| 1 | Wed Oct 12 | vs Bruins | L2-5 | 0-1-0 | 0 PTS | Capital One Arena · Washington, D.C. |
| 2 | Thu Oct 13 | atMaple Leafs | L2-3 | 0-2-0 | 0 PTS | Scotiabank Arena · Toronto, ON |
| 3 | Sat Oct 15 | vsCanadiens | W3-1 | 1-2-0 | 2 PTS | Capital One Arena · Washington, D.C. |
| 4 | Mon Oct 17 | vsCanucks | W6-4 | 2-2-0 | 4 PTS | Capital One Arena · Washington, D.C. |
| 5 | Thu Oct 20 | atSenators | L2-5 | 2-3-0 | 4 PTS | Canadian Tire Centre · Ottawa, ON |
| 6 | Sat Oct 22 | vsKings | W4-3 | 3-3-0 | 6 PTS | Capital One Arena · Washington, D.C. |
| 7 | Mon Oct 24 | atDevils | W6-3 | 4-3-0 | 8 PTS | Prudential Center · Newark, NJ |
| 8 | Thu Oct 27 | atStars | L0-2 | 4-4-0 | 8 PTS | American Airlines Center · Dallas, TX |
| 9 | Sat Oct 29 | atPredators | W3-0 | 5-4-0 | 10 PTS | Bridgestone Arena · Nashville, TN |
| 10 | Mon Oct 31 | atHurricanes | L2-3 (SO) | 5-4-1 | 11 PTS | PNC Arena · Raleigh, NC |
| 11 | Tue Nov 1 | vsKnights | L2-3 (OT) | 5-4-2 | 12 PTS | Capital One Arena · Washington, D.C. |
| 12 | Thu Nov 3 | atRed Wings | L1-3 | 5-5-2 | 12 PTS | Little Caesars Arena · Detroit, MI |
| 13 | Sat Nov 5 | vsCoyotes | L2-3 | 5-6-2 | 12 PTS | Capital One Arena · Washington, D.C. |
| 14 | Mon Nov 7 | vsOilers | W5-4 | 6-6-2 | 14 PTS | Capital One Arena · Washington, D.C. |
| 15 | Wed Nov 9 | vsPenguins | L1-4 | 6-7-2 | 14 PTS | Capital One Arena · Washington, D.C. |
| 16 | Fri Nov 11 | vsLightning | W5-1 | 7-7-2 | 16 PTS | Capital One Arena · Washington, D.C. |
| 17 | Sun Nov 13 | atLightning | L3-6 | 7-8-2 | 16 PTS | AMALIE Arena · Tampa, FL |
| 18 | Tue Nov 15 | atPanthers | L2-5 | 7-9-2 | 16 PTS | Amerant Bank Arena · Sunrise, FL |
| 19 | Thu Nov 17 | atBlues | L4-5 (SO) | 7-9-3 | 17 PTS | Enterprise Center · St. Louis, MO |
| 20 | Sat Nov 19 | vsAvalanche | L0-4 | 7-10-3 | 17 PTS | Capital One Arena · Washington, D.C. |
| 21 | Wed Nov 23 | vsFlyers | W3-2 (OT) | 8-10-3 | 19 PTS | Capital One Arena · Washington, D.C. |
| 22 | Fri Nov 25 | vsFlames | W3-0 | 9-10-3 | 21 PTS | Capital One Arena · Washington, D.C. |
| 23 | Sat Nov 26 | atDevils | L1-5 | 9-11-3 | 21 PTS | Prudential Center · Newark, NJ |
| 24 | Tue Nov 29 | atCanucks | W5-1 | 10-11-3 | 23 PTS | Rogers Arena · Vancouver, British Columbia |
| 25 | Thu Dec 1 | atKraken | L2-3 (OT) | 10-11-4 | 24 PTS | Climate Pledge Arena · Seattle, WA |
| 26 | Sat Dec 3 | atFlames | L2-5 | 10-12-4 | 24 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 27 | Mon Dec 5 | atOilers | W3-2 | 11-12-4 | 26 PTS | Rogers Place · Edmonton, AB |
| 28 | Wed Dec 7 | atFlyers | W4-1 | 12-12-4 | 28 PTS | Wells Fargo Center · Philadelphia, PA |
