| 1 | Sat Aug 17 | vs Southampton | W1-0 | 1-0-0 | 3 PTS | St. James' Park · Newcastle, England |
| 2 | Sun Aug 25 | at B'mouth | D1-1 | 1-1-0 | 4 PTS | Vitality Stadium · Bournemouth, England |
| 3 | Sun Sep 1 | vs Spurs | W2-1 | 2-1-0 | 7 PTS | St. James' Park · Newcastle, England |
| 4 | Sun Sep 15 | at Wolves | W2-1 | 3-1-0 | 10 PTS | Molineux Stadium · Wolverhampton, England |
| 5 | Sat Sep 21 | at Fulham | L1-3 | 3-1-1 | 10 PTS | Craven Cottage · London, England |
| 6 | Sat Sep 28 | vs Man City | D1-1 | 3-2-1 | 11 PTS | St. James' Park · Newcastle, England |
| 7 | Sat Oct 5 | at Everton | D0-0 | 3-3-1 | 12 PTS | Goodison Park · Liverpool, England |
| 8 | Sat Oct 19 | vs Brighton | L0-1 | 3-3-2 | 12 PTS | St. James' Park · Newcastle, England |
| 9 | Sun Oct 27 | at Chelsea | L1-2 | 3-3-3 | 12 PTS | Stamford Bridge · London, England |
| 10 | Sat Nov 2 | vs Arsenal | W1-0 | 4-3-3 | 15 PTS | St. James' Park · Newcastle, England |
| 11 | Sun Nov 10 | at Nott'm Forest | W3-1 | 5-3-3 | 18 PTS | The City Ground · Nottingham, England |
| 12 | Mon Nov 25 | vs West Ham | L0-2 | 5-3-4 | 18 PTS | St. James' Park · Newcastle, England |
| 13 | Sat Nov 30 | at C Palace | D1-1 | 5-4-4 | 19 PTS | Selhurst Park · London, England |
| 14 | Wed Dec 4 | vs Liverpool | D3-3 | 5-5-4 | 20 PTS | St. James' Park · Newcastle, England |
| 15 | Sat Dec 7 | at Brentford | L2-4 | 5-5-5 | 20 PTS | Gtech Community Stadium · Brentford, England |
| 16 | Sat Dec 14 | vs Leicester | W4-0 | 6-5-5 | 23 PTS | St. James' Park · Newcastle, England |
| 17 | Sat Dec 21 | at Ipswich | W4-0 | 7-5-5 | 26 PTS | Portman Road · Ipswich, England |
| 18 | Thu Dec 26 | vs A Villa | W3-0 | 8-5-5 | 29 PTS | St. James' Park · Newcastle, England |
| 19 | Mon Dec 30 | at Man Utd | W2-0 | 9-5-5 | 32 PTS | Old Trafford · Manchester, England |
| 20 | Sat Jan 4 | atSpurs | W2-1 | 10-5-5 | 35 PTS | Tottenham Hotspur Stadium · London, England |
| 21 | Wed Jan 15 | vsWolves | W3-0 | 11-5-5 | 38 PTS | St. James' Park · Newcastle, England |
| 22 | Sat Jan 18 | vsB'mouth | L1-4 | 11-5-6 | 38 PTS | St. James' Park · Newcastle, England |
| 23 | Sat Jan 25 | atSouthampton | W3-1 | 12-5-6 | 41 PTS | St. Mary's Stadium · Southampton, England |
| 24 | Sat Feb 1 | vsFulham | L1-2 | 12-5-7 | 41 PTS | St. James' Park · Newcastle, England |
| 25 | Sat Feb 15 | atMan City | L0-4 | 12-5-8 | 41 PTS | Etihad Stadium · Manchester, England |
