| 1 | Mon Aug 18 | at Leeds | L0-1 | 0-0-1 | 0 PTS | Elland Road · Leeds, England |
| 2 | Sun Aug 24 | vsBrighton | W2-0 | 1-0-1 | 3 PTS | Goodison Park · Liverpool, England |
| 3 | Sat Aug 30 | atWolves | W3-2 | 2-0-1 | 6 PTS | Molineux Stadium · Wolverhampton, England |
| 4 | Sat Sep 13 | vsA Villa | D0-0 | 2-1-1 | 7 PTS | Goodison Park · Liverpool, England |
| 5 | Sat Sep 20 | atLiverpool | L1-2 | 2-1-2 | 7 PTS | Anfield · Liverpool, England |
| 6 | Mon Sep 29 | vsWest Ham | D1-1 | 2-2-2 | 8 PTS | Goodison Park · Liverpool, England |
| 7 | Sun Oct 5 | vsC Palace | W2-1 | 3-2-2 | 11 PTS | Goodison Park · Liverpool, England |
| 8 | Sat Oct 18 | atMan City | L0-2 | 3-2-3 | 11 PTS | Etihad Stadium · Manchester, England |
| 9 | Sun Oct 26 | vsSpurs | L0-3 | 3-2-4 | 11 PTS | Goodison Park · Liverpool, England |
| 10 | Mon Nov 3 | atSunderland | D1-1 | 3-3-4 | 12 PTS | Stadium of Light · Sunderland, England |
| 11 | Sat Nov 8 | vsFulham | W2-0 | 4-3-4 | 15 PTS | Goodison Park · Liverpool, England |
| 12 | Mon Nov 24 | atMan Utd | W1-0 | 5-3-4 | 18 PTS | Old Trafford · Manchester, England |
| 13 | Sat Nov 29 | vsNewcastle | L1-4 | 5-3-5 | 18 PTS | Goodison Park · Liverpool, England |
| 14 | Tue Dec 2 | atB'mouth | W1-0 | 6-3-5 | 21 PTS | Vitality Stadium · Bournemouth, England |
| 15 | Sat Dec 6 | vsNott'm Forest | W3-0 | 7-3-5 | 24 PTS | Goodison Park · Liverpool, England |
| 16 | Sat Dec 13 | atChelsea | L0-2 | 7-3-6 | 24 PTS | Stamford Bridge · London, England |
| 17 | Sat Dec 20 | vsArsenal | L0-1 | 7-3-7 | 24 PTS | Goodison Park · Liverpool, England |
| 18 | Sat Dec 27 | atBurnley | D0-0 | 7-4-7 | 25 PTS | Turf Moor · Burnley, England |
| 19 | Tue Dec 30 | atNott'm Forest | W2-0 | 8-4-7 | 28 PTS | The City Ground · Nottingham, England |
| 20 | Sun Jan 4 | vsBrentford | L2-4 | 8-4-8 | 28 PTS | Goodison Park · Liverpool, England |
| 21 | Wed Jan 7 | vsWolves | D1-1 | 8-5-8 | 29 PTS | Goodison Park · Liverpool, England |
| 22 | Sun Jan 18 | atA Villa | W1-0 | 9-5-8 | 32 PTS | Villa Park · Birmingham, England |
| 23 | Mon Jan 26 | vsLeeds | D1-1 | 9-6-8 | 33 PTS | Goodison Park · Liverpool, England |
| 24 | Sat Jan 31 | atBrighton | D1-1 | 9-7-8 | 34 PTS | American Express Stadium · Brighton, England |
| 25 | Sat Feb 7 | atFulham | W2-1 | 10-7-8 | 37 PTS | Craven Cottage · London, England |
| 26 | Tue Feb 10 | vsB'mouth | L1-2 | 10-7-9 | 37 PTS | Goodison Park · Liverpool, England |
| 27 | Mon Feb 23 | vsMan Utd | L0-1 | 10-7-10 | 37 PTS | Goodison Park · Liverpool, England |
| 28 | Sat Feb 28 | atNewcastle | W3-2 | 11-7-10 | 40 PTS | St. James' Park · Newcastle, England |
