| 1 | Wed Dec 2 | vs Army | W76-69 | 1-0 | 1.000 | - | ESPN2 | O'Connell Center · Gainesville, FL |
| 2 | Thu Dec 3 | atBoston College | W90-70 | 2-0 | 1.000 | - | ESPN | Silvio O. Conte Forum · Chestnut Hill, MA |
| 3 | Sun Dec 6 | vsStetson | W86-40 | 3-0 | 1.000 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 4 | Sat Dec 12 | at20Florida St | L71-83 | 3-1 | .750 | - | ESPNU | Donald L. Tucker Center · Tallahassee, FL |
| 8 | Wed Dec 30 | atVanderbilt | W91-72 | 4-1 | .800 | - | ESPN2 | Memorial Gymnasium (TN) · Nashville, TN |
| 9 | Sat Jan 2 | vsLSU | W83-79 | 5-1 | .833 | - | CBS | O'Connell Center · Gainesville, FL |
| 10 | Tue Jan 5 | atAlabama | L71-86 | 5-2 | .714 | - | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 11 | Sat Jan 9 | vsKentucky | L58-76 | 5-3 | .625 | - | ESPN | O'Connell Center · Gainesville, FL |
| 12 | Tue Jan 12 | vsOle Miss | W72-63 | 6-3 | .667 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 13 | Sat Jan 16 | atMississippi St | L69-72 | 6-4 | .600 | - | ESPN2 | Humphrey Coliseum · Starkville, MS |
| 14 | Tue Jan 19 | vs6Tennessee | W75-49 | 7-4 | .636 | - | ESPN | O'Connell Center · Gainesville, FL |
| 15 | Sat Jan 23 | atGeorgia | W92-84 | 8-4 | .667 | - | ESPN2 | Stegeman Coliseum · Athens, GA |
| 16 | Wed Jan 27 | vsVanderbilt | W78-71 | 9-4 | .692 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 17 | Sat Jan 30 | atWest Virginia | W85-80 | 10-4 | .714 | - | ESPN | WVU Coliseum · Morgantown, WV |
| 18 | Wed Feb 3 | vsSouth Carolina | L66-72 | 10-5 | .667 | #22 | SEC Network | O'Connell Center · Gainesville, FL |
| 21 | Tue Feb 16 | at24Arkansas | L64-75 | 10-6 | .625 | - | ESPN2 | Bud Walton Arena · Fayetteville, AR |
| 22 | Sat Feb 20 | vsGeorgia | W70-63 | 11-6 | .647 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 23 | Tue Feb 23 | atAuburn | W74-57 | 12-6 | .667 | - | ESPN | Neville Arena · Auburn, AL |
| 24 | Sat Feb 27 | atKentucky | W71-67 | 13-6 | .684 | - | CBS | Rupp Arena · Lexington, KY |
| 25 | Wed Mar 3 | vsMissouri | L70-72 | 13-7 | .650 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 26 | Sun Mar 7 | atTennessee | L54-65 | 13-8 | .619 | - | ESPNU | Thompson-Boling Arena · Knoxville, TN |
| 27 | Thu Mar 11 | vsVanderbilt | W69-63 | 14-8 | .636 | - | SEC Network | O'Connell Center · Gainesville, FL |
| 28 | Fri Mar 12 | atTennessee | L66-78 | 14-9 | .609 | - | ESPN | Thompson-Boling Arena · Knoxville, TN |
| 24 | Fri Mar 19 | vs10Virginia Tech | W75-70 (OT) | 15-9 | .625 | #7 | CBS | Hinkle Fieldhouse · Indianapolis, IN |
| 25 | Sun Mar 21 | vs15Oral Roberts | L78-81 | 15-10 | .600 | #7 | truTV | Indiana Farmers Coliseum · Indianapolis, IN |
