| 1 | Thu Mar 27 | vs Red Sox | L2-5 | 0-1 | .000 | Globe Life Field · Arlington, TX |
| 2 | Fri Mar 28 | vs Red Sox | W4-1 | 1-1 | .500 | Globe Life Field · Arlington, TX |
| 3 | Sat Mar 29 | vs Red Sox | W4-3 | 2-1 | .667 | Globe Life Field · Arlington, TX |
| 4 | Sun Mar 30 | vs Red Sox | W3-2 | 3-1 | .750 | Globe Life Field · Arlington, TX |
| 5 | Mon Mar 31 | at Reds | L3-14 | 3-2 | .600 | Great American Ball Park · Cincinnati, OH |
| 6 | Tue Apr 1 | at Reds | W1-0 | 4-2 | .667 | Great American Ball Park · Cincinnati, OH |
| 7 | Wed Apr 2 | at Reds | W1-0 | 5-2 | .714 | Great American Ball Park · Cincinnati, OH |
| 8 | Fri Apr 4 | vs Rays | W5-2 | 6-2 | .750 | Globe Life Field · Arlington, TX |
| 9 | Sat Apr 5 | vs Rays | W6-4 | 7-2 | .778 | Globe Life Field · Arlington, TX |
| 10 | Sun Apr 6 | vs Rays | W4-3 | 8-2 | .800 | Globe Life Field · Arlington, TX |
| 11 | Mon Apr 7 | at Cubs | L0-7 | 8-3 | .727 | Wrigley Field · Chicago, IL |
| 12 | Tue Apr 8 | at Cubs | L6-10 | 8-4 | .667 | Wrigley Field · Chicago, IL |
| 13 | Wed Apr 9 | at Cubs | W6-2 | 9-4 | .692 | Wrigley Field · Chicago, IL |
| 14 | Fri Apr 11 | at Mariners | L3-5 | 9-5 | .643 | T-Mobile Park · Seattle, WA |
| 15 | Sat Apr 12 | at Mariners | L2-9 | 9-6 | .600 | T-Mobile Park · Seattle, WA |
| 16 | Sun Apr 13 | at Mariners | L1-3 | 9-7 | .563 | T-Mobile Park · Seattle, WA |
| 17 | Tue Apr 15 | vs Angels | W4-0 | 10-7 | .588 | Globe Life Field · Arlington, TX |
| 18 | Wed Apr 16 | vs Angels | W3-1 | 11-7 | .611 | Globe Life Field · Arlington, TX |
| 19 | Thu Apr 17 | vs Angels | W5-3 | 12-7 | .632 | Globe Life Field · Arlington, TX |
| 20 | Fri Apr 18 | vs Dodgers | L0-3 | 12-8 | .600 | Globe Life Field · Arlington, TX |
| 21 | Sat Apr 19 | vs Dodgers | W4-3 | 13-8 | .619 | Globe Life Field · Arlington, TX |
| 22 | Sun Apr 20 | vs Dodgers | L0-1 | 13-9 | .591 | Globe Life Field · Arlington, TX |
| 23 | Tue Apr 22 | at Athletics | W8-5 | 14-9 | .609 | Sutter Health Park · West Sacramento, CA |
| 24 | Wed Apr 23 | at Athletics | L2-5 | 14-10 | .583 | Sutter Health Park · West Sacramento, CA |
| 25 | Thu Apr 24 | at Athletics | L3-4 | 14-11 | .560 | Sutter Health Park · West Sacramento, CA |
| 26 | Fri Apr 25 | at Giants | W2-0 | 15-11 | .577 | Oracle Park · San Francisco, CA |
| 27 | Sat Apr 26 | at Giants | L2-3 | 15-12 | .556 | Oracle Park · San Francisco, CA |
| 28 | Sun Apr 27 | at Giants | L2-3 | 15-13 | .536 | Oracle Park · San Francisco, CA |
| 29 | Mon Apr 28 | vs Athletics | L1-2 | 15-14 | .517 | Globe Life Field · Arlington, TX |
| 30 | Tue Apr 29 | vs Athletics | W15-2 | 16-14 | .533 | Globe Life Field · Arlington, TX |
| 31 | Wed Apr 30 | vs Athletics | L1-7 | 16-15 | .516 | Globe Life Field · Arlington, TX |
| 32 | Thu May 1 | vs Athletics | L0-3 | 16-16 | .500 | Globe Life Field · Arlington, TX |
| 33 | Fri May 2 | vs Mariners | L1-13 | 16-17 | .485 | Globe Life Field · Arlington, TX |
