| 7 | Sat Oct 17 | at Brentford | 10:00 AM | 1-3-0 | 6 PTS | Gtech Community Stadium · Brentford, England |
| 8 | Sun Oct 25 | vsBrighton | 10:00 AM | 2-1-1 | 7 PTS | Anfield · Liverpool, England |
| 9 | Sun Nov 1 | vsArsenal | 11:30 AM | 4-0-0 | 12 PTS | Anfield · Liverpool, England |
| 10 | Sun Nov 8 | atC Palace | 9:00 AM | 1-0-3 | 3 PTS | Selhurst Park · London, England |
| 11 | Sun Nov 22 | vsMan Utd | 11:30 AM | 1-1-2 | 4 PTS | Anfield · Liverpool, England |
| 12 | Sun Nov 29 | atEverton | 7:00 AM | 1-3-0 | 6 PTS | Goodison Park · Liverpool, England |
| 13 | Wed Dec 2 | vsSunderland | 3:00 PM | 1-1-2 | 4 PTS | Anfield · Liverpool, England |
| 14 | Sat Dec 5 | atChelsea | 10:00 AM | 2-1-1 | 7 PTS | Stamford Bridge · London, England |
| 15 | Sat Dec 12 | vsLeeds | 10:00 AM | 2-2-0 | 8 PTS | Anfield · Liverpool, England |
| 16 | Sat Dec 19 | vsSpurs | 10:00 AM | 0-2-2 | 2 PTS | Anfield · Liverpool, England |
| 17 | Sat Dec 26 | atHull | 12:30 PM | 2-2-0 | 8 PTS | MKM Stadium · Hull, England |
| 18 | Wed Dec 30 | atA Villa | 3:15 PM | 0-1-3 | 1 PTS | Villa Park · Birmingham, England |
| 19 | Sat Jan 2 | vsCoventry | 10:00 AM | 0-0-4 | 0 PTS | Anfield · Liverpool, England |
| 20 | Tue Jan 5 | atSunderland | 3:15 PM | 1-1-2 | 4 PTS | Stadium of Light · Sunderland, England |
| 21 | Sat Jan 16 | vsC Palace | 10:00 AM | 1-0-3 | 3 PTS | Anfield · Liverpool, England |
| 22 | Sat Jan 23 | atMan Utd | 10:00 AM | 1-1-2 | 4 PTS | Old Trafford · Manchester, England |
| 23 | Sat Jan 30 | vsEverton | 10:00 AM | 1-3-0 | 6 PTS | Anfield · Liverpool, England |
| 24 | Sat Feb 6 | atArsenal | 10:00 AM | 4-0-0 | 12 PTS | Emirates Stadium · London, England |
| 25 | Wed Feb 10 | atCoventry | 3:00 PM | 0-0-4 | 0 PTS | Coventry Building Society Arena · Coventry, England |
| 26 | Sat Feb 20 | vsHull | 10:00 AM | 2-2-0 | 8 PTS | Anfield · Liverpool, England |
| 27 | Sat Feb 27 | atSpurs | 10:00 AM | 0-2-2 | 2 PTS | Tottenham Hotspur Stadium · London, England |
| 28 | Wed Mar 3 | vsA Villa | 3:00 PM | 0-1-3 | 1 PTS | Anfield · Liverpool, England |
| 29 | Sat Mar 13 | vsIpswich | 10:00 AM | 2-0-2 | 6 PTS | Anfield · Liverpool, England |
| 30 | Sat Mar 20 | atFulham | 11:00 AM | 0-1-3 | 1 PTS | Craven Cottage · London, England |
| 31 | Sat Apr 10 | vsNewcastle | 10:00 AM | 1-2-1 | 5 PTS | Anfield · Liverpool, England |
| 32 | Sat Apr 17 | atNott'm Forest | 10:00 AM | 1-2-1 | 5 PTS | The City Ground · Nottingham, England |
| 33 | Sat Apr 24 | atLeeds | 10:00 AM | 2-2-0 | 8 PTS | Elland Road · Leeds, England |
| 34 | Sat May 1 | vsChelsea | 10:00 AM | 2-1-1 | 7 PTS | Anfield · Liverpool, England |
| 35 | Sat May 8 | atMan City | 10:00 AM | 4-0-0 | 12 PTS | Etihad Stadium · Manchester, England |
| 36 | Sat May 15 | vsBrentford | 10:00 AM | 1-3-0 | 6 PTS | Anfield · Liverpool, England |
| 37 | Sun May 23 | atBrighton | 10:00 AM | 2-1-1 | 7 PTS | American Express Stadium · Brighton, England |
| 38 | Sun May 30 | vsB'mouth | 11:00 AM | 0-3-1 | 3 PTS | Anfield · Liverpool, England |
