| 1 | Mon Nov 3 | vs TBD | 8:00 PM | 0-0 | .000 | - | ESPN+ | Banterra Center · Carbondale, IL |
| 2 | Fri Nov 7 | vsKansas City | TBD | 13-20 | .394 | - | ESPN+ | Banterra Center · Carbondale, IL |
| 3 | Wed Nov 12 | atNevada | TBD | 17-16 | .515 | - | | Lawlor Events Center · Reno, NV |
| 4 | Mon Nov 17 | atN Dakota St | 8:00 PM | 21-11 | .656 | - | | Scheels Center · Fargo, ND |
| 5 | Sun Nov 23 | atDelaware | TBD | 16-20 | .444 | - | | Bob Carpenter Center · Newark, DE |
| 6 | Mon Nov 24 | vsUAB | TBD | 24-13 | .649 | - | | Banterra Center · Carbondale, IL |
| 7 | Wed Nov 26 | atMemphis | TBD | 29-6 | .829 | - | ESPN+ | FedExForum · Memphis, TN |
| 8 | Sat Nov 29 | vsLittle Rock | TBD | 19-14 | .576 | - | ESPN+ | Banterra Center · Carbondale, IL |
| 9 | Wed Dec 3 | atHigh Point | 7:00 PM | 29-6 | .829 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 10 | Wed Dec 10 | vsUT Martin | 8:00 PM | 14-19 | .424 | - | | Banterra Center · Carbondale, IL |
| 11 | Sat Dec 13 | atRichmond | TBD | 10-22 | .313 | - | | Robins Center · Richmond, VA |
| 12 | Thu Dec 18 | vsIllinois St | TBD | 22-14 | .611 | - | | Banterra Center · Carbondale, IL |
| 13 | Sun Dec 21 | atBradley | TBD | 28-9 | .757 | - | | Carver Arena · Peoria, IL |
| 14 | Mon Dec 29 | atMurray St | TBD | 16-17 | .485 | - | | CFSB Center · Murray, KY |
| 15 | Thu Jan 1 | vsValparaiso | TBD | 15-19 | .441 | - | | Banterra Center · Carbondale, IL |
| 16 | Sun Jan 4 | atBelmont | TBD | 22-11 | .667 | - | | Curb Event Center Arena · Nashville, TN |
| 17 | Wed Jan 7 | atUIC | TBD | 17-14 | .548 | - | | Credit Union 1 Arena · Chicago, IL |
| 18 | Wed Jan 14 | vsDrake | TBD | 31-4 | .886 | - | | Banterra Center · Carbondale, IL |
| 19 | Sat Jan 17 | vsBelmont | TBD | 22-11 | .667 | - | | Banterra Center · Carbondale, IL |
| 20 | Wed Jan 21 | atValparaiso | TBD | 15-19 | .441 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 21 | Sun Jan 25 | atEvansville | TBD | 11-21 | .344 | - | | Ford Center · Evansville, IN |
| 22 | Wed Jan 28 | vsNorthern Iowa | TBD | 20-13 | .606 | - | | Banterra Center · Carbondale, IL |
| 23 | Sat Jan 31 | vsUIC | TBD | 17-14 | .548 | - | | Banterra Center · Carbondale, IL |
| 24 | Tue Feb 3 | atIllinois St | TBD | 22-14 | .611 | - | | Redbird Arena · Normal, IL |
| 25 | Fri Feb 6 | vsMurray St | TBD | 16-17 | .485 | - | | Banterra Center · Carbondale, IL |
| 26 | Mon Feb 9 | atIndiana St | TBD | 14-18 | .438 | - | | Hulman Center · Terre Haute, IN |
| 27 | Thu Feb 12 | vsEvansville | TBD | 11-21 | .344 | - | | Banterra Center · Carbondale, IL |
| 28 | Sun Feb 15 | vsBradley | TBD | 28-9 | .757 | - | | Banterra Center · Carbondale, IL |
| 29 | Wed Feb 18 | atDrake | TBD | 31-4 | .886 | - | | The Knapp Center · Des Moines, IA |
| 30 | Sat Feb 21 | atNorthern Iowa | TBD | 20-13 | .606 | - | | McLeod Center · Cedar Falls, IA |
| 31 | Wed Feb 25 | vsIndiana St | TBD | 14-18 | .438 | - | | Banterra Center · Carbondale, IL |
