| 1 | Mon Nov 3 | at Rhode Island | L62-93 | - | 0-1 | .000 | - | ESPN+ | Ryan Center · Kingston, RI |
| 2 | Fri Nov 7 | vsTBD | W106-77 | - | 1-1 | .500 | - | ESPN+ | Edmunds Center · Deland, FL |
| 3 | Mon Nov 10 | atMiami | L61-102 | - | 1-2 | .333 | - | ACC Network | Watsco Center · Coral Gables, FL |
| 4 | Sun Nov 16 | atW Carolina | L65-76 | - | 1-3 | .250 | - | ESPN+ | Ramsey Regional Activity Center · Cullowhee, NC |
| 5 | Wed Nov 19 | vsHoward | W64-60 | - | 2-3 | .400 | - | ESPN+ | Edmunds Center · Deland, FL |
| 6 | Sat Nov 22 | vsVMI | W99-80 | - | 3-3 | .500 | - | ESPN+ | Edmunds Center · Deland, FL |
| 7 | Tue Nov 25 | vsWright St | L62-79 | +9½ | 3-4 | .429 | - | ESPN+ | Edmunds Center · Deland, FL |
| 8 | Sat Nov 29 | vsSouthern Utah | L68-70 | +1½ | 3-5 | .375 | - | ESPN+ | UPMC Events Center · Moon Township, PA |
| 9 | Sun Nov 30 | atRobert Morris | L62-80 | +11½ | 3-6 | .333 | - | ESPN+ | UPMC Events Center · Moon Township, PA |
| 10 | Tue Dec 2 | atGrand Canyon | L45-67 | +24½ | 3-7 | .300 | - | | GCU Arena · Phoenix, AZ |
| 11 | Sat Dec 6 | atSouth Carolina | L51-82 | +22½ | 3-8 | .273 | - | | Colonial Life Arena · Columbia, SC |
| 12 | Mon Dec 15 | vsTBD | W95-76 | - | 4-8 | .333 | - | ESPN+ | Edmunds Center · Deland, FL |
| 13 | Mon Dec 22 | atOklahoma | L54-107 | +31½ | 4-9 | .308 | - | SEC Network | Lloyd Noble Center · Norman, OK |
| 14 | Thu Jan 1 | atNorth Alabama | W70-67 | +9½ | 5-9 | .357 | - | ESPN+ | Flowers Hall · Florence, AL |
| 15 | Sat Jan 3 | atC Arkansas | L73-93 | +11½ | 5-10 | .333 | - | ESPN+ | Farris Center · Conway, AR |
| 16 | Thu Jan 8 | vsLipscomb | W91-83 | +11½ | 6-10 | .375 | - | ESPN+ | Edmunds Center · Deland, FL |
| 17 | Sat Jan 10 | vsAustin Peay | L69-81 | +9½ | 6-11 | .353 | - | ESPN+ | Edmunds Center · Deland, FL |
| 18 | Thu Jan 15 | vsW Georgia | W95-86 | +1½ | 7-11 | .389 | - | ESPN+ | Edmunds Center · Deland, FL |
| 19 | Sat Jan 17 | vsQueens | L81-87 | +10½ | 7-12 | .368 | - | ESPN+ | Edmunds Center · Deland, FL |
| 20 | Thu Jan 22 | atLipscomb | L74-79 (OT) | +15½ | 7-13 | .350 | - | ESPN+ | Allen Arena · Nashville, TN |
| 21 | Fri Jan 23 | atAustin Peay | L65-73 | +16½ | 7-14 | .333 | - | ESPN+ | Winfield Dunn Center · Clarksville, TN |
| 22 | Thu Jan 29 | atNorth Florida | W84-77 | -1½ | 8-14 | .364 | - | ESPN+ | UNF Arena · Jacksonville, FL |
| 23 | Sat Jan 31 | vsNorth Alabama | L66-68 | -1½ | 8-15 | .348 | - | ESPN+ | Edmunds Center · Deland, FL |
| 24 | Thu Feb 5 | atBellarmine | L71-92 | +4½ | 8-16 | .333 | - | ESPN+ | Knights Hall · Louisville, KY |
| 25 | Sat Feb 7 | atE Kentucky | L88-100 | +9½ | 8-17 | .320 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 26 | Wed Feb 11 | vsJacksonville | W67-62 | +2½ | 9-17 | .346 | - | ESPN+ | Edmunds Center · Deland, FL |
| 27 | Sat Feb 14 | atFGCU | L76-78 | +11½ | 9-18 | .333 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 28 | Thu Feb 19 | vsC Arkansas | L76-88 | +9½ | 9-19 | .321 | - | ESPN+ | Edmunds Center · Deland, FL |
| 29 | Sat Feb 21 | vsNorth Florida | W76-71 | -1½ | 10-19 | .345 | - | ESPN+ | Edmunds Center · Deland, FL |
| 30 | Thu Feb 26 | atJacksonville | L85-89 | +7½ | 10-20 | .333 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 31 | Sat Feb 28 | vsFGCU | W78-63 | +5½ | 11-20 | .355 | - | ESPN+ | Edmunds Center · Deland, FL |
| 32 | Wed Mar 4 | atE Kentucky | W92-76 | +5½ | 12-20 | .375 | - | ESPN+ | UNF Arena · Jacksonville, FL |
| 33 | Fri Mar 6 | atAustin Peay | L60-69 | +11½ | 12-21 | .364 | - | ESPN+ | Winfield Dunn Center · Clarksville, TN |
