| 1 | Wed Oct 12 | at Oilers | L3-5 | 0-1-0 | 0 PTS | Rogers Place · Edmonton, AB |
| 2 | Sat Oct 15 | atFlyers | L2-3 | 0-2-0 | 0 PTS | Wells Fargo Center · Philadelphia, PA |
| 3 | Mon Oct 17 | atCapitals | L4-6 | 0-3-0 | 0 PTS | Capital One Arena · Washington, D.C. |
| 4 | Tue Oct 18 | atJackets | L3-4 (OT) | 0-3-1 | 1 PTS | Nationwide Arena · Columbus, OH |
| 5 | Thu Oct 20 | atWild | L3-4 (OT) | 0-3-2 | 2 PTS | Xcel Energy Center · St. Paul, MN |
| 6 | Sat Oct 22 | vsSabres | L1-5 | 0-4-2 | 2 PTS | Rogers Arena · Vancouver, British Columbia |
| 7 | Mon Oct 24 | vsHurricanes | L2-3 | 0-5-2 | 2 PTS | Rogers Arena · Vancouver, British Columbia |
| 8 | Thu Oct 27 | atKraken | W5-4 | 1-5-2 | 4 PTS | Climate Pledge Arena · Seattle, WA |
| 9 | Fri Oct 28 | vsPenguins | W5-1 | 2-5-2 | 6 PTS | Rogers Arena · Vancouver, British Columbia |
| 10 | Tue Nov 1 | vsDevils | L2-5 | 2-6-2 | 6 PTS | Rogers Arena · Vancouver, British Columbia |
| 11 | Thu Nov 3 | vsDucks | W8-5 | 3-6-2 | 8 PTS | Rogers Arena · Vancouver, British Columbia |
| 12 | Sat Nov 5 | vsPredators | L3-4 (SO) | 3-6-3 | 9 PTS | Rogers Arena · Vancouver, British Columbia |
| 13 | Tue Nov 8 | atSenators | W6-4 | 4-6-3 | 11 PTS | Canadian Tire Centre · Ottawa, ON |
| 14 | Wed Nov 9 | atCanadiens | L2-5 | 4-7-3 | 11 PTS | Bell Centre · Montreal, QC |
| 15 | Sat Nov 12 | atMaple Leafs | L2-3 | 4-8-3 | 11 PTS | Scotiabank Arena · Toronto, ON |
| 16 | Sun Nov 13 | atBruins | L2-5 | 4-9-3 | 11 PTS | TD Garden · Boston, MA |
| 17 | Tue Nov 15 | atSabres | W5-4 | 5-9-3 | 13 PTS | KeyBank Center · Buffalo, NY |
| 18 | Fri Nov 18 | vsKings | W4-1 | 6-9-3 | 15 PTS | Rogers Arena · Vancouver, British Columbia |
| 19 | Mon Nov 21 | vsKnights | L4-5 | 6-10-3 | 15 PTS | Rogers Arena · Vancouver, British Columbia |
| 20 | Wed Nov 23 | atAvalanche | W4-3 | 7-10-3 | 17 PTS | Ball Arena · Denver, CO |
| 21 | Sat Nov 26 | atKnights | W5-1 | 8-10-3 | 19 PTS | T-Mobile Arena · Las Vegas, NV |
| 22 | Sun Nov 27 | atSharks | W4-3 (OT) | 9-10-3 | 21 PTS | SAP Center · San Jose, CA |
| 23 | Tue Nov 29 | vsCapitals | L1-5 | 9-11-3 | 21 PTS | Rogers Arena · Vancouver, British Columbia |
| 24 | Thu Dec 1 | vsPanthers | L1-5 | 9-12-3 | 21 PTS | Rogers Arena · Vancouver, British Columbia |
| 25 | Sat Dec 3 | vsCoyotes | W3-2 (OT) | 10-12-3 | 23 PTS | Rogers Arena · Vancouver, British Columbia |
| 26 | Mon Dec 5 | vsCanadiens | W7-6 (OT) | 11-12-3 | 25 PTS | Rogers Arena · Vancouver, British Columbia |
| 27 | Wed Dec 7 | atSharks | W6-5 (OT) | 12-12-3 | 27 PTS | SAP Center · San Jose, CA |
| 28 | Sat Dec 10 | vsWild | L0-3 | 12-13-3 | 27 PTS | Rogers Arena · Vancouver, British Columbia |
