palace | L0-3 | 0-1-2 | 1 PTS | Villa Park · Birmingham, England |
| 4 | Sat Sep 13 | atEverton | D0-0 | 0-2-2 | 2 PTS | Goodison Park · Liverpool, England |
| 5 | Sun Sep 21 | atSunderland | D1-1 | 0-3-2 | 3 PTS | Stadium of Light · Sunderland, England |
| 6 | Sun Sep 28 | vsFulham | W3-1 | 1-3-2 | 6 PTS | Villa Park · Birmingham, England |
| 7 | Sun Oct 5 | vsBurnley | W2-1 | 2-3-2 | 9 PTS | Villa Park · Birmingham, England |
| 8 | Sun Oct 19 | atSpurs | W2-1 | 3-3-2 | 12 PTS | Tottenham Hotspur Stadium · London, England |
| 9 | Sun Oct 26 | vsMan City | W1-0 | 4-3-2 | 15 PTS | Villa Park · Birmingham, England |
| 10 | Sat Nov 1 | atLiverpool | L0-2 | 4-3-3 | 15 PTS | Nutter Center · Dayton, OH |
| 11 | Sun Nov 9 | vsB'mouth | W4-0 | 5-3-3 | 18 PTS | Villa Park · Birmingham, England |
| 12 | Sun Nov 23 | atLeeds | W2-1 | 6-3-3 | 21 PTS | Elland Road · Leeds, England |
| 13 | Sun Nov 30 | vsWolves | W1-0 | 7-3-3 | 24 PTS | Villa Park · Birmingham, England |
| 14 | Wed Dec 3 | atBrighton | W4-3 | 8-3-3 | 27 PTS | American Express Stadium · Brighton, England |
| 15 | Sat Dec 6 | vsArsenal | W2-1 | 9-3-3 | 30 PTS | Villa Park · Birmingham, England |
| 16 | Sun Dec 14 | atWest Ham | W3-2 | 10-3-3 | 33 PTS | London Stadium · London, England |
| 17 | Sun Dec 21 | vsMan Utd | W2-1 | 11-3-3 | 36 PTS | Villa Park · Birmingham, England |
| 18 | Sat Dec 27 | atChelsea | W2-1 | 12-3-3 | 39 PTS | Stamford Bridge · London, England |
| 19 | Tue Dec 30 | atArsenal | L1-4 | 12-3-4 | 39 PTS | Emirates Stadium · London, England |
| 20 | Sat Jan 3 | vsNott'm Forest | W3-1 | 13-3-4 | 42 PTS | Villa Park · Birmingham, England |
| 21 | Wed Jan 7 | atC Palace | D0-0 | 13-4-4 | 43 PTS | Silvio O. Conte Forum · Chestnut Hill, MA |
| 22 | Sun Jan 18 | vsEverton | L0-1 | 13-4-5 | 43 PTS | Villa Park · Birmingham, England |
| 23 | Sun Jan 25 | atNewcastle | W2-0 | 14-4-5 | 46 PTS | St. James' Park · Newcastle, England |
| 24 | Sun Feb 1 | vsBrentford | L0-1 | 14-4-6 | 46 PTS | Villa Park · Birmingham, England |
| 25 | Sat Feb 7 | atB'mouth | D1-1 | 14-5-6 | 47 PTS | Vitality Stadium · Bournemouth, England |
| 26 | Wed Feb 11 | vsBrighton | W1-0 | 15-5-6 | 50 PTS | Villa Park · Birmingham, England |
| 27 | Sat Feb 21 | vsLeeds | D1-1 | 15-6-6 | 51 PTS | Villa Park · Birmingham, England |
| 28 | Fri Feb 27 | atWolves | L0-2 | 15-6-7 | 51 PTS | Molineux Stadium · Wolverhampton, England |
| 29 | Wed Mar 4 | vsChelsea | L1-4 | 15-6-8 | 51 PTS | Villa Park · Birmingham, England |
| 30 | Sun Mar 15 | atMan Utd | L1-3 | 15-6-9 | 51 PTS | Old Trafford · Manchester, England |
| 31 | Sun Mar 22 | vsWest Ham | W2-0 | 1-1-0 | 4 PTS | Villa Park · Birmingham, England |
| 32 | Sun Apr 12 | atNott'm Forest | D1-1 | 1-2-0 | 5 PTS | The City Ground · Nottingham, England |
