| 1 | Mon Nov 3 | vs TBD | 7:00 PM | 0-0 | .000 | - | ESPN+ | Costello Athletic Center · Lowell, MA |
| 2 | Fri Nov 7 | at#4UConn | 7:30 PM | 24-11 | .686 | - | Peacock | Gampel Pavilion · Storrs, CT |
| 3 | Mon Nov 10 | vsNew Haven | TBD | 0-0 | .000 | - | ESPN+ | Costello Athletic Center · Lowell, MA |
| 4 | Thu Nov 13 | atColumbia | 7:00 PM | 12-15 | .444 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 5 | Sun Nov 16 | atWake Forest | 2:00 PM | 21-11 | .656 | - | ACC Extra | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
| 6 | Wed Nov 19 | atBradley | TBD | 28-9 | .757 | - | ESPN+ | Carver Arena · Peoria, IL |
| 7 | Sat Nov 22 | atSaint Peter's | TBD | 12-16 | .429 | - | ESPN+ | Yanitelli Center · Jersey City, NJ |
| 8 | Wed Nov 26 | atStonehill | 12:00 PM | 15-17 | .469 | - | | placeholder · sf, ca |
| 9 | Sat Nov 29 | vsTBD | 1:00 PM | 0-0 | .000 | - | | Costello Athletic Center · Lowell, MA |
| 10 | Sat Dec 6 | atUMass | 4:00 PM | 12-20 | .375 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 11 | Wed Dec 10 | vsTBD | TBD | 0-0 | .000 | - | | Costello Athletic Center · Lowell, MA |
| 12 | Sat Dec 13 | atQuinnipiac | 2:00 PM | 20-13 | .606 | - | | M&T Bank Arena · Hamden, CT |
| 13 | Tue Dec 16 | vsSacred Heart | TBD | 15-18 | .455 | - | | Costello Athletic Center · Lowell, MA |
| 14 | Sun Dec 21 | atBoston Univ | TBD | 16-16 | .500 | - | | Case Gym · Boston, MA |
| 15 | Mon Dec 29 | atIowa | TBD | 17-16 | .515 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 16 | Sat Jan 3 | vsAlbany | TBD | 17-16 | .515 | - | | Costello Athletic Center · Lowell, MA |
| 17 | Thu Jan 8 | atBryant | TBD | 23-12 | .657 | - | | Chace Athletic Center · Smithfield, RI |
| 18 | Sat Jan 10 | atBinghamton | TBD | 15-17 | .469 | - | | Events Center (Binghamton) · Binghamton, NY |
| 19 | Thu Jan 15 | vsNJIT | TBD | 6-25 | .194 | - | | Costello Athletic Center · Lowell, MA |
| 20 | Thu Jan 22 | vsVermont | TBD | 21-12 | .636 | - | | Costello Athletic Center · Lowell, MA |
| 21 | Sat Jan 24 | atUMBC | TBD | 13-19 | .406 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 22 | Thu Jan 29 | atNew Hampshire | TBD | 8-24 | .250 | - | | Lundholm Gymnasium · Durham, NH |
| 23 | Sat Jan 31 | vsMaine | TBD | 20-14 | .588 | - | | Costello Athletic Center · Lowell, MA |
| 24 | Thu Feb 5 | atNJIT | TBD | 6-25 | .194 | - | | NJIT Wellness and Events Center · Newark, NJ |
| 25 | Sat Feb 7 | atAlbany | TBD | 17-16 | .515 | - | | SEFCU Arena · Albany, NY |
| 26 | Thu Feb 12 | vsBryant | TBD | 23-12 | .657 | - | | Costello Athletic Center · Lowell, MA |
| 27 | Thu Feb 19 | vsNew Hampshire | TBD | 8-24 | .250 | - | | Costello Athletic Center · Lowell, MA |
| 28 | Sat Feb 21 | vsBinghamton | TBD | 15-17 | .469 | - | | Costello Athletic Center · Lowell, MA |
| 29 | Thu Feb 26 | atVermont | 7:00 PM | 21-12 | .636 | - | | Patrick Gymnasium · Burlington, VT |
| 30 | Sat Feb 28 | vsUMBC | TBD | 13-19 | .406 | - | | Costello Athletic Center · Lowell, MA |
| 31 | Tue Mar 3 | atMaine | TBD | 20-14 | .588 | - | | Cross Insurance Center · Bangor, ME |
