| 1 | Wed Nov 25 | at #23Ohio State | L67-94 | 0-1 | .000 | - | ESPN | Value City Arena · Columbus, OH |
| 2 | Sat Nov 28 | atUMass Lowell | W82-72 | 1-1 | .500 | - | | Costello Athletic Center · Lowell, MA |
| 3 | Wed Dec 2 | vsTBD | W177-108 | 2-1 | .667 | - | | Redbird Arena · Normal, IL |
| 4 | Sat Dec 5 | atMurray St | L65-76 | 2-2 | .500 | - | | CFSB Center · Murray, KY |
| 5 | Sat Dec 12 | atBall State | L66-82 | 2-3 | .400 | - | | Worthen Arena · Muncie, IN |
| 6 | Tue Dec 15 | vsChicago St | W91-62 | 3-3 | .500 | - | | Redbird Arena · Normal, IL |
| 7 | Sun Dec 27 | atLoyola Chicago | L60-90 | 3-4 | .429 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 8 | Mon Dec 28 | atLoyola Chicago | L55-86 | 3-5 | .375 | - | CBSSN | Joseph J. Gentile Arena · Chicago, IL |
| 9 | Sat Jan 2 | vsValparaiso | PPD | 7-18 | .280 | - | | Redbird Arena · Normal, IL |
| 10 | Sun Jan 3 | vsValparaiso | PPD | 7-18 | .280 | - | | Redbird Arena · Normal, IL |
| 11 | Sat Jan 9 | atEvansville | L48-57 | 3-6 | .333 | - | | Ford Center · Evansville, IN |
| 12 | Sun Jan 10 | atEvansville | W73-68 | 4-6 | .400 | - | | Ford Center · Evansville, IN |
| 13 | Sat Jan 16 | vsIndiana St | L65-73 | 4-7 | .364 | - | | Redbird Arena · Normal, IL |
| 14 | Sun Jan 17 | vsIndiana St | L68-74 | 4-8 | .333 | - | | Redbird Arena · Normal, IL |
| 15 | Wed Jan 20 | vsBradley | W71-56 | 5-8 | .385 | - | | Redbird Arena · Normal, IL |
| 16 | Sat Jan 23 | vsValparaiso | L60-69 | 5-9 | .357 | - | | Redbird Arena · Normal, IL |
| 17 | Sun Jan 24 | vsValparaiso | L66-70 | 5-10 | .333 | - | | Redbird Arena · Normal, IL |
| 18 | Sun Jan 31 | atDrake | L76-78 (OT) | 5-11 | .313 | - | | The Knapp Center · Des Moines, IA |
| 19 | Mon Feb 1 | at#25Drake | L60-95 | 5-12 | .294 | - | | The Knapp Center · Des Moines, IA |
| 20 | Sat Feb 6 | vsMissouri St | L67-74 | 5-13 | .278 | - | | Redbird Arena · Normal, IL |
| 21 | Sun Feb 7 | vsMissouri St | L62-72 | 5-14 | .263 | - | | Redbird Arena · Normal, IL |
| 22 | Sat Feb 13 | atS Illinois | W80-55 | 6-14 | .300 | - | | Banterra Center · Carbondale, IL |
| 23 | Sun Feb 14 | atS Illinois | L49-59 | 6-15 | .286 | - | | Banterra Center · Carbondale, IL |
| 24 | Thu Feb 18 | atBradley | W88-71 | 7-15 | .318 | - | | Carver Arena · Peoria, IL |
| 25 | Fri Feb 26 | vsNorthern Iowa | L56-70 | 7-16 | .304 | - | ESPNU | Redbird Arena · Normal, IL |
| 26 | Sat Feb 27 | vsNorthern Iowa | L87-94 (2OT) | 7-17 | .292 | - | CBSSN | Redbird Arena · Normal, IL |
| 27 | Thu Mar 4 | atNorthern Iowa | L60-65 | 7-18 | .280 | - | | McLeod Center · Cedar Falls, IA |
