| 1 | Tue Nov 9 | vs TBD | W91-55 | 1-0 | 1.000 | - | | Costello Athletic Center · Lowell, MA |
| 2 | Sat Nov 13 | at Dayton | W59-58 | 2-0 | 1.000 | - | | UD Arena · Dayton, OH |
| 3 | Tue Nov 16 | at Oklahoma St | L58-80 | 2-1 | .667 | - | | Gallagher-Iba Arena · Stillwater, OK |
| 4 | Wed Nov 17 | vs C Connecticut | W77-53 | 3-1 | .750 | - | | Costello Athletic Center · Lowell, MA |
| 5 | Fri Nov 19 | at G Washington | W67-56 | 4-1 | .800 | - | | Charles E. Smith Center · Washington, D.C. |
| 6 | Wed Nov 24 | at UMass | L81-92 | 4-2 | .667 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 7 | Sat Nov 27 | vsTBD | W101-38 | 5-2 | .714 | - | | Costello Athletic Center · Lowell, MA |
| 8 | Wed Dec 1 | vs Brown | L63-73 | 5-3 | .625 | - | | Costello Athletic Center · Lowell, MA |
| 9 | Sat Dec 4 | at Merrimack | W61-57 | 6-3 | .667 | - | | placeholder · sf, ca |
| 10 | Wed Dec 8 | at Boston Univ | L62-72 | 6-4 | .600 | - | | Case Gym · Boston, MA |
| 11 | Sat Dec 11 | vsTBD | W109-45 | 7-4 | .636 | - | | Costello Athletic Center · Lowell, MA |
| 12 | Sun Dec 19 | vs Sacred Heart | W70-62 | 8-4 | .667 | - | | Costello Athletic Center · Lowell, MA |
| 15 | Sun Jan 2 | at Binghamton | L63-68 | 8-5 | .615 | - | | Events Center (Binghamton) · Binghamton, NY |
| 16 | Thu Jan 6 | vs NJIT | L72-77 | 8-6 | .571 | - | | Costello Athletic Center · Lowell, MA |
| 17 | Sat Jan 8 | at UMBC | W66-64 | 9-6 | .600 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 18 | Wed Jan 12 | at Albany | L47-57 | 9-7 | .563 | - | | SEFCU Arena · Albany, NY |
| 19 | Sat Jan 15 | vsTBD | PPD | 15-16 | .484 | - | | Costello Athletic Center · Lowell, MA |
| 20 | Wed Jan 19 | vs Maine | W71-62 | 10-7 | .588 | - | | Costello Athletic Center · Lowell, MA |
| 21 | Sat Jan 22 | at New Hampshire | L61-67 | 10-8 | .556 | - | | Lundholm Gymnasium · Durham, NH |
| 22 | Wed Jan 26 | vsAlbany | L62-64 (OT) | 10-9 | .526 | - | | Costello Athletic Center · Lowell, MA |
| 23 | Sat Jan 29 | atTBD | PPD | 15-16 | .484 | - | | Chase Arena |
| 24 | Wed Feb 2 | atMaine | W62-50 | 11-9 | .550 | - | | Cross Insurance Center · Bangor, ME |
| 25 | Sat Feb 5 | vs Vermont | L67-78 | 11-10 | .524 | - | | Costello Athletic Center · Lowell, MA |
| 26 | Mon Feb 7 | vsTBD | W85-75 | 12-10 | .545 | - | | Costello Athletic Center · Lowell, MA |
| 27 | Wed Feb 9 | at Stony Brook | L85-87 | 12-11 | .522 | - | | Island FCU Arena · Stony Brook, NY |
| 28 | Sat Feb 12 | vsUMBC | W88-71 | 13-11 | .542 | - | | Costello Athletic Center · Lowell, MA |
| 29 | Wed Feb 16 | atNJIT | L55-59 | 13-12 | .520 | - | | NJIT Wellness and Events Center · Newark, NJ |
| 30 | Sat Feb 19 | vsBinghamton | L64-78 | 13-13 | .500 | - | | Costello Athletic Center · Lowell, MA |
| 31 | Wed Feb 23 | vsStony Brook | W67-50 | 14-13 | .519 | - | | Costello Athletic Center · Lowell, MA |
| 32 | Sat Feb 26 | atVermont | L61-62 | 14-14 | .500 | - | | Patrick Gymnasium · Burlington, VT |
| 33 | Tue Mar 1 | vsNew Hampshire | L48-64 | 14-15 | .483 | - | | Costello Athletic Center · Lowell, MA |
| 34 | Thu Mar 3 | atTBD | W83-73 | 15-15 | .500 | - | | Chase Arena |
| 35 | Sun Mar 6 | atUMBC | L85-93 (OT) | 15-16 | .484 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
Long Island
St Francis BK