| 29 | Wed Dec 14 | atFlames | W4-3 (SO) | 13-13-3 | 29 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 30 | Sat Dec 17 | vsJets | L1-5 | 13-14-3 | 29 PTS | Rogers Arena · Vancouver, British Columbia |
| 31 | Mon Dec 19 | vsBlues | L1-5 | 13-15-3 | 29 PTS | Rogers Arena · Vancouver, British Columbia |
| 32 | Thu Dec 22 | vsKraken | W6-5 (SO) | 14-15-3 | 31 PTS | Rogers Arena · Vancouver, British Columbia |
| 33 | Fri Dec 23 | atOilers | W5-2 | 15-15-3 | 33 PTS | Rogers Place · Edmonton, AB |
| 34 | Tue Dec 27 | vsSharks | W6-2 | 16-15-3 | 35 PTS | Rogers Arena · Vancouver, British Columbia |
| 35 | Thu Dec 29 | atJets | L2-4 | 16-16-3 | 35 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 36 | Sat Dec 31 | atFlames | L2-3 | 16-17-3 | 35 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 37 | Tue Jan 3 | vsIslanders | L2-6 | 16-18-3 | 35 PTS | Rogers Arena · Vancouver, British Columbia |
| 38 | Thu Jan 5 | vsAvalanche | W4-2 | 17-18-3 | 37 PTS | Rogers Arena · Vancouver, British Columbia |
| 39 | Sun Jan 8 | atJets | L4-7 | 17-19-3 | 37 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 40 | Tue Jan 10 | atPenguins | L4-5 | 17-20-3 | 37 PTS | PPG Paints Arena · Pittsburgh, PA |
| 41 | Thu Jan 12 | atLightning | L4-5 | 17-21-3 | 37 PTS | AMALIE Arena · Tampa, FL |
| 42 | Sat Jan 14 | atPanthers | L3-4 | 17-22-3 | 37 PTS | Amerant Bank Arena · Sunrise, FL |
| 43 | Sun Jan 15 | atHurricanes | W4-3 (SO) | 18-22-3 | 39 PTS | PNC Arena · Raleigh, NC |
| 44 | Wed Jan 18 | vsLightning | L2-5 | 18-23-3 | 39 PTS | Rogers Arena · Vancouver, British Columbia |
| 45 | Fri Jan 20 | vsAvalanche | L1-4 | 18-24-3 | 39 PTS | Rogers Arena · Vancouver, British Columbia |
| 46 | Sat Jan 21 | vsOilers | L2-4 | 18-25-3 | 39 PTS | Rogers Arena · Vancouver, British Columbia |
| 47 | Tue Jan 24 | vsBlackhawks | W5-2 | 19-25-3 | 41 PTS | Rogers Arena · Vancouver, British Columbia |
| 48 | Wed Jan 25 | atKraken | L1-6 | 19-26-3 | 41 PTS | Climate Pledge Arena · Seattle, WA |
| 49 | Fri Jan 27 | vsJackets | W5-2 | 20-26-3 | 43 PTS | Rogers Arena · Vancouver, British Columbia |
| 50 | Mon Feb 6 | atDevils | L4-5 (OT) | 20-26-4 | 44 PTS | Prudential Center · Newark, NJ |
| 51 | Wed Feb 8 | atRangers | L3-4 | 20-27-4 | 44 PTS | Madison Square Garden · Manhattan, NY |
| 52 | Thu Feb 9 | atIslanders | W6-5 | 21-27-4 | 46 PTS | UBS Arena · Elmont, NY |
| 53 | Sat Feb 11 | atRed Wings | L2-5 | 21-28-4 | 46 PTS | Little Caesars Arena · Detroit, MI |
| 54 | Mon Feb 13 | vsRed Wings | L1-6 | 21-29-4 | 46 PTS | Rogers Arena · Vancouver, British Columbia |
| 55 | Wed Feb 15 | vsRangers | L4-6 | 21-30-4 | 46 PTS | Rogers Arena · Vancouver, British Columbia |