| 29 | Fri Dec 9 | vsKraken | W4-1 | 13-12-4 | 30 PTS | Capital One Arena · Washington, D.C. |
| 30 | Sun Dec 11 | atJets | W5-2 | 14-12-4 | 32 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 31 | Tue Dec 13 | atBlackhawks | W7-3 | 15-12-4 | 34 PTS | United Center · Chicago, IL |
| 32 | Thu Dec 15 | vsStars | L1-2 | 15-13-4 | 34 PTS | Capital One Arena · Washington, D.C. |
| 33 | Sat Dec 17 | vsMaple Leafs | W5-2 | 16-13-4 | 36 PTS | Capital One Arena · Washington, D.C. |
| 34 | Mon Dec 19 | vsRed Wings | W4-3 (OT) | 17-13-4 | 38 PTS | Capital One Arena · Washington, D.C. |
| 35 | Thu Dec 22 | atSenators | W3-2 (OT) | 18-13-4 | 40 PTS | Canadian Tire Centre · Ottawa, ON |
| 36 | Fri Dec 23 | vsJets | W4-1 | 19-13-4 | 42 PTS | Capital One Arena · Washington, D.C. |
| 37 | Tue Dec 27 | atRangers | W4-0 | 20-13-4 | 44 PTS | Madison Square Garden · Manhattan, NY |
| 38 | Thu Dec 29 | vsSenators | L3-4 (OT) | 20-13-5 | 45 PTS | Capital One Arena · Washington, D.C. |
| 39 | Sat Dec 31 | vsCanadiens | W9-2 | 21-13-5 | 47 PTS | Capital One Arena · Washington, D.C. |
| 40 | Tue Jan 3 | vsSabres | L4-5 (OT) | 21-13-6 | 48 PTS | Capital One Arena · Washington, D.C. |
| 41 | Thu Jan 5 | atJackets | W6-2 | 22-13-6 | 50 PTS | Nationwide Arena · Columbus, OH |
| 42 | Fri Jan 6 | vsPredators | L2-3 | 22-14-6 | 50 PTS | Capital One Arena · Washington, D.C. |
| 43 | Sun Jan 8 | vsJackets | W1-0 | 23-14-6 | 52 PTS | Capital One Arena · Washington, D.C. |
| 44 | Wed Jan 11 | atFlyers | L3-5 | 23-15-6 | 52 PTS | Wells Fargo Center · Philadelphia, PA |
| 45 | Sat Jan 14 | vsFlyers | L1-3 | 23-16-6 | 52 PTS | Capital One Arena · Washington, D.C. |
| 46 | Mon Jan 16 | atIslanders | W4-3 (OT) | 24-16-6 | 54 PTS | UBS Arena · Elmont, NY |
| 47 | Tue Jan 17 | vsWild | L2-4 | 24-17-6 | 54 PTS | Capital One Arena · Washington, D.C. |
| 48 | Thu Jan 19 | atCoyotes | W4-0 | 25-17-6 | 56 PTS | Mullett Arena · Tempe, AZ |
| 49 | Sat Jan 21 | atKnights | L2-6 | 25-18-6 | 56 PTS | T-Mobile Arena · Las Vegas, NV |
| 50 | Tue Jan 24 | atAvalanche | L2-3 | 25-19-6 | 56 PTS | Ball Arena · Denver, CO |
| 51 | Thu Jan 26 | vsPenguins | W3-2 (SO) | 26-19-6 | 58 PTS | Capital One Arena · Washington, D.C. |
| 52 | Sun Jan 29 | atMaple Leafs | L1-5 | 26-20-6 | 58 PTS | Scotiabank Arena · Toronto, ON |
| 53 | Tue Jan 31 | atJackets | W4-3 (OT) | 27-20-6 | 60 PTS | Nationwide Arena · Columbus, OH |
| 54 | Sat Feb 11 | atBruins | W2-1 | 28-20-6 | 62 PTS | TD Garden · Boston, MA |
| 55 | Sun Feb 12 | vsSharks | L1-4 | 28-21-6 | 62 PTS | Capital One Arena · Washington, D.C. |