| 34 | Sat May 3 | vs Mariners | L1-2 | 16-18 | .471 | Globe Life Field · Arlington, TX |
| 35 | Sun May 4 | vs Mariners | W8-1 | 17-18 | .486 | Globe Life Field · Arlington, TX |
| 36 | Tue May 6 | at Red Sox | W6-1 | 18-18 | .500 | Fenway Park · Boston, MA |
| 37 | Wed May 7 | at Red Sox | L4-6 | 18-19 | .486 | Fenway Park · Boston, MA |
| 38 | Thu May 8 | at Red Sox | L0-5 | 18-20 | .474 | Fenway Park · Boston, MA |
| 39 | Fri May 9 | at Tigers | L1-2 | 18-21 | .462 | Comerica Park · Detroit, MI |
| 40 | Sat May 10 | at Tigers | W10-3 | 19-21 | .475 | Comerica Park · Detroit, MI |
| 41 | Sun May 11 | at Tigers | W6-1 | 20-21 | .488 | Comerica Park · Detroit, MI |
| 42 | Mon May 12 | vs Rockies | W2-1 | 21-21 | .500 | Globe Life Field · Arlington, TX |
| 43 | Tue May 13 | vs Rockies | W4-1 | 22-21 | .512 | Globe Life Field · Arlington, TX |
| 44 | Wed May 14 | vs Rockies | W8-3 | 23-21 | .523 | Globe Life Field · Arlington, TX |
| 45 | Thu May 15 | vs Astros | W1-0 | 24-21 | .533 | Globe Life Field · Arlington, TX |
| 46 | Fri May 16 | vs Astros | L3-6 | 24-22 | .522 | Globe Life Field · Arlington, TX |
| 47 | Sat May 17 | vs Astros | W5-1 | 25-22 | .532 | Globe Life Field · Arlington, TX |
| 48 | Sun May 18 | vs Astros | L3-4 | 25-23 | .521 | Globe Life Field · Arlington, TX |
| 49 | Tue May 20 | at Yankees | L2-5 | 25-24 | .510 | Yankee Stadium · The Bronx, NY |
| 50 | Wed May 21 | at Yankees | L3-4 | 25-25 | .500 | Yankee Stadium · The Bronx, NY |
| 51 | Thu May 22 | at Yankees | L0-1 | 25-26 | .490 | Yankee Stadium · The Bronx, NY |
| 52 | Fri May 23 | at White Sox | L1-4 | 25-27 | .481 | Guaranteed Rate Field · Chicago, IL |
| 53 | Sat May 24 | at White Sox | L5-10 | 25-28 | .472 | Guaranteed Rate Field · Chicago, IL |
| 54 | Sun May 25 | at White Sox | W5-4 | 26-28 | .481 | Guaranteed Rate Field · Chicago, IL |
| 55 | Mon May 26 | vs Blue Jays | L1-2 | 26-29 | .473 | Globe Life Field · Arlington, TX |
| 56 | Tue May 27 | vs Blue Jays | W2-0 | 27-29 | .482 | Globe Life Field · Arlington, TX |
| 57 | Wed May 28 | vs Blue Jays | L0-2 | 27-30 | .474 | Globe Life Field · Arlington, TX |
| 58 | Fri May 30 | vs Cardinals | W11-1 | 28-30 | .483 | Globe Life Field · Arlington, TX |
| 59 | Sat May 31 | vs Cardinals | L0-2 | 28-31 | .475 | Globe Life Field · Arlington, TX |
| 60 | Sun Jun 1 | vs Cardinals | W8-1 | 29-31 | .483 | Globe Life Field · Arlington, TX |
| 61 | Tue Jun 3 | at Rays | L1-5 | 29-32 | .475 | Tropicana Field · St. Petersburg, FL |
| 62 | Wed Jun 4 | at Rays | L4-5 | 29-33 | .468 | Tropicana Field · St. Petersburg, FL |
| 63 | Thu Jun 5 | at Rays | L3-4 | 29-34 | .460 | Tropicana Field · St. Petersburg, FL |
| 64 | Fri Jun 6 | at Nationals | L0-2 | 29-35 | .453 | Nationals Park · Washington, D.C. |
| 65 | Sat Jun 7 | at Nationals | W5-0 | 30-35 | .462 | Nationals Park · Washington, D.C. |