| 56 | Sat Feb 18 | vsFlyers | W6-2 | 22-30-4 | 48 PTS | Rogers Arena · Vancouver, British Columbia |
| 57 | Tue Feb 21 | atPredators | L4-5 (SO) | 22-30-5 | 49 PTS | Bridgestone Arena · Nashville, TN |
| 58 | Thu Feb 23 | atBlues | W3-2 (OT) | 23-30-5 | 51 PTS | Enterprise Center · St. Louis, MO |
| 59 | Sat Feb 25 | vsBruins | L1-3 | 23-31-5 | 51 PTS | Rogers Arena · Vancouver, British Columbia |
| 60 | Mon Feb 27 | atStars | W5-4 (OT) | 24-31-5 | 53 PTS | American Airlines Center · Dallas, TX |
| 61 | Thu Mar 2 | vsWild | L1-2 | 24-32-5 | 53 PTS | Rogers Arena · Vancouver, British Columbia |
| 62 | Sat Mar 4 | vsMaple Leafs | W4-1 | 25-32-5 | 55 PTS | Rogers Arena · Vancouver, British Columbia |
| 63 | Mon Mar 6 | vsPredators | W4-3 (SO) | 26-32-5 | 57 PTS | Rogers Arena · Vancouver, British Columbia |
| 64 | Wed Mar 8 | vsDucks | W3-2 (OT) | 27-32-5 | 59 PTS | Rogers Arena · Vancouver, British Columbia |
| 65 | Sat Mar 11 | vsSenators | W5-2 | 28-32-5 | 61 PTS | Rogers Arena · Vancouver, British Columbia |
| 66 | Tue Mar 14 | vsStars | W5-2 | 29-32-5 | 63 PTS | Rogers Arena · Vancouver, British Columbia |
| 67 | Thu Mar 16 | atCoyotes | L2-3 | 29-33-5 | 63 PTS | Mullett Arena · Tempe, AZ |
| 68 | Sat Mar 18 | atKings | W3-2 (SO) | 30-33-5 | 65 PTS | Crypto.com Arena · Los Angeles, CA |
| 69 | Sun Mar 19 | atDucks | W2-1 | 31-33-5 | 67 PTS | Honda Center · Anaheim, CA |
| 70 | Tue Mar 21 | vsKnights | L3-4 | 31-34-5 | 67 PTS | Rogers Arena · Vancouver, British Columbia |
| 71 | Thu Mar 23 | vsSharks | W7-2 | 32-34-5 | 69 PTS | Rogers Arena · Vancouver, British Columbia |
| 72 | Sat Mar 25 | atStars | W3-1 | 33-34-5 | 71 PTS | American Airlines Center · Dallas, TX |
| 73 | Sun Mar 26 | atBlackhawks | W4-2 | 34-34-5 | 73 PTS | United Center · Chicago, IL |
| 74 | Tue Mar 28 | atBlues | L5-6 (OT) | 34-34-6 | 74 PTS | Enterprise Center · St. Louis, MO |
| 75 | Fri Mar 31 | vsFlames | L4-5 (OT) | 34-34-7 | 75 PTS | Rogers Arena · Vancouver, British Columbia |
| 76 | Sun Apr 2 | vsKings | L1-4 | 34-35-7 | 75 PTS | Rogers Arena · Vancouver, British Columbia |
| 77 | Tue Apr 4 | vsKraken | L2-5 | 34-36-7 | 75 PTS | Rogers Arena · Vancouver, British Columbia |
| 78 | Thu Apr 6 | vsBlackhawks | W3-0 | 35-36-7 | 77 PTS | Rogers Arena · Vancouver, British Columbia |
| 79 | Sat Apr 8 | vsFlames | W3-2 (SO) | 36-36-7 | 79 PTS | Rogers Arena · Vancouver, British Columbia |
| 80 | Mon Apr 10 | atKings | L0-3 | 36-37-7 | 79 PTS | Crypto.com Arena · Los Angeles, CA |
| 81 | Tue Apr 11 | atDucks | W3-2 | 37-37-7 | 81 PTS | Honda Center · Anaheim, CA |
| 82 | Thu Apr 13 | atCoyotes | W5-4 (OT) | 38-37-7 | 83 PTS | Mullett Arena · Tempe, AZ |
