| 1 | Wed Nov 25 | vs #22UCLA | W73-58 | 1-0 | 1.000 | - | CBS | Viejas Arena · San Diego, CA |
| 2 | Fri Nov 27 | vs UC Irvine | W77-58 | 2-0 | 1.000 | - | | Viejas Arena · San Diego, CA |
| 3 | Wed Dec 2 | vs TBD | W83-41 | 3-0 | 1.000 | - | | Viejas Arena · San Diego, CA |
| 4 | Thu Dec 3 | vs Colorado St | PPD | 23-5 | .821 | - | | Viejas Arena · San Diego, CA |
| 5 | Sat Dec 5 | vsColorado St | PPD | 23-5 | .821 | - | | Viejas Arena · San Diego, CA |
| 6 | Sun Dec 6 | vs Pepperdine | W65-60 | 4-0 | 1.000 | - | | Viejas Arena · San Diego, CA |
| 7 | Thu Dec 10 | at #23Arizona St | W80-68 | 5-0 | 1.000 | #24 | FS1 | Desert Financial Arena · Tempe, AZ |
| 8 | Fri Dec 18 | vs BYU | L62-72 | 5-1 | .833 | #18 | CBS | Viejas Arena · San Diego, CA |
| 9 | Tue Dec 22 | at Saint Mary's | W74-49 | 6-1 | .857 | - | CBS | University Credit Union Pavilion · Moraga, CA |
| 10 | Sat Jan 2 | vsColorado St | L67-70 | 6-2 | .750 | - | CBS | Viejas Arena · San Diego, CA |
| 11 | Mon Jan 4 | vsColorado St | W78-65 | 7-2 | .778 | - | FS1 | Viejas Arena · San Diego, CA |
| 12 | Thu Jan 7 | vs Nevada | W65-60 | 8-2 | .800 | - | CBS | Viejas Arena · San Diego, CA |
| 13 | Sat Jan 9 | vsNevada | W69-67 | 9-2 | .818 | - | CBS | Viejas Arena · San Diego, CA |
| 14 | Thu Jan 14 | at Utah State | L45-57 | 9-3 | .750 | - | CBS | Dee Glen Smith Spectrum · Logan, UT |
| 15 | Sat Jan 16 | atUtah State | L59-64 | 9-4 | .692 | - | CBS | Dee Glen Smith Spectrum · Logan, UT |
| 16 | Fri Jan 22 | at Air Force | W98-61 | 10-4 | .714 | - | FS1 | Clune Arena · Colorado Springs, CO |
| 17 | Sun Jan 24 | atAir Force | W91-59 | 11-4 | .733 | - | FS1 | Clune Arena · Colorado Springs, CO |
| 18 | Thu Jan 28 | vs Wyoming | W87-57 | 12-4 | .750 | - | FS1 | Viejas Arena · San Diego, CA |
| 19 | Sat Jan 30 | vsWyoming | W98-71 | 13-4 | .765 | - | CBS | Viejas Arena · San Diego, CA |
| 22 | Mon Feb 8 | vs San Jose St | W85-54 | 14-4 | .778 | - | FS1 | Viejas Arena · San Diego, CA |
| 23 | Wed Feb 10 | vsSan Jose St | W77-55 | 15-4 | .789 | - | CBS | Viejas Arena · San Diego, CA |
| 24 | Thu Feb 18 | at Fresno St | W67-53 | 16-4 | .800 | #25 | CBS | Save Mart Center · Fresno, CA |
| 25 | Sat Feb 20 | atFresno St | W75-57 | 17-4 | .810 | #25 | CBS | Save Mart Center · Fresno, CA |
| 26 | Thu Feb 25 | vs Boise St | W78-66 (OT) | 18-4 | .818 | #22 | FS1 | Viejas Arena · San Diego, CA |
| 27 | Sat Feb 27 | vsBoise St | W62-58 | 19-4 | .826 | #22 | CBS | Viejas Arena · San Diego, CA |
| 28 | Wed Mar 3 | at UNLV | W71-62 | 20-4 | .833 | #19 | | Thomas & Mack Center · Las Vegas, NV |
| 29 | Thu Mar 11 | vsWyoming | W69-66 | 21-4 | .840 | - | CBS | Viejas Arena · San Diego, CA |
| 30 | Fri Mar 12 | vsNevada | W77-70 | 22-4 | .846 | - | CBS | Viejas Arena · San Diego, CA |
| 31 | Sat Mar 13 | vsUtah State | W68-57 | 23-4 | .852 | - | CBS | Viejas Arena · San Diego, CA |
| 32 | Fri Mar 19 | vs #11Syracuse | L62-78 | 23-5 | .821 | #6 | CBS | Viejas Arena · San Diego, CA |
New Mexico