| 1 | Mon Nov 3 | vs Coast Car | W76-71 | 1-0 | 1.000 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 2 | Thu Nov 6 | vsTBD | L81-85 | 1-1 | .500 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 3 | Sun Nov 9 | atCampbell | L82-91 | 1-2 | .333 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 4 | Wed Nov 12 | vsPurdue FW | W83-71 | 2-2 | .500 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 5 | Sun Nov 16 | atSouth Dakota | L78-83 | 2-3 | .400 | - | | Sanford Coyote Sports Center · Vermillion, SD |
| 6 | Thu Nov 20 | atOhio State | L58-91 | 2-4 | .333 | - | BTN | Value City Arena · Columbus, OH |
| 7 | Sun Nov 23 | vsMount St Mary | W83-60 | 3-4 | .429 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 8 | Sat Nov 29 | atValparaiso | L55-84 | 3-5 | .375 | - | ESPN+ | Athletics-Recreation Center · Valparaiso, IN |
| 9 | Wed Dec 3 | vsSo Indiana | W88-74 | 4-5 | .444 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 10 | Sat Dec 6 | atSIUE | W83-73 | 5-5 | .500 | - | ESPN+ | First Community Arena at the Vadalabene Center · Edwardsville, IL |
| 11 | Sun Dec 14 | atIowa | L51-91 | 5-6 | .455 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 12 | Sat Dec 20 | vsBuffalo | L71-88 | 5-7 | .417 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 13 | Mon Dec 22 | vsTBD | W94-57 | 6-7 | .462 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 14 | Tue Dec 30 | atToledo | L79-84 | 6-8 | .429 | - | ESPN+ | Savage Arena · Toledo, OH |
| 15 | Tue Jan 6 | atMiami OH | L76-87 | 6-9 | .400 | - | ESPN+ | Millett Hall · Oxford, OH |
| 16 | Sat Jan 10 | vsE Michigan | W79-62 | 7-9 | .438 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 17 | Tue Jan 13 | vsUMass | L82-85 | 7-10 | .412 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 18 | Sat Jan 17 | atAkron | L89-104 | 7-11 | .389 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 19 | Tue Jan 20 | vsBowling Green | L54-72 | 7-12 | .368 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 20 | Sat Jan 24 | vsC Michigan | W77-65 | 8-12 | .400 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 21 | Tue Jan 27 | atN Illinois | L65-85 | 8-13 | .381 | - | ESPN+ | NIU Convocation Center · Dekalb, IL |
| 22 | Tue Feb 3 | atOhio | L71-91 | 8-14 | .364 | - | ESPN+ | Convocation Center (OH) · Athens, OH |
| 23 | Sat Feb 7 | atTexas St | L61-77 | 8-15 | .348 | - | ESPN+ | Strahan Arena · San Marcos, TX |
| 24 | Wed Feb 11 | vsToledo | L79-90 | 8-16 | .333 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 25 | Sat Feb 14 | atE Michigan | W76-62 | 9-16 | .360 | - | ESPN+ | Convocation Center (MI) · Ypsilanti, MI |
| 26 | Tue Feb 17 | vsAkron | L73-90 | 9-17 | .346 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 27 | Sat Feb 21 | atC Michigan | L70-83 | 9-18 | .333 | - | ESPN+ | McGuirk Arena · Mount Pleasant, MI |
| 28 | Tue Feb 24 | atBowling Green | W88-79 | 10-18 | .357 | - | ESPN+ | Stroh Center · Bowling Green, OH |
| 29 | Fri Feb 27 | vs21Miami OH | L67-69 | 10-19 | .345 | - | CBSSN | University Arena (MI) · Kalamazoo, MI |
