| 1 | Mon Nov 3 | at Dayton | TBD | 23-11 | .676 | - | ESPN+ | UD Arena · Dayton, OH |
| 2 | Thu Nov 6 | vsTBD | TBD | 0-0 | .000 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 3 | Sat Nov 8 | atSt Bonaventure | TBD | 22-12 | .647 | - | ESPN+ | Reilly Center · Saint Bonaventure, NY |
| 4 | Wed Nov 12 | vsMercyhurst | TBD | 15-16 | .484 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 5 | Mon Nov 17 | atHigh Point | 7:00 PM | 29-6 | .829 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 6 | Fri Nov 21 | vsMD-Eastern | 7:00 PM | 6-25 | .194 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 7 | Sun Nov 23 | vsBinghamton | 1:00 PM | 15-17 | .469 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 8 | Sat Nov 29 | vsBuffalo | 6:00 PM | 9-22 | .290 | - | ESPN+ | Koessler Athletic Center · Buffalo, NY |
| 9 | Fri Dec 5 | atSaint Peter's | 7:00 PM | 12-16 | .429 | - | | Yanitelli Center · Jersey City, NJ |
| 10 | Sun Dec 7 | atSiena | TBD | 14-18 | .438 | - | | MVP Arena · Albany, NY |
| 11 | Sat Dec 13 | atMaine | TBD | 20-14 | .588 | - | | Cross Insurance Center · Bangor, ME |
| 12 | Tue Dec 16 | atRhode Island | TBD | 18-13 | .581 | - | | Ryan Center · Kingston, RI |
| 13 | Mon Dec 22 | atDuquesne | 7:00 PM | 13-19 | .406 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 14 | Fri Jan 2 | vsFairfield | TBD | 12-20 | .375 | - | | Koessler Athletic Center · Buffalo, NY |
| 15 | Sun Jan 4 | vsSacred Heart | TBD | 15-18 | .455 | - | | Koessler Athletic Center · Buffalo, NY |
| 16 | Fri Jan 9 | atManhattan | TBD | 17-14 | .548 | - | | Draddy Gymnasium · Riverdale, NY |
| 17 | Sun Jan 11 | atIona | TBD | 17-17 | .500 | - | | Hynes Athletics Center · New Rochelle, NY |
| 18 | Wed Jan 14 | vsNiagara | TBD | 11-20 | .355 | - | | Koessler Athletic Center · Buffalo, NY |
| 19 | Sat Jan 17 | vsMount St Mary | TBD | 23-13 | .639 | - | | Koessler Athletic Center · Buffalo, NY |
| 20 | Thu Jan 22 | atSacred Heart | 7:00 PM | 15-18 | .455 | - | | William H. Pitt Center · Fairfield, CT |
| 21 | Sat Jan 24 | atFairfield | TBD | 12-20 | .375 | - | | Leo D. Mahoney Arena · Fairfield, CT |
| 22 | Fri Jan 30 | vsMarist | 7:00 PM | 20-10 | .667 | - | | Koessler Athletic Center · Buffalo, NY |
| 23 | Sun Feb 1 | vsSiena | TBD | 14-18 | .438 | - | | Koessler Athletic Center · Buffalo, NY |
| 24 | Tue Feb 3 | atNiagara | TBD | 11-20 | .355 | - | | Gallagher Center · Niagara Falls, NY |
| 25 | Thu Feb 5 | atQuinnipiac | 7:00 PM | 20-13 | .606 | - | | M&T Bank Arena · Hamden, CT |
| 26 | Fri Feb 13 | vsIona | TBD | 17-17 | .500 | - | | Koessler Athletic Center · Buffalo, NY |
| 27 | Sun Feb 15 | vsManhattan | TBD | 17-14 | .548 | - | | Koessler Athletic Center · Buffalo, NY |
| 28 | Fri Feb 20 | atRider | TBD | 14-19 | .424 | - | | Alumni Gymnasium (Rider) · Lawrenceville, NJ |
| 29 | Sun Feb 22 | atMount St Mary | 2:00 PM | 23-13 | .639 | - | | Knott Arena · Emmitsburg, MD |
| 30 | Fri Feb 27 | vsMerrimack | TBD | 18-15 | .545 | - | | Koessler Athletic Center · Buffalo, NY |
| 31 | Sun Mar 1 | vsQuinnipiac | TBD | 20-13 | .606 | - | | Koessler Athletic Center · Buffalo, NY |
