| 1 | Sat Aug 16 | at Brighton | D1-1 | 0-1-0 | 1 PTS | American Express Stadium · Brighton, England |
| 2 | Sun Aug 24 | vsMan Utd | D1-1 | 0-2-0 | 2 PTS | Craven Cottage · London, England |
| 3 | Sat Aug 30 | atChelsea | L0-2 | 0-2-1 | 2 PTS | Stamford Bridge · London, England |
| 4 | Sat Sep 13 | vsLeeds | W1-0 | 1-2-1 | 5 PTS | Craven Cottage · London, England |
| 5 | Sat Sep 20 | vsBrentford | W3-1 | 2-2-1 | 8 PTS | Craven Cottage · London, England |
| 6 | Sun Sep 28 | atA Villa | L1-3 | 2-2-2 | 8 PTS | Villa Park · Birmingham, England |
| 7 | Fri Oct 3 | atB'mouth | L1-3 | 2-2-3 | 8 PTS | Vitality Stadium · Bournemouth, England |
| 8 | Sat Oct 18 | vsArsenal | L0-1 | 2-2-4 | 8 PTS | Craven Cottage · London, England |
| 9 | Sat Oct 25 | atNewcastle | L1-2 | 2-2-5 | 8 PTS | St. James' Park · Newcastle, England |
| 10 | Sat Nov 1 | vsWolves | W3-0 | 3-2-5 | 11 PTS | Craven Cottage · London, England |
| 11 | Sat Nov 8 | atEverton | L0-2 | 3-2-6 | 11 PTS | Goodison Park · Liverpool, England |
| 12 | Sat Nov 22 | vsSunderland | W1-0 | 4-2-6 | 14 PTS | Craven Cottage · London, England |
| 13 | Sat Nov 29 | atSpurs | W2-1 | 5-2-6 | 17 PTS | Tottenham Hotspur Stadium · London, England |
| 14 | Tue Dec 2 | vsMan City | L4-5 | 5-2-7 | 17 PTS | Craven Cottage · London, England |
| 15 | Sun Dec 7 | vsC Palace | L1-2 | 5-2-8 | 17 PTS | Craven Cottage · London, England |
| 16 | Sat Dec 13 | atBurnley | W3-2 | 6-2-8 | 20 PTS | Turf Moor · Burnley, England |
| 17 | Mon Dec 22 | vsNott'm Forest | W1-0 | 7-2-8 | 23 PTS | Craven Cottage · London, England |
| 18 | Sat Dec 27 | atWest Ham | W1-0 | 8-2-8 | 26 PTS | London Stadium · London, England |
| 19 | Thu Jan 1 | atC Palace | D1-1 | 8-3-8 | 27 PTS | Silvio O. Conte Forum · Chestnut Hill, MA |
| 20 | Sun Jan 4 | vsLiverpool | D2-2 | 8-4-8 | 28 PTS | Craven Cottage · London, England |
| 21 | Wed Jan 7 | vsChelsea | W2-1 | 9-4-8 | 31 PTS | Craven Cottage · London, England |
| 22 | Sat Jan 17 | atLeeds | L0-1 | 9-4-9 | 31 PTS | Elland Road · Leeds, England |
| 23 | Sat Jan 24 | vsBrighton | W2-1 | 10-4-9 | 34 PTS | Craven Cottage · London, England |
| 24 | Sun Feb 1 | atMan Utd | L2-3 | 10-4-10 | 34 PTS | Old Trafford · Manchester, England |
| 25 | Sat Feb 7 | vsEverton | L1-2 | 10-4-11 | 34 PTS | Craven Cottage · London, England |
| 26 | Wed Feb 11 | atMan City | L0-3 | 10-4-12 | 34 PTS | Etihad Stadium · Manchester, England |
| 27 | Sun Feb 22 | atSunderland | W3-1 | 11-4-12 | 37 PTS | Stadium of Light · Sunderland, England |
| 28 | Sun Mar 1 | vsSpurs | W2-1 | 12-4-12 | 40 PTS | Craven Cottage · London, England |
| 29 | Wed Mar 4 | vsWest Ham | L0-1 | 12-4-13 | 40 PTS | Craven Cottage · London, England |
| 30 | Sun Mar 15 | atNott'm Forest | D0-0 | 12-5-13 | 41 PTS | The City Ground · Nottingham, England |
| 31 | Sat Mar 21 | vsBurnley | W3-1 | 1-1-0 | 4 PTS | Craven Cottage · London, England |
| 32 | Sat Apr 11 | atLiverpool | L0-2 | 1-1-1 | 4 PTS | Nutter Center · Dayton, OH |
