| 1 | Mon Nov 7 | at USC | W74-61 | 1-0 | 1.000 | - | | Galen Center · Los Angeles, CA |
| 2 | Wed Nov 9 | at San Diego | L73-79 | 1-1 | .500 | - | | Jenny Craig Pavilion · San Diego, CA |
| 3 | Sun Nov 13 | vs TBD | W105-61 | 2-1 | .667 | - | | Alico Arena · Fort Myers, FL |
| 4 | Wed Nov 16 | at #22Tennessee | L50-81 | 2-2 | .500 | - | | Thompson-Boling Arena · Knoxville, TN |
| 5 | Mon Nov 21 | at N Kentucky | W82-61 | 3-2 | .600 | - | | Truist Arena · Highland Heights, KY |
| 6 | Tue Nov 22 | at Drexel | W67-59 | 4-2 | .667 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 7 | Wed Nov 23 | at Kansas City | W73-59 | 5-2 | .714 | - | | Swinney Recreation Center · Kansas City, MO |
| 8 | Wed Nov 30 | at Georgia So | W70-53 | 6-2 | .750 | - | | W.S. Hanner Fieldhouse · Statesboro, GA |
| 9 | Sun Dec 4 | vs FIU | W74-65 | 7-2 | .778 | - | | Alico Arena · Fort Myers, FL |
| 10 | Wed Dec 7 | at FAU | L53-85 | 7-3 | .700 | - | | FAU Arena · Boca Raton, FL |
| 11 | Sat Dec 10 | vs Mercer | W67-62 | 8-3 | .727 | - | | Alico Arena · Fort Myers, FL |
| 12 | Fri Dec 16 | at St Bonaventure | W71-58 | 9-3 | .750 | - | | Reilly Center · Saint Bonaventure, NY |
| 13 | Wed Dec 21 | vs Canisius | W84-81 | 10-3 | .769 | - | | Alico Arena · Fort Myers, FL |
| 14 | Sat Dec 31 | vs Jacksonville | W72-65 | 11-3 | .786 | - | | Alico Arena · Fort Myers, FL |
| 15 | Mon Jan 2 | at C Arkansas | W84-79 (OT) | 12-3 | .800 | - | | Farris Center · Conway, AR |
| 16 | Thu Jan 5 | at Austin Peay | L59-61 | 12-4 | .750 | - | | Winfield Dunn Center · Clarksville, TN |
| 17 | Sat Jan 7 | vs North Florida | W82-57 | 13-4 | .765 | - | | Alico Arena · Fort Myers, FL |
| 18 | Thu Jan 12 | at E Kentucky | L76-97 | 13-5 | .722 | - | | McBrayer Arena · Richmond, KY |
| 19 | Sat Jan 14 | at Bellarmine | L41-61 | 13-6 | .684 | - | | Knights Hall · Louisville, KY |
| 20 | Thu Jan 19 | vs J'Ville St | W55-51 | 14-6 | .700 | - | | Alico Arena · Fort Myers, FL |
| 21 | Sat Jan 21 | vs Kennesaw St | L63-65 | 14-7 | .667 | - | | Alico Arena · Fort Myers, FL |
| 22 | Thu Jan 26 | at Queens | L82-84 | 14-8 | .636 | - | | Curry Arena · Charlotte, NC |
| 23 | Sat Jan 28 | at Liberty | L57-74 | 14-9 | .609 | - | | Liberty Arena · Lynchburg, VA |
| 24 | Thu Feb 2 | vsC Arkansas | L87-91 | 14-10 | .583 | - | | Alico Arena · Fort Myers, FL |
| 25 | Sat Feb 4 | vs North Alabama | L85-87 (OT) | 14-11 | .560 | - | | Alico Arena · Fort Myers, FL |
| 26 | Thu Feb 9 | atNorth Florida | W68-66 | 15-11 | .577 | - | | UNF Arena · Jacksonville, FL |
| 27 | Sat Feb 11 | atJacksonville | W62-51 | 16-11 | .593 | - | | Swisher Gymnasium · Jacksonville, FL |
| 28 | Wed Feb 15 | at Stetson | L72-75 | 16-12 | .571 | - | | Edmunds Center · Deland, FL |
| 29 | Sat Feb 18 | vsStetson | L84-88 | 16-13 | .552 | - | | Alico Arena · Fort Myers, FL |
| 30 | Wed Feb 22 | vs Lipscomb | L64-73 | 16-14 | .533 | - | | Alico Arena · Fort Myers, FL |
| 31 | Fri Feb 24 | vsAustin Peay | W89-71 | 17-14 | .548 | - | | Alico Arena · Fort Myers, FL |
| 32 | Mon Feb 27 | atQueens | L55-61 | 17-15 | .531 | - | | Curry Arena · Charlotte, NC |