| 66 | Sun Jun 8 | at Nationals | W4-2 | 31-35 | .470 | Nationals Park · Washington, D.C. |
| 67 | Tue Jun 10 | at Twins | W16-4 | 32-35 | .478 | Target Field · Minneapolis, MN |
| 68 | Wed Jun 11 | at Twins | L2-6 | 32-36 | .471 | Target Field · Minneapolis, MN |
| 69 | Thu Jun 12 | at Twins | W16-3 | 33-36 | .478 | Target Field · Minneapolis, MN |
| 70 | Fri Jun 13 | vs White Sox | W3-1 | 34-36 | .486 | Globe Life Field · Arlington, TX |
| 71 | Sat Jun 14 | vs White Sox | W5-4 (11) | 35-36 | .493 | Globe Life Field · Arlington, TX |
| 72 | Sun Jun 15 | vs White Sox | W2-1 | 36-36 | .500 | Globe Life Field · Arlington, TX |
| 73 | Tue Jun 17 | vs Royals | L1-6 | 36-37 | .493 | Globe Life Field · Arlington, TX |
| 74 | Wed Jun 18 | vs Royals | L3-6 | 36-38 | .486 | Globe Life Field · Arlington, TX |
| 75 | Thu Jun 19 | vs Royals | L1-4 | 36-39 | .480 | Globe Life Field · Arlington, TX |
| 76 | Fri Jun 20 | at Pirates | W6-2 | 37-39 | .487 | PNC Park · Pittsburgh, PA |
| 77 | Sat Jun 21 | at Pirates | W3-2 | 38-39 | .494 | PNC Park · Pittsburgh, PA |
| 78 | Sun Jun 22 | at Pirates | L3-8 | 38-40 | .487 | PNC Park · Pittsburgh, PA |
| 79 | Mon Jun 23 | at Orioles | L0-6 | 38-41 | .481 | Camden Yards · Baltimore, MD |
| 80 | Tue Jun 24 | at Orioles | W6-5 (10) | 39-41 | .487 | Camden Yards · Baltimore, MD |
| 81 | Wed Jun 25 | at Orioles | W7-0 | 40-41 | .494 | Camden Yards · Baltimore, MD |
| 82 | Fri Jun 27 | vs Mariners | L6-7 (12) | 40-42 | .488 | Globe Life Field · Arlington, TX |
| 83 | Sat Jun 28 | vs Mariners | W3-2 (10) | 41-42 | .494 | Globe Life Field · Arlington, TX |
| 84 | Sun Jun 29 | vs Mariners | L4-6 (12) | 41-43 | .488 | Globe Life Field · Arlington, TX |
| 85 | Mon Jun 30 | vs Orioles | L6-10 (11) | 41-44 | .482 | Globe Life Field · Arlington, TX |
| 86 | Tue Jul 1 | vs Orioles | W10-2 | 42-44 | .488 | Globe Life Field · Arlington, TX |
| 87 | Wed Jul 2 | vs Orioles | W6-0 | 43-44 | .494 | Globe Life Field · Arlington, TX |
| 88 | Fri Jul 4 | at Padres | L2-3 (10) | 43-45 | .489 | Petco Park · San Diego, CA |
| 89 | Sat Jul 5 | at Padres | W7-4 | 44-45 | .494 | Petco Park · San Diego, CA |
| 90 | Sun Jul 6 | at Padres | L1-4 | 44-46 | .489 | Petco Park · San Diego, CA |
| 91 | Mon Jul 7 | at Angels | L5-6 | 44-47 | .484 | Angel Stadium · Anaheim, CA |
| 92 | Tue Jul 8 | at Angels | W13-1 | 45-47 | .489 | Angel Stadium · Anaheim, CA |
| 93 | Wed Jul 9 | at Angels | L8-11 | 45-48 | .484 | Angel Stadium · Anaheim, CA |
| 94 | Thu Jul 10 | at Angels | W11-4 | 46-48 | .489 | Angel Stadium · Anaheim, CA |
| 95 | Fri Jul 11 | at Astros | W7-3 | 47-48 | .495 | Minute Maid Park · Houston, TX |
| 96 | Sat Jul 12 | at Astros | L4-5 (11) | 47-49 | .490 | Minute Maid Park · Houston, TX |
| 97 | Sun Jul 13 | at Astros | W5-1 | 48-49 | .495 | Minute Maid Park · Houston, TX |
| 98 | Fri Jul 18 | vs Tigers | W2-0 | 49-49 | .500 | Globe Life Field · Arlington, TX |
