| 1 | Wed Nov 6 | vs McNeese | W75-65 | -7½ | 1-0 | 1.000 | - | | University Arena (MI) · Kalamazoo, MI |
| 2 | Sat Nov 9 | atMilwaukee | W115-110 (3OT) | +2 | 2-0 | 1.000 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 3 | Tue Nov 12 | vsMiss Valley St | W91-81 | -28½ | 3-0 | 1.000 | - | | University Arena (MI) · Kalamazoo, MI |
| 4 | Fri Nov 15 | atOle Miss | L58-85 | +19½ | 3-1 | .750 | - | | SJB Pavilion · Oxford, MS |
| 5 | Tue Nov 19 | vsTBD | W102-56 | - | 4-1 | .800 | - | | University Arena (MI) · Kalamazoo, MI |
| 6 | Fri Nov 22 | atOklahoma St | L63-70 | +18½ | 4-2 | .667 | - | | Gallagher-Iba Arena · Stillwater, OK |
| 7 | Mon Nov 25 | atYale | L51-73 | +7 | 4-3 | .571 | - | ESPNU | John J. Lee Amphitheater · New Haven, CT |
| 8 | Tue Nov 26 | atSeattle U | L55-59 | +1 | 4-4 | .500 | - | ESPNU | Redhawk Center · Seattle, WA |
| 9 | Tue Dec 3 | vsOakland | L62-72 | +1 | 4-5 | .444 | - | | University Arena (MI) · Kalamazoo, MI |
| 10 | Sat Dec 7 | vsYoungstown St | W66-64 | -2 | 5-5 | .500 | - | | University Arena (MI) · Kalamazoo, MI |
| 11 | Sat Dec 14 | atManhattan | W59-58 | +4 | 6-5 | .545 | - | | Draddy Gymnasium · Riverdale, NY |
| 12 | Wed Dec 18 | vsTBD | W84-61 | - | 7-5 | .583 | - | | University Arena (MI) · Kalamazoo, MI |
| 13 | Sun Dec 29 | at14Michigan St | L62-95 | +25½ | 7-6 | .538 | - | Big Ten Network | Breslin Center · East Lansing, MI |
| 14 | Sat Jan 4 | vsOhio | W77-65 | +1½ | 8-6 | .571 | - | | University Arena (MI) · Kalamazoo, MI |
| 15 | Tue Jan 7 | atAkron | L69-84 | +11½ | 8-7 | .533 | - | | James A. Rhodes Arena · Akron, OH |
| 16 | Sat Jan 11 | atToledo | L59-67 | +11½ | 8-8 | .500 | - | | Savage Arena · Toledo, OH |
| 17 | Tue Jan 14 | vsBowling Green | L82-85 | +4 | 8-9 | .471 | - | | University Arena (MI) · Kalamazoo, MI |
| 18 | Sat Jan 18 | vsKent State | W67-63 | +5½ | 9-9 | .500 | - | | University Arena (MI) · Kalamazoo, MI |
| 19 | Tue Jan 21 | atBuffalo | L79-90 | +9½ | 9-10 | .474 | - | | Alumni Arena · Buffalo, NY |
| 20 | Sat Jan 25 | atN Illinois | L52-58 | +5½ | 9-11 | .450 | - | | NIU Convocation Center · Dekalb, IL |
| 21 | Sat Feb 1 | vsC Michigan | L78-85 | +1½ | 9-12 | .429 | - | | University Arena (MI) · Kalamazoo, MI |
| 22 | Tue Feb 4 | atMiami OH | W64-60 | +5 | 10-12 | .455 | - | | Millett Hall · Oxford, OH |
| 23 | Sat Feb 8 | vsBall State | W68-64 | +5½ | 11-12 | .478 | - | | University Arena (MI) · Kalamazoo, MI |
| 24 | Tue Feb 11 | atOhio | L61-73 | +7 | 11-13 | .458 | - | | Convocation Center (OH) · Athens, OH |
| 25 | Sat Feb 15 | atE Michigan | L51-69 | +5½ | 11-14 | .440 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 26 | Tue Feb 18 | vsAkron | L67-71 | +8 | 11-15 | .423 | - | | University Arena (MI) · Kalamazoo, MI |
| 27 | Sat Feb 22 | vsToledo | L59-68 | +3½ | 11-16 | .407 | - | | University Arena (MI) · Kalamazoo, MI |
| 28 | Tue Feb 25 | atBall State | L61-71 | +9½ | 11-17 | .393 | - | | Worthen Arena · Muncie, IN |
| 29 | Sat Feb 29 | vsN Illinois | W72-69 | +1½ | 12-17 | .414 | - | | University Arena (MI) · Kalamazoo, MI |
| 30 | Tue Mar 3 | vsE Michigan | W70-54 | +2½ | 13-17 | .433 | - | | University Arena (MI) · Kalamazoo, MI |
| 31 | Fri Mar 6 | atC Michigan | L68-85 | +7 | 13-18 | .419 | - | | McGuirk Arena · Mount Pleasant, MI |
| 32 | Mon Mar 9 | atToledo | L73-76 | +10 | 13-19 | .406 | - | | Savage Arena · Toledo, OH |
