| 1 | Sat Aug 16 | at Spurs | L0-3 | 0-0-1 | 0 PTS | Tottenham Hotspur Stadium · London, England |
| 2 | Sat Aug 23 | vsSunderland | W2-0 | 1-0-1 | 3 PTS | Turf Moor · Burnley, England |
| 3 | Sat Aug 30 | atMan Utd | L2-3 | 1-0-2 | 3 PTS | Old Trafford · Manchester, England |
| 4 | Sun Sep 14 | vsLiverpool | L0-1 | 1-0-3 | 3 PTS | Turf Moor · Burnley, England |
| 5 | Sat Sep 20 | vsNott'm Forest | D1-1 | 1-1-3 | 4 PTS | Turf Moor · Burnley, England |
| 6 | Sat Sep 27 | atMan City | L1-5 | 1-1-4 | 4 PTS | Etihad Stadium · Manchester, England |
| 7 | Sun Oct 5 | atA Villa | L1-2 | 1-1-5 | 4 PTS | Villa Park · Birmingham, England |
| 8 | Sat Oct 18 | vsLeeds | W2-0 | 2-1-5 | 7 PTS | Turf Moor · Burnley, England |
| 9 | Sun Oct 26 | atWolves | W3-2 | 3-1-5 | 10 PTS | Molineux Stadium · Wolverhampton, England |
| 10 | Sat Nov 1 | vsArsenal | L0-2 | 3-1-6 | 10 PTS | Turf Moor · Burnley, England |
| 11 | Sat Nov 8 | atWest Ham | L2-3 | 3-1-7 | 10 PTS | London Stadium · London, England |
| 12 | Sat Nov 22 | vsChelsea | L0-2 | 3-1-8 | 10 PTS | Turf Moor · Burnley, England |
| 13 | Sat Nov 29 | atBrentford | L1-3 | 3-1-9 | 10 PTS | Gtech Community Stadium · Brentford, England |
| 14 | Wed Dec 3 | vsC Palace | L0-1 | 3-1-10 | 10 PTS | Turf Moor · Burnley, England |
| 15 | Sat Dec 6 | atNewcastle | L1-2 | 3-1-11 | 10 PTS | St. James' Park · Newcastle, England |
| 16 | Sat Dec 13 | vsFulham | L2-3 | 3-1-12 | 10 PTS | Turf Moor · Burnley, England |
| 17 | Sat Dec 20 | atB'mouth | D1-1 | 3-2-12 | 11 PTS | Vitality Stadium · Bournemouth, England |
| 18 | Sat Dec 27 | vsEverton | D0-0 | 3-3-12 | 12 PTS | Turf Moor · Burnley, England |
| 19 | Tue Dec 30 | vsNewcastle | L1-3 | 3-3-13 | 12 PTS | Turf Moor · Burnley, England |
| 20 | Sat Jan 3 | atBrighton | L0-2 | 3-3-14 | 12 PTS | American Express Stadium · Brighton, England |
| 21 | Wed Jan 7 | vsMan Utd | D2-2 | 3-4-14 | 13 PTS | Turf Moor · Burnley, England |
| 22 | Sat Jan 17 | atLiverpool | D1-1 | 3-5-14 | 14 PTS | Anfield · Liverpool, England |
| 23 | Sat Jan 24 | vsSpurs | D2-2 | 3-6-14 | 15 PTS | Turf Moor · Burnley, England |
| 24 | Mon Feb 2 | atSunderland | L0-3 | 3-6-15 | 15 PTS | Stadium of Light · Sunderland, England |
| 25 | Sat Feb 7 | vsWest Ham | L0-2 | 3-6-16 | 15 PTS | Turf Moor · Burnley, England |
| 26 | Wed Feb 11 | atC Palace | W3-2 | 4-6-16 | 18 PTS | Selhurst Park · London, England |
| 27 | Sat Feb 21 | atChelsea | D1-1 | 4-7-16 | 19 PTS | Stamford Bridge · London, England |
| 28 | Sat Feb 28 | vsBrentford | L3-4 | 4-7-17 | 19 PTS | Turf Moor · Burnley, England |
