| 1 | Sat Aug 16 | vs West Ham | W3-0 | 1-0-0 | 3 PTS | Stadium of Light · Sunderland, England |
| 2 | Sat Aug 23 | atBurnley | L0-2 | 1-0-1 | 3 PTS | Turf Moor · Burnley, England |
| 3 | Sat Aug 30 | vsBrentford | W2-1 | 2-0-1 | 6 PTS | Stadium of Light · Sunderland, England |
| 4 | Sat Sep 13 | atC Palace | D0-0 | 2-1-1 | 7 PTS | Selhurst Park · London, England |
| 5 | Sun Sep 21 | vsA Villa | D1-1 | 2-2-1 | 8 PTS | Stadium of Light · Sunderland, England |
| 6 | Sat Sep 27 | atNott'm Forest | W1-0 | 3-2-1 | 11 PTS | The City Ground · Nottingham, England |
| 7 | Sat Oct 4 | atMan Utd | L0-2 | 3-2-2 | 11 PTS | Old Trafford · Manchester, England |
| 8 | Sat Oct 18 | vsWolves | W2-0 | 4-2-2 | 14 PTS | Stadium of Light · Sunderland, England |
| 9 | Sat Oct 25 | atChelsea | W2-1 | 5-2-2 | 17 PTS | Stamford Bridge · London, England |
| 10 | Mon Nov 3 | vsEverton | D1-1 | 5-3-2 | 18 PTS | Stadium of Light · Sunderland, England |
| 11 | Sat Nov 8 | vsArsenal | D2-2 | 5-4-2 | 19 PTS | Stadium of Light · Sunderland, England |
| 12 | Sat Nov 22 | atFulham | L0-1 | 5-4-3 | 19 PTS | Craven Cottage · London, England |
| 13 | Sat Nov 29 | vsB'mouth | W3-2 | 6-4-3 | 22 PTS | Stadium of Light · Sunderland, England |
| 14 | Wed Dec 3 | atLiverpool | D1-1 | 6-5-3 | 23 PTS | Anfield · Liverpool, England |
| 15 | Sat Dec 6 | atMan City | L0-3 | 6-5-4 | 23 PTS | Etihad Stadium · Manchester, England |
| 16 | Sun Dec 14 | vsNewcastle | W1-0 | 7-5-4 | 26 PTS | Stadium of Light · Sunderland, England |
| 17 | Sat Dec 20 | atBrighton | D0-0 | 7-6-4 | 27 PTS | American Express Stadium · Brighton, England |
| 18 | Sun Dec 28 | vsLeeds | D1-1 | 7-7-4 | 28 PTS | Stadium of Light · Sunderland, England |
| 19 | Thu Jan 1 | vsMan City | D0-0 | 7-8-4 | 29 PTS | Stadium of Light · Sunderland, England |
| 20 | Sun Jan 4 | atSpurs | D1-1 | 7-9-4 | 30 PTS | Tottenham Hotspur Stadium · London, England |
| 21 | Wed Jan 7 | atBrentford | L0-3 | 7-9-5 | 30 PTS | Gtech Community Stadium · Brentford, England |
| 22 | Sat Jan 17 | vsC Palace | W2-1 | 8-9-5 | 33 PTS | Stadium of Light · Sunderland, England |
| 23 | Sat Jan 24 | atWest Ham | L1-3 | 8-9-6 | 33 PTS | London Stadium · London, England |
| 24 | Mon Feb 2 | vsBurnley | W3-0 | 9-9-6 | 36 PTS | Stadium of Light · Sunderland, England |
| 25 | Sat Feb 7 | atArsenal | L0-3 | 9-9-7 | 36 PTS | Emirates Stadium · London, England |
| 26 | Wed Feb 11 | vsLiverpool | L0-1 | 9-9-8 | 36 PTS | Stadium of Light · Sunderland, England |
| 27 | Sun Feb 22 | vsFulham | L1-3 | 9-9-9 | 36 PTS | Stadium of Light · Sunderland, England |
| 28 | Sat Feb 28 | atB'mouth | D1-1 | 9-10-9 | 37 PTS | Vitality Stadium · Bournemouth, England |