| 99 | Sat Jul 19 | vs Tigers | W4-1 | 50-49 | .505 | Globe Life Field · Arlington, TX |
| 100 | Sun Jul 20 | vs Tigers | L1-2 | 50-50 | .500 | Globe Life Field · Arlington, TX |
| 101 | Mon Jul 21 | vs Athletics | W7-2 | 51-50 | .505 | Globe Life Field · Arlington, TX |
| 102 | Tue Jul 22 | vs Athletics | W6-2 | 52-50 | .510 | Globe Life Field · Arlington, TX |
| 103 | Wed Jul 23 | vs Athletics | W2-1 | 53-50 | .515 | Globe Life Field · Arlington, TX |
| 104 | Fri Jul 25 | vs Braves | W8-3 | 54-50 | .519 | Globe Life Field · Arlington, TX |
| 105 | Sat Jul 26 | vs Braves | W6-5 (10) | 55-50 | .524 | Globe Life Field · Arlington, TX |
| 106 | Sun Jul 27 | vs Braves | W8-1 | 56-50 | .528 | Globe Life Field · Arlington, TX |
| 107 | Mon Jul 28 | at Angels | L4-6 | 56-51 | .523 | Angel Stadium · Anaheim, CA |
| 108 | Tue Jul 29 | at Angels | L5-8 | 56-52 | .519 | Angel Stadium · Anaheim, CA |
| 109 | Wed Jul 30 | at Angels | W6-3 | 57-52 | .523 | Angel Stadium · Anaheim, CA |
| 110 | Thu Jul 31 | at Mariners | L0-6 | 57-53 | .518 | T-Mobile Park · Seattle, WA |
| 111 | Fri Aug 1 | at Mariners | L3-4 | 57-54 | .514 | T-Mobile Park · Seattle, WA |
| 112 | Sat Aug 2 | at Mariners | W6-4 (11) | 58-54 | .518 | T-Mobile Park · Seattle, WA |
| 113 | Sun Aug 3 | at Mariners | L4-5 | 58-55 | .513 | T-Mobile Park · Seattle, WA |
| 114 | Mon Aug 4 | vs Yankees | W8-5 (10) | 59-55 | .518 | Globe Life Field · Arlington, TX |
| 115 | Tue Aug 5 | vs Yankees | W2-0 | 60-55 | .522 | Globe Life Field · Arlington, TX |
| 116 | Wed Aug 6 | vs Yankees | L2-3 | 60-56 | .517 | Globe Life Field · Arlington, TX |
| 117 | Fri Aug 8 | vs Phillies | L1-9 | 60-57 | .513 | Globe Life Field · Arlington, TX |
| 118 | Sat Aug 9 | vs Phillies | L2-3 | 60-58 | .508 | Globe Life Field · Arlington, TX |
| 119 | Sun Aug 10 | vs Phillies | L2-4 | 60-59 | .504 | Globe Life Field · Arlington, TX |
| 120 | Mon Aug 11 | vs D-backs | W7-6 (10) | 61-59 | .508 | Globe Life Field · Arlington, TX |
| 121 | Tue Aug 12 | vs D-backs | L2-3 | 61-60 | .504 | Globe Life Field · Arlington, TX |
| 122 | Wed Aug 13 | vs D-backs | L4-6 | 61-61 | .500 | Globe Life Field · Arlington, TX |
| 123 | Fri Aug 15 | at Blue Jays | L5-6 | 61-62 | .496 | Rogers Centre · Toronto, ON |
| 124 | Sat Aug 16 | at Blue Jays | L2-14 | 61-63 | .492 | Rogers Centre · Toronto, ON |
| 125 | Sun Aug 17 | at Blue Jays | W10-4 | 62-63 | .496 | Rogers Centre · Toronto, ON |
| 126 | Mon Aug 18 | at Royals | L3-4 | 62-64 | .492 | Kauffman Stadium · Kansas City, MO |
| 127 | Tue Aug 19 | at Royals | L2-5 | 62-65 | .488 | Kauffman Stadium · Kansas City, MO |
| 128 | Wed Aug 20 | at Royals | W6-3 | 63-65 | .492 | Kauffman Stadium · Kansas City, MO |
| 129 | Thu Aug 21 | at Royals | L4-6 | 63-66 | .488 | Kauffman Stadium · Kansas City, MO |
| 130 | Fri Aug 22 | vs Guardians | W4-3 | 64-66 | .492 | Globe Life Field · Arlington, TX |
