| 1 | Fri Aug 15 | vs B'mouth | W4-2 | 1-0-0 | 3 PTS | Anfield · Liverpool, England |
| 2 | Mon Aug 25 | atNewcastle | W3-2 | 2-0-0 | 6 PTS | St. James' Park · Newcastle, England |
| 3 | Sun Aug 31 | vsArsenal | W1-0 | 3-0-0 | 9 PTS | Anfield · Liverpool, England |
| 4 | Sun Sep 14 | atBurnley | W1-0 | 4-0-0 | 12 PTS | Turf Moor · Burnley, England |
| 5 | Sat Sep 20 | vsEverton | W2-1 | 5-0-0 | 15 PTS | Anfield · Liverpool, England |
| 6 | Sat Sep 27 | atC Palace | L1-2 | 5-0-1 | 15 PTS | Selhurst Park · London, England |
| 7 | Sat Oct 4 | atChelsea | L1-2 | 5-0-2 | 15 PTS | Stamford Bridge · London, England |
| 8 | Sun Oct 19 | vsMan Utd | L1-2 | 5-0-3 | 15 PTS | Anfield · Liverpool, England |
| 9 | Sat Oct 25 | atBrentford | L2-3 | 5-0-4 | 15 PTS | Gtech Community Stadium · Brentford, England |
| 10 | Sat Nov 1 | vsA Villa | W2-0 | 6-0-4 | 18 PTS | Anfield · Liverpool, England |
| 11 | Sun Nov 9 | atMan City | L0-3 | 6-0-5 | 18 PTS | Etihad Stadium · Manchester, England |
| 12 | Sat Nov 22 | vsNott'm Forest | L0-3 | 6-0-6 | 18 PTS | Anfield · Liverpool, England |
| 13 | Sun Nov 30 | atWest Ham | W2-0 | 7-0-6 | 21 PTS | London Stadium · London, England |
| 14 | Wed Dec 3 | vsSunderland | D1-1 | 7-1-6 | 22 PTS | Anfield · Liverpool, England |
| 15 | Sat Dec 6 | atLeeds | D3-3 | 7-2-6 | 23 PTS | Elland Road · Leeds, England |
| 16 | Sat Dec 13 | vsBrighton | W2-0 | 8-2-6 | 26 PTS | Anfield · Liverpool, England |
| 17 | Sat Dec 20 | atSpurs | W2-1 | 9-2-6 | 29 PTS | Tottenham Hotspur Stadium · London, England |
| 18 | Sat Dec 27 | vsWolves | W2-1 | 10-2-6 | 32 PTS | Anfield · Liverpool, England |
| 19 | Thu Jan 1 | vsLeeds | D0-0 | 10-3-6 | 33 PTS | Anfield · Liverpool, England |
| 20 | Sun Jan 4 | atFulham | D2-2 | 10-4-6 | 34 PTS | Craven Cottage · London, England |
| 21 | Thu Jan 8 | atArsenal | D0-0 | 10-5-6 | 35 PTS | Emirates Stadium · London, England |
| 22 | Sat Jan 17 | vsBurnley | D1-1 | 10-6-6 | 36 PTS | Anfield · Liverpool, England |
| 23 | Sat Jan 24 | atB'mouth | L2-3 | 10-6-7 | 36 PTS | Vitality Stadium · Bournemouth, England |
| 24 | Sat Jan 31 | vsNewcastle | W4-1 | 11-6-7 | 39 PTS | Anfield · Liverpool, England |
| 25 | Sun Feb 8 | vsMan City | L1-2 | 11-6-8 | 39 PTS | Anfield · Liverpool, England |
| 26 | Wed Feb 11 | atSunderland | W1-0 | 12-6-8 | 42 PTS | Stadium of Light · Sunderland, England |
| 27 | Sun Feb 22 | atNott'm Forest | W1-0 | 13-6-8 | 45 PTS | The City Ground · Nottingham, England |
| 28 | Sat Feb 28 | vsWest Ham | W5-2 | 14-6-8 | 48 PTS | Anfield · Liverpool, England |
