| 2 | Sat Aug 23 | vs Spurs | 7:30 AM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 3 | Sun Aug 31 | at Brighton | 9:00 AM | 0-1-0 | 1 PTS | Amex Stadium · Brighton, England |
| 4 | Sun Sep 14 | vs Man Utd | 11:30 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 5 | Sun Sep 21 | at Arsenal | 11:30 AM | 1-0-0 | 3 PTS | Emirates Stadium · London, England |
| 6 | Sat Sep 27 | vs Burnley | 10:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 7 | Sun Oct 5 | at Brentford | 11:30 AM | 0-0-1 | 0 PTS | Gtech Community Stadium · Brentford, England |
| 8 | Sat Oct 18 | vs Everton | 10:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 9 | Sun Oct 26 | at A Villa | 10:00 AM | 0-1-0 | 1 PTS | Villa Park · Birmingham, England |
| 10 | Sat Nov 1 | vs B'mouth | 11:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 11 | Sat Nov 8 | vs Liverpool | 10:00 AM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 12 | Sat Nov 22 | at Newcastle | 10:00 AM | 0-1-0 | 1 PTS | St. James' Park · Newcastle, England |
| 13 | Sat Nov 29 | vs Leeds | 10:00 AM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 14 | Wed Dec 3 | at Fulham | 3:00 PM | 0-1-0 | 1 PTS | Craven Cottage · London, England |
| 15 | Sat Dec 6 | vs Sunderland | 10:00 AM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 16 | Sat Dec 13 | at C Palace | 10:00 AM | 0-1-0 | 1 PTS | Selhurst Park · London, England |
| 17 | Sat Dec 20 | vs West Ham | 10:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 18 | Sat Dec 27 | at Nott'm Forest | 10:00 AM | 1-0-0 | 3 PTS | The City Ground · Nottingham, England |
| 19 | Tue Dec 30 | atSunderland | 3:00 PM | 1-0-0 | 3 PTS | Stadium of Light · Sunderland, England |
| 20 | Sat Jan 3 | vs Chelsea | 10:00 AM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
| 21 | Wed Jan 7 | vsBrighton | 3:00 PM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
| 22 | Sat Jan 17 | atMan Utd | 10:00 AM | 0-0-1 | 0 PTS | Old Trafford · Manchester, England |
| 23 | Sat Jan 24 | vs Wolves | 10:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 24 | Sat Jan 31 | atSpurs | 10:00 AM | 1-0-0 | 3 PTS | Tottenham Hotspur Stadium · London, England |
| 25 | Sat Feb 7 | atLiverpool | 10:00 AM | 1-0-0 | 3 PTS | Anfield · Liverpool, England |
| 26 | Wed Feb 11 | vsFulham | 3:00 PM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
| 27 | Sat Feb 21 | vsNewcastle | 10:00 AM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
| 28 | Sat Feb 28 | atLeeds | 10:00 AM | 1-0-0 | 3 PTS | Elland Road · Leeds, England |
| 29 | Wed Mar 4 | vsNott'm Forest | 3:00 PM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 30 | Sat Mar 14 | atWest Ham | 11:00 AM | 0-0-1 | 0 PTS | London Stadium · London, England |
| 31 | Sat Mar 21 | vsC Palace | 11:00 AM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
| 32 | Sat Apr 11 | atChelsea | 10:00 AM | 0-1-0 | 1 PTS | Stamford Bridge · London, England |
| 33 | Sat Apr 18 | vsArsenal | 10:00 AM | 1-0-0 | 3 PTS | Etihad Stadium · Manchester, England |
| 34 | Sat Apr 25 | atBurnley | 10:00 AM | 0-0-1 | 0 PTS | Turf Moor · Burnley, England |
| 35 | Sat May 2 | atEverton | 10:00 AM | 0-0-1 | 0 PTS | Goodison Park · Liverpool, England |
| 36 | Sat May 9 | vsBrentford | 10:00 AM | 0-0-1 | 0 PTS | Etihad Stadium · Manchester, England |
| 37 | Sun May 17 | atB'mouth | 10:00 AM | 0-0-1 | 0 PTS | Vitality Stadium · Bournemouth, England |
| 38 | Sun May 24 | vsA Villa | 11:00 AM | 0-1-0 | 1 PTS | Etihad Stadium · Manchester, England |