| 131 | Sat Aug 23 | vs Guardians | W10-0 | 65-66 | .496 | Globe Life Field · Arlington, TX |
| 132 | Sun Aug 24 | vs Guardians | W5-0 | 66-66 | .500 | Globe Life Field · Arlington, TX |
| 133 | Mon Aug 25 | vs Angels | L0-4 | 66-67 | .496 | Globe Life Field · Arlington, TX |
| 134 | Tue Aug 26 | vs Angels | W7-3 | 67-67 | .500 | Globe Life Field · Arlington, TX |
| 135 | Wed Aug 27 | vs Angels | W20-3 | 68-67 | .504 | Globe Life Field · Arlington, TX |
| 136 | Fri Aug 29 | at Athletics | W5-2 | 69-67 | .507 | Sutter Health Park · West Sacramento, CA |
| 137 | Sat Aug 30 | at Athletics | W9-3 | 70-67 | .511 | Sutter Health Park · West Sacramento, CA |
| 138 | Sun Aug 31 | at Athletics | W9-6 | 71-67 | .514 | Sutter Health Park · West Sacramento, CA |
| 139 | Mon Sep 1 | at D-backs | W7-5 (10) | 72-67 | .518 | Chase Field · Phoenix, AZ |
| 140 | Tue Sep 2 | at D-backs | L3-5 | 72-68 | .514 | Chase Field · Phoenix, AZ |
| 141 | Wed Sep 3 | at D-backs | L0-2 | 72-69 | .511 | Chase Field · Phoenix, AZ |
| 142 | Fri Sep 5 | vs Astros | W4-3 (12) | 73-69 | .514 | Globe Life Field · Arlington, TX |
| 143 | Sat Sep 6 | vs Astros | L0-11 | 73-70 | .510 | Globe Life Field · Arlington, TX |
| 144 | Sun Sep 7 | vs Astros | W4-2 | 74-70 | .514 | Globe Life Field · Arlington, TX |
| 145 | Mon Sep 8 | vs Brewers | W5-0 | 75-70 | .517 | Globe Life Field · Arlington, TX |
| 146 | Tue Sep 9 | vs Brewers | W5-4 | 76-70 | .521 | Globe Life Field · Arlington, TX |
| 147 | Wed Sep 10 | vs Brewers | W6-3 | 77-70 | .524 | Globe Life Field · Arlington, TX |
| 148 | Fri Sep 12 | at Mets | W8-3 | 78-70 | .527 | Citi Field · Queens, NY |
| 149 | Sat Sep 13 | at Mets | W3-2 | 79-70 | .530 | Citi Field · Queens, NY |
| 150 | Sun Sep 14 | at Mets | L2-5 (10) | 79-71 | .527 | Citi Field · Queens, NY |
| 151 | Mon Sep 15 | at Astros | L3-6 | 79-72 | .523 | Minute Maid Park · Houston, TX |
| 152 | Tue Sep 16 | at Astros | L5-6 | 79-73 | .520 | Minute Maid Park · Houston, TX |
| 153 | Wed Sep 17 | at Astros | L2-5 | 79-74 | .516 | Minute Maid Park · Houston, TX |
| 154 | Fri Sep 19 | vs Marlins | L4-6 (12) | 79-75 | .513 | Globe Life Field · Arlington, TX |
| 155 | Sat Sep 20 | vs Marlins | L3-4 | 79-76 | .510 | Globe Life Field · Arlington, TX |
| 156 | Sun Sep 21 | vs Marlins | L2-4 | 79-77 | .506 | Globe Life Field · Arlington, TX |
| 157 | Tue Sep 23 | vs Twins | L1-4 | 79-78 | .503 | Globe Life Field · Arlington, TX |
| 158 | Wed Sep 24 | vs Twins | W4-2 | 80-78 | .506 | Globe Life Field · Arlington, TX |
| 159 | Thu Sep 25 | vs Twins | L0-4 | 80-79 | .503 | Globe Life Field · Arlington, TX |
| 160 | Fri Sep 26 | at Guardians | W7-3 | 81-79 | .506 | Progressive Field · Cleveland, OH |
| 161 | Sat Sep 27 | at Guardians | L2-3 | 81-80 | .503 | Progressive Field · Cleveland, OH |
| 162 | Sun Sep 28 | at Guardians | L8-9 (10) | 81-81 | .500 | Progressive Field · Cleveland, OH |