| 1 | Wed Nov 8 | at Syracuse | L77-89 | 0-1 | .000 | - | | JMA Wireless Dome · Syracuse, NY |
| 2 | Sat Nov 11 | at St Bonaventure | W70-67 | 1-1 | .500 | - | | Reilly Center · Saint Bonaventure, NY |
| 3 | Wed Nov 15 | at Cleveland St | L61-71 | 1-2 | .333 | - | | Wolstein Center · Cleveland, OH |
| 4 | Mon Nov 20 | vs TBD | W109-69 | 2-2 | .500 | - | | Koessler Athletic Center · Buffalo, NY |
| 5 | Fri Nov 24 | at Wofford | W76-67 | 3-2 | .600 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 6 | Sat Nov 25 | vs Western KY | W85-77 | 4-2 | .667 | - | | Koessler Athletic Center · Buffalo, NY |
| 7 | Sun Nov 26 | at Bowling Green | L73-77 | 4-3 | .571 | - | | Stroh Center · Bowling Green, OH |
| 8 | Fri Dec 1 | vs Quinnipiac | W93-73 | 5-3 | .625 | - | | Koessler Athletic Center · Buffalo, NY |
| 9 | Sun Dec 3 | vs Saint Peter's | L52-54 | 5-4 | .556 | - | | Koessler Athletic Center · Buffalo, NY |
| 10 | Wed Dec 6 | vs Robert Morris | W87-80 | 6-4 | .600 | - | | Koessler Athletic Center · Buffalo, NY |
| 11 | Sat Dec 9 | at Pitt | L71-82 | 6-5 | .545 | - | | Petersen Events Center · Pittsburgh, PA |
| 12 | Fri Dec 22 | at High Point | L70-78 | 6-6 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 13 | Fri Jan 5 | at Mount St Mary | L69-74 | 6-7 | .462 | - | | Knott Arena · Emmitsburg, MD |
| 14 | Sun Jan 7 | at Rider | L76-79 (OT) | 6-8 | .429 | - | | Alumni Gymnasium (Rider) · Lawrenceville, NJ |
| 15 | Fri Jan 12 | vs Siena | W67-63 | 7-8 | .467 | - | | Koessler Athletic Center · Buffalo, NY |
| 16 | Mon Jan 15 | vs Fairfield | L63-88 | 7-9 | .438 | - | | Koessler Athletic Center · Buffalo, NY |
| 17 | Fri Jan 19 | at Iona | L58-70 | 7-10 | .412 | - | | Hynes Athletics Center · New Rochelle, NY |
| 18 | Sun Jan 21 | atSaint Peter's | L59-70 | 7-11 | .389 | - | | Yanitelli Center · Jersey City, NJ |
| 19 | Fri Jan 26 | vs Manhattan | W82-70 | 8-11 | .421 | - | | Koessler Athletic Center · Buffalo, NY |
| 20 | Sun Jan 28 | vs Marist | L71-80 | 8-12 | .400 | - | | Koessler Athletic Center · Buffalo, NY |
| 21 | Sun Feb 4 | atQuinnipiac | L63-88 | 8-13 | .381 | - | | M&T Bank Arena · Hamden, CT |
| 22 | Tue Feb 6 | at Niagara | L64-69 | 8-14 | .364 | - | | Gallagher Center · Niagara Falls, NY |
| 23 | Sat Feb 10 | vsIona | W73-69 | 9-14 | .391 | - | | Koessler Athletic Center · Buffalo, NY |
| 24 | Fri Feb 16 | atMarist | L55-78 | 9-15 | .375 | - | | McCann Arena · Poughkeepsie, NY |
| 25 | Sun Feb 18 | atSiena | W73-64 | 10-15 | .400 | - | | MVP Arena · Albany, NY |
| 26 | Fri Feb 23 | vsNiagara | W69-59 | 11-15 | .423 | - | | Koessler Athletic Center · Buffalo, NY |
| 27 | Fri Mar 1 | vsMount St Mary | W61-56 | 12-15 | .444 | - | | Koessler Athletic Center · Buffalo, NY |
| 28 | Sun Mar 3 | vsRider | L61-65 | 12-16 | .429 | - | | Koessler Athletic Center · Buffalo, NY |
| 29 | Thu Mar 7 | atFairfield | L62-74 | 12-17 | .414 | - | ESPNU | Leo D. Mahoney Arena · Fairfield, CT |
| 30 | Sat Mar 9 | atManhattan | W73-70 (OT) | 13-17 | .433 | - | | Draddy Gymnasium · Riverdale, NY |
| 31 | Tue Mar 12 | atMount St Mary | W77-61 | 14-17 | .452 | - | | Knott Arena · Emmitsburg, MD |
| 32 | Wed Mar 13 | atQuinnipiac | L52-76 | 14-18 | .438 | - | | M&T Bank Arena · Hamden, CT |
