| 1 | Mon Nov 4 | vs TBD | W100-58 | 1-0 | 1.000 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 2 | Fri Nov 8 | atCornell | L86-88 | 1-1 | .500 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 3 | Tue Nov 12 | vsTBD | W108-52 | 2-1 | .667 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 4 | Fri Nov 15 | atNorth Alabama | W97-96 (OT) | 3-1 | .750 | - | ESPN+ | Flowers Hall · Florence, AL |
| 5 | Sun Nov 17 | vsTexas So | W97-82 | 4-1 | .800 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 6 | Tue Nov 19 | atMichigan St | L75-83 | 4-2 | .667 | - | Peacock | Breslin Center · East Lansing, MI |
| 7 | Tue Nov 26 | vsN Dakota St | W103-98 (OT) | 5-2 | .714 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 8 | Wed Nov 27 | vsUtah Valley | W84-76 | 6-2 | .750 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 9 | Fri Nov 29 | vsW Georgia | W86-65 | 7-2 | .778 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 10 | Thu Dec 5 | atSC State | W88-81 | 8-2 | .800 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 11 | Sun Dec 8 | vsAustin Peay | W72-47 | 9-2 | .818 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 12 | Wed Dec 18 | atArizona | L64-96 | 9-3 | .750 | - | ESPN+ | McKale Center · Tucson, AZ |
| 13 | Sat Dec 21 | atAlabama A&M | W97-90 | 10-3 | .769 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 14 | Wed Jan 1 | vsThe Citadel | W86-56 | 11-3 | .786 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 15 | Sat Jan 4 | atW Carolina | W88-69 | 12-3 | .800 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 16 | Thu Jan 9 | vsVMI | W81-68 | 13-3 | .813 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 17 | Sat Jan 11 | vsUNC Greensboro | W76-69 | 14-3 | .824 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 18 | Wed Jan 15 | atMercer | W75-74 | 15-3 | .833 | - | ESPN+ | Hawkins Arena · Macon, GA |
| 19 | Sat Jan 18 | vsETSU | L60-65 | 15-4 | .789 | - | CBSSN | Pete Hanna Center · Homewood, AL |
| 20 | Thu Jan 23 | atChattanooga | W73-69 | 16-4 | .800 | - | ESPNU | McKenzie Arena · Chattanooga, TN |
| 21 | Sat Jan 25 | vsWofford | W77-61 | 17-4 | .810 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 22 | Wed Jan 29 | atFurman | L70-72 | 17-5 | .773 | - | CBSSN | Bon Secours Wellness Arena · Greenville, SC |
| 23 | Sat Feb 1 | atThe Citadel | W83-58 | 18-5 | .783 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 24 | Wed Feb 5 | vsMercer | W100-79 | 19-5 | .792 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 25 | Sat Feb 8 | atETSU | L59-66 | 19-6 | .760 | - | ESPN+ | Freedom Hall Civic Center · Johnson City, TN |
| 26 | Wed Feb 12 | vsChattanooga | L68-82 | 19-7 | .731 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 27 | Sat Feb 15 | atWofford | W76-68 | 20-7 | .741 | - | ESPNU | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 28 | Wed Feb 19 | vsFurman | L72-80 | 20-8 | .714 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 29 | Sat Feb 22 | vsW Carolina | W93-72 | 21-8 | .724 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 30 | Thu Feb 27 | atVMI | W95-83 | 22-8 | .733 | - | ESPN+ | Cameron Hall · Lexington, VA |
| 31 | Sat Mar 1 | atUNC Greensboro | L100-108 | 22-9 | .710 | - | ESPNEWS | Greensboro Coliseum · Greensboro, NC |
| 32 | Sat Mar 8 | vsFurman | L78-95 | 22-10 | .688 | - | ESPN+ | Pete Hanna Center · Homewood, AL |
| 33 | Wed Mar 19 | atGeorge Mason | L69-86 | 22-11 | .667 | - | ESPN+ | EagleBank Arena · Fairfax, VA |