| 56 | Tue Feb 14 | vsHurricanes | L2-3 | 28-22-6 | 62 PTS | Capital One Arena · Washington, D.C. |
| 57 | Thu Feb 16 | vsPanthers | L3-6 | 28-23-6 | 62 PTS | Capital One Arena · Washington, D.C. |
| 58 | Sat Feb 18 | atHurricanes | L1-4 | 28-24-6 | 62 PTS | PNC Arena · Raleigh, NC |
| 59 | Tue Feb 21 | vsRed Wings | L1-3 | 28-25-6 | 62 PTS | Capital One Arena · Washington, D.C. |
| 60 | Thu Feb 23 | vsDucks | L2-4 | 28-26-6 | 62 PTS | Capital One Arena · Washington, D.C. |
| 61 | Sat Feb 25 | vsRangers | W6-3 | 29-26-6 | 64 PTS | Capital One Arena · Washington, D.C. |
| 62 | Sun Feb 26 | atSabres | L4-7 | 29-27-6 | 64 PTS | KeyBank Center · Buffalo, NY |
| 63 | Wed Mar 1 | atDucks | W3-2 (OT) | 30-27-6 | 66 PTS | Honda Center · Anaheim, CA |
| 64 | Sat Mar 4 | atSharks | W8-3 | 31-27-6 | 68 PTS | SAP Center · San Jose, CA |
| 65 | Mon Mar 6 | atKings | L2-4 | 31-28-6 | 68 PTS | Crypto.com Arena · Los Angeles, CA |
| 66 | Thu Mar 9 | vsDevils | L2-3 (SO) | 31-28-7 | 69 PTS | Capital One Arena · Washington, D.C. |
| 67 | Sat Mar 11 | atIslanders | W5-1 | 32-28-7 | 71 PTS | UBS Arena · Elmont, NY |
| 68 | Tue Mar 14 | atRangers | L3-5 | 32-29-7 | 71 PTS | Madison Square Garden · Manhattan, NY |
| 69 | Wed Mar 15 | vsSabres | W5-4 (SO) | 33-29-7 | 73 PTS | Capital One Arena · Washington, D.C. |
| 70 | Fri Mar 17 | vsBlues | L2-5 | 33-30-7 | 73 PTS | Capital One Arena · Washington, D.C. |
| 71 | Sun Mar 19 | atWild | L3-5 | 33-31-7 | 73 PTS | Xcel Energy Center · St. Paul, MN |
| 72 | Tue Mar 21 | vsJackets | L6-7 (OT) | 33-31-8 | 74 PTS | Capital One Arena · Washington, D.C. |
| 73 | Thu Mar 23 | vsBlackhawks | W6-1 | 34-31-8 | 76 PTS | Capital One Arena · Washington, D.C. |
| 74 | Sat Mar 25 | atPenguins | L3-4 | 34-32-8 | 76 PTS | PPG Paints Arena · Pittsburgh, PA |
| 75 | Wed Mar 29 | vsIslanders | L1-2 (SO) | 34-32-9 | 77 PTS | Capital One Arena · Washington, D.C. |
| 76 | Thu Mar 30 | atLightning | L1-5 | 34-33-9 | 77 PTS | AMALIE Arena · Tampa, FL |
| 77 | Sun Apr 2 | vsRangers | L2-5 | 34-34-9 | 77 PTS | Capital One Arena · Washington, D.C. |
| 78 | Thu Apr 6 | atCanadiens | L2-6 | 34-35-9 | 77 PTS | Bell Centre · Montreal, QC |
| 79 | Sat Apr 8 | vsPanthers | L2-4 | 34-36-9 | 77 PTS | Capital One Arena · Washington, D.C. |
| 80 | Mon Apr 10 | vsIslanders | W5-2 | 35-36-9 | 79 PTS | Capital One Arena · Washington, D.C. |
| 81 | Tue Apr 11 | atBruins | L2-5 | 35-37-9 | 79 PTS | TD Garden · Boston, MA |
| 82 | Thu Apr 13 | vsDevils | L4-5 (OT) | 35-37-10 | 80 PTS | Capital One Arena · Washington, D.C. |
