| 1 | Mon Nov 7 | vs W Illinois | L68-71 | 0-1 | .000 | - | | Redbird Arena · Normal, IL |
| 2 | Thu Nov 10 | at E Illinois | W54-49 | 1-1 | .500 | - | | Lantz Arena · Charleston, IL |
| 3 | Sat Nov 12 | at N'Western St | W69-67 | 2-1 | .667 | - | | Prather Coliseum · Natchitoches, LA |
| 4 | Thu Nov 17 | vsN'Western St | L67-70 | 2-2 | .500 | - | | Redbird Arena · Normal, IL |
| 5 | Mon Nov 21 | at LSU | L61-77 | 2-3 | .400 | - | | Pete Maravich Assembly Center · Baton Rouge, LA |
| 6 | Tue Nov 22 | at Western KY | L66-78 | 2-4 | .333 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 7 | Wed Nov 23 | at Rhode Island | L44-57 | 2-5 | .286 | - | | Ryan Center · Kingston, RI |
| 8 | Thu Dec 1 | at Murray St | L67-70 (OT) | 2-6 | .250 | - | | CFSB Center · Murray, KY |
| 9 | Sun Dec 4 | vs Belmont | W87-77 | 3-6 | .333 | - | | Redbird Arena · Normal, IL |
| 10 | Wed Dec 7 | vs E Michigan | W87-81 | 4-6 | .400 | - | | Redbird Arena · Normal, IL |
| 11 | Sat Dec 10 | vs SIUE | W77-71 | 5-6 | .455 | - | | Redbird Arena · Normal, IL |
| 12 | Sat Dec 17 | at Ball State | L69-83 | 5-7 | .417 | - | | Worthen Arena · Muncie, IN |
| 13 | Mon Dec 19 | vs Chicago St | W66-52 | 6-7 | .462 | - | | Redbird Arena · Normal, IL |
| 14 | Wed Dec 28 | at UIC | L51-55 | 6-8 | .429 | - | | Credit Union 1 Arena · Chicago, IL |
| 15 | Sat Dec 31 | vs Northern Iowa | L60-66 | 6-9 | .400 | - | | Redbird Arena · Normal, IL |
| 16 | Wed Jan 4 | vs Indiana St | L67-76 | 6-10 | .375 | - | | Redbird Arena · Normal, IL |
| 17 | Sat Jan 7 | at Evansville | W69-61 | 7-10 | .412 | - | | Ford Center · Evansville, IN |
| 18 | Wed Jan 11 | vs Missouri St | W76-66 (OT) | 8-10 | .444 | - | | Redbird Arena · Normal, IL |
| 19 | Sat Jan 14 | at S Illinois | L57-69 | 8-11 | .421 | - | | Banterra Center · Carbondale, IL |
| 20 | Wed Jan 18 | atNorthern Iowa | L63-65 | 8-12 | .400 | - | | McLeod Center · Cedar Falls, IA |
| 21 | Sat Jan 21 | vs Valparaiso | L51-71 | 8-13 | .381 | - | | Redbird Arena · Normal, IL |
| 22 | Wed Jan 25 | at Bradley | L75-79 (OT) | 8-14 | .364 | - | | Carver Arena · Peoria, IL |
| 23 | Sun Jan 29 | vsS Illinois | W72-66 | 9-14 | .391 | - | | Redbird Arena · Normal, IL |
| 24 | Wed Feb 1 | vsUIC | W68-62 (OT) | 10-14 | .417 | - | | Redbird Arena · Normal, IL |
| 25 | Sat Feb 4 | atBelmont | L75-90 | 10-15 | .400 | - | | Curb Event Center Arena · Nashville, TN |
| 26 | Wed Feb 8 | vsBradley | L61-79 | 10-16 | .385 | - | | Redbird Arena · Normal, IL |
| 27 | Sat Feb 11 | atValparaiso | L76-81 | 10-17 | .370 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 28 | Wed Feb 15 | vsMurray St | L75-76 | 10-18 | .357 | - | | Redbird Arena · Normal, IL |
| 29 | Sat Feb 18 | atIndiana St | L64-80 | 10-19 | .345 | - | | Hulman Center · Terre Haute, IN |
| 30 | Wed Feb 22 | at Drake | L51-82 | 10-20 | .333 | - | | The Knapp Center · Des Moines, IA |
| 31 | Sun Feb 26 | vsEvansville | W72-53 | 11-20 | .355 | - | | Redbird Arena · Normal, IL |
| 32 | Thu Mar 2 | atNorthern Iowa | L62-75 | 11-21 | .344 | - | | McLeod Center · Cedar Falls, IA |
