| 1 | Sat Nov 9 | at Brown | L68-75 | 0-1 | .000 | - | | Pizzitola Sports Center · Providence, RI |
| 2 | Wed Nov 13 | at Albany | L57-83 | 0-2 | .000 | - | | SEFCU Arena · Albany, NY |
| 3 | Sat Nov 16 | vs Bucknell | W83-81 | 1-2 | .333 | - | | Koessler Athletic Center · Buffalo, NY |
| 4 | Sat Nov 23 | vs St Bonaventure | W61-57 | 2-2 | .500 | - | | Koessler Athletic Center · Buffalo, NY |
| 5 | Tue Nov 26 | at UIC | W94-64 | 3-2 | .600 | - | | Credit Union 1 Arena · Chicago, IL |
| 6 | Sun Dec 1 | at Mercer | W76-66 | 4-2 | .667 | - | | Hawkins Arena · Macon, GA |
| 7 | Mon Dec 2 | vs Hofstra | L57-64 | 4-3 | .571 | - | | Koessler Athletic Center · Buffalo, NY |
| 8 | Wed Dec 4 | at FAU | L59-62 | 4-4 | .500 | - | | FAU Arena · Boca Raton, FL |
| 9 | Sat Dec 14 | vs Holy Cross | W80-72 | 5-4 | .556 | - | | Koessler Athletic Center · Buffalo, NY |
| 10 | Wed Dec 18 | at Buffalo | L73-82 | 5-5 | .500 | - | | Alumni Arena · Buffalo, NY |
| 11 | Mon Dec 23 | at Siena | L72-73 | 5-6 | .455 | - | | MVP Arena · Albany, NY |
| 12 | Mon Dec 30 | at Pitt | L79-87 | 5-7 | .417 | - | | Petersen Events Center · Pittsburgh, PA |
| 13 | Fri Jan 3 | vs Manhattan | L67-71 | 5-8 | .385 | - | | Koessler Athletic Center · Buffalo, NY |
| 14 | Sun Jan 5 | vs Fairfield | L42-46 | 5-9 | .357 | - | | Koessler Athletic Center · Buffalo, NY |
| 15 | Fri Jan 10 | at Monmouth | L65-84 | 5-10 | .333 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 16 | Sun Jan 12 | at Saint Peter's | W72-68 | 6-10 | .375 | - | | Yanitelli Center · Jersey City, NJ |
| 17 | Fri Jan 17 | vsSiena | W73-63 | 7-10 | .412 | - | | Koessler Athletic Center · Buffalo, NY |
| 18 | Sun Jan 19 | vs Rider | W95-86 | 8-10 | .444 | - | | Koessler Athletic Center · Buffalo, NY |
| 19 | Fri Jan 24 | at Iona | L66-69 | 8-11 | .421 | - | | Hynes Athletics Center · New Rochelle, NY |
| 20 | Sun Jan 26 | atFairfield | L55-63 | 8-12 | .400 | - | | Leo D. Mahoney Arena · Fairfield, CT |
| 21 | Fri Jan 31 | vs Quinnipiac | L73-90 | 8-13 | .381 | - | | Koessler Athletic Center · Buffalo, NY |
| 22 | Sun Feb 2 | vs Marist | W66-65 | 9-13 | .409 | - | | Koessler Athletic Center · Buffalo, NY |
| 23 | Fri Feb 7 | atRider | L60-61 | 9-14 | .391 | - | | Alumni Gymnasium (Rider) · Lawrenceville, NJ |
| 24 | Wed Feb 12 | at Niagara | L66-69 | 9-15 | .375 | - | | Gallagher Center · Niagara Falls, NY |
| 25 | Fri Feb 14 | vsMonmouth | L71-85 | 9-16 | .360 | - | | Koessler Athletic Center · Buffalo, NY |
| 26 | Fri Feb 21 | atQuinnipiac | L64-66 | 9-17 | .346 | - | ESPNU | M&T Bank Arena · Hamden, CT |
| 27 | Sun Feb 23 | atManhattan | W57-56 | 10-17 | .370 | - | | Draddy Gymnasium · Riverdale, NY |
| 28 | Thu Feb 27 | vsIona | L65-86 | 10-18 | .357 | - | | Koessler Athletic Center · Buffalo, NY |
| 29 | Sat Feb 29 | vsSaint Peter's | L68-69 | 10-19 | .345 | - | | Koessler Athletic Center · Buffalo, NY |
| 30 | Wed Mar 4 | atMarist | W85-69 | 11-19 | .367 | - | | McCann Arena · Poughkeepsie, NY |
| 31 | Fri Mar 6 | vsNiagara | W67-63 | 12-19 | .387 | - | | Koessler Athletic Center · Buffalo, NY |
| 32 | Tue Mar 10 | atIona | L60-70 | 12-20 | .375 | - | | Hynes Athletics Center · New Rochelle, NY |